ENSMUSG00000010796


Mus musculus

Features
Gene ID: ENSMUSG00000010796
  
Biological name :Asz1
  
Synonyms : Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 / Asz1 / Q8VD46
  
Possible biological names infered from orthology : ankyrin repeat, SAM and basic leucine zipper domain containing 1 / Q8WWH4
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: A2
Gene start: 18050964
Gene end: 18109061
  
Corresponding Affymetrix probe sets: 10543259 (MoGene1.0st)   1422402_a_at (Mouse Genome 430 2.0 Array)   1424939_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000010940
Ensembl peptide - ENSMUSP00000122680
NCBI entrez gene - 74068     See in Manteia.
MGI - MGI:1921318
RefSeq - XM_006505178
RefSeq - NM_023729
RefSeq - XM_006505176
RefSeq Peptide - NP_076218
swissprot - Q8VD46
swissprot - D6RFV1
Ensembl - ENSMUSG00000010796
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 asz1ENSDARG00000004823Danio rerio
 ASZ1ENSGALG00000034574Gallus gallus
 ASZ1ENSG00000154438Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001660  Sterile alpha motif domain
 IPR002110  Ankyrin repeat
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR020683  Ankyrin repeat-containing domain
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007140 male meiotic nuclear division IMP
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007281 germ cell development NAS
 biological_processGO:0007283 spermatogenesis IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0034587 piRNA metabolic process IMP
 biological_processGO:0043046 DNA methylation involved in gamete generation IMP
 biological_processGO:0051321 meiotic cell cycle IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0071546 pi-body IDA
 molecular_functionGO:0004871 obsolete signal transducer activity NAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001155 arrest of spermatogenesis "block of the process by which spermatogonial stem cells divide and differentiate into spermatozoa" [J:62271]
Show

Allelic Composition: Trim71Gt(XD089)Byg/Trim71Gt(XD089)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Trim71Gt(XD089)Byg/Trim71Gt(XD089)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Trim71Gt(XD089)Byg/Trim71Gt(XD089)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0005169 abnormal male meiosis "malfunction in the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Trim71Gt(XD089)Byg/Trim71Gt(XD089)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0006379 abnormal spermatocyte morphology "anomaly in the number or structure of male germ cells that through meiosis give rise to spermatids " [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Trim71Gt(XD089)Byg/Trim71Gt(XD089)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0008866 chromosomal instability "abnormalities of DNA metabolism, DNA repair, cell-cycle governance, or control of apoptosis that increase the probability that whole chromosomes or pieces of chromosomes are gained or lost during cell division, resulting in an imbalance in the number of chromosomes per cell (aneuploidy) and an enhanced rate of loss of heterozygosity" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", PMID:12446840]
Show

Allelic Composition: Trim71Gt(XD089)Byg/Trim71Gt(XD089)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0008878 abnormal DNA methylation during gametogenesis "any anomaly of the covalent transfer of a methyl group to C-5 of cytosine during gamete generation, when DNA methylation patterns are established" [GO:0043046]
Show

Allelic Composition: Trim71Gt(XD089)Byg/Trim71Gt(XD089)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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