ENSMUSG00000010342


Mus musculus

Features
Gene ID: ENSMUSG00000010342
  
Biological name :Tex14
  
Synonyms : Inactive serine/threonine-protein kinase TEX14 / Q7M6U3 / Tex14
  
Possible biological names infered from orthology : Q8IWB6 / testis expressed 14, intercellular bridge forming factor
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: C
Gene start: 87405065
Gene end: 87555823
  
Corresponding Affymetrix probe sets: 10380025 (MoGene1.0st)   1419240_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000054444
Ensembl peptide - ENSMUSP00000098222
Ensembl peptide - ENSMUSP00000117564
Ensembl peptide - ENSMUSP00000118114
NCBI entrez gene - 83560     See in Manteia.
MGI - MGI:1933227
RefSeq - XM_017314857
RefSeq - NM_001199293
RefSeq - NM_031386
RefSeq - XM_011249327
RefSeq - XM_011249328
RefSeq - XM_011249329
RefSeq - XM_017314855
RefSeq - XM_017314856
RefSeq Peptide - NP_001186222
RefSeq Peptide - NP_113563
swissprot - B2KGK9
swissprot - Q5ND20
swissprot - Q5ND21
swissprot - Q7M6U3
Ensembl - ENSMUSG00000010342
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TEX14ENSGALG00000005037Gallus gallus
 TEX14ENSG00000121101Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR002110  Ankyrin repeat
 IPR011009  Protein kinase-like domain superfamily
 IPR020683  Ankyrin repeat-containing domain
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007094 mitotic spindle assembly checkpoint IMP
 biological_processGO:0007140 male meiotic nuclear division IMP
 biological_processGO:0008608 attachment of spindle microtubules to kinetochore IMP
 biological_processGO:0032091 negative regulation of protein binding IDA
 biological_processGO:0032466 negative regulation of cytokinesis IDA
 biological_processGO:0043063 intercellular bridge organization IDA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051306 mitotic sister chromatid separation IMP
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEP
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005623 cell IMP
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0045171 intercellular bridge IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Ednrbtm1(tTA)Tilg/Ednrbtm3(tetO)Tilg
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv

Allelic Composition: Tex14tm1Zuk/Tex14tm1Zuk
Genetic Background: either: (involves: 129S7/SvEvBrd * C57BL/6J) or (involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6J)

 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
Show

Allelic Composition: Ednrbtm1(tTA)Tilg/Ednrbtm3(tetO)Tilg
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Ednrbtm1(tTA)Tilg/Ednrbtm3(tetO)Tilg
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv

Allelic Composition: Tex14tm1Zuk/Tex14tm1Zuk
Genetic Background: either: (involves: 129S7/SvEvBrd * C57BL/6J) or (involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6J)

 MP:0001929 abnormal gametogenesis "defective formation or differentiation of germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:42324]
Show

Allelic Composition: Ednrbtm1(tTA)Tilg/Ednrbtm3(tetO)Tilg
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv

 MP:0002784 abnormal Sertoli cell morphology "malformation of the cells of the seminiferous tubules that create the blood-testes barrier and enable spermatogenesis" [J:65900, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ednrbtm1(tTA)Tilg/Ednrbtm3(tetO)Tilg
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ednrbtm1(tTA)Tilg/Ednrbtm3(tetO)Tilg
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv

 MP:0006379 abnormal spermatocyte morphology "anomaly in the number or structure of male germ cells that through meiosis give rise to spermatids " [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ednrbtm1(tTA)Tilg/Ednrbtm3(tetO)Tilg
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Ednrbtm1(tTA)Tilg/Ednrbtm3(tetO)Tilg
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv

Allelic Composition: Tex14tm1Zuk/Tex14tm1Zuk
Genetic Background: either: (involves: 129S7/SvEvBrd * C57BL/6J) or (involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6J)

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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