ENSMUSG00000011263


Mus musculus

Features
Gene ID: ENSMUSG00000011263
  
Biological name :Exoc3l2
  
Synonyms : Exoc3l2
  
Possible biological names infered from orthology : exocyst complex component 3 like 2 / Q2M3D2
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: A3
Gene start: 19463331
Gene end: 19496762
  
Corresponding Affymetrix probe sets: 10550706 (MoGene1.0st)   1428867_at (Mouse Genome 430 2.0 Array)   1438639_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000011407
Ensembl peptide - ENSMUSP00000123025
NCBI entrez gene - 74463     See in Manteia.
MGI - MGI:1921713
RefSeq - XM_006540475
swissprot - E9Q180
swissprot - D3YUP5
Ensembl - ENSMUSG00000011263
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 exoc3l2aENSDARG00000008414Danio rerio
 exoc3l2bENSDARG00000030782Danio rerio
 Q2M3D2ENSG00000283632Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BI71 / Exoc3l / Mus musculus exocyst complex component 3-like (Exoc3l), transcript variant 2, mRNA. / Q86VI1* / EXOC3L1* / exocyst complex component 3 like 1*ENSMUSG0000004325123
Exoc3l4 / exocyst complex component 3 like 4 / Q17RC7*ENSMUSG0000002128022
Q61333 / Tnfaip2 / tumor necrosis factor, alpha-induced protein 2 / Q03169* / TNF alpha induced protein 2*ENSMUSG0000002128120
Exoc3 / Q6KAR6 / Exocyst complex component 3 / O60645*ENSMUSG0000003415220


Protein motifs (from Interpro)
Interpro ID Name
 IPR010326  Exocyst complex component EXOC3/Sec6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006887 exocytosis IBA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0051601 exocyst localization IBA
 cellular_componentGO:0000145 exocyst IBA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0000149 SNARE binding IBA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000438 abnormal skull morphology "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Dnmt3atm1b(KOMP)Wtsi/Dnmt3atm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Dnmt3atm1b(KOMP)Wtsi/J

 MP:0000443 abnormal snout morphology "anomalous structure or development of the anterior facial part of the muzzle" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Dnmt3atm1b(KOMP)Wtsi/Dnmt3atm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Dnmt3atm1b(KOMP)Wtsi/J

 MP:0000602 enlarged sinusoidal spaces "larger than normal sized cavities in the liver " [J:23170]
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Allelic Composition: Ewsr1tm1b(EUCOMM)Wtsi/Ewsr1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Ewsr1tm1b(EUCOMM)Wtsi/Tcp

 MP:0002100 abnormal tooth morphology "atypical size, shape or hard tissue structure of the teeth " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Dnmt3atm1b(KOMP)Wtsi/Dnmt3atm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Dnmt3atm1b(KOMP)Wtsi/J

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ewsr1tm1b(EUCOMM)Wtsi/Ewsr1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Ewsr1tm1b(EUCOMM)Wtsi/Tcp

 MP:0005554 decreased circulating creatinine level "less than the normal blood concentration of this product of creatine catabolism; abnormal levels indicative of renal dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Ewsr1tm1b(EUCOMM)Wtsi/Ewsr1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Ewsr1tm1b(EUCOMM)Wtsi/Tcp

 MP:0008207 decreased B-2 cell number "reduced number of conventional B cells subject to antigenic stimulation and dependent on T cell help and with a distinct surface marker expression pattern from B-1 B cells" [CL:0000822, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:11861604]
Show

Allelic Composition: Ewsr1tm1b(EUCOMM)Wtsi/Ewsr1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Ewsr1tm1b(EUCOMM)Wtsi/Tcp

 MP:0008810 increased circulating iron level "elevation in the concentration of iron in the blood" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Ewsr1tm1b(EUCOMM)Wtsi/Ewsr1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Ewsr1tm1b(EUCOMM)Wtsi/Tcp

 MP:0010912 herniated liver "protrusion of any portion of the liver from its normal anatomical position" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Ewsr1tm1b(EUCOMM)Wtsi/Ewsr1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Ewsr1tm1b(EUCOMM)Wtsi/Tcp

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Ewsr1tm1b(EUCOMM)Wtsi/Ewsr1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Ewsr1tm1b(EUCOMM)Wtsi/Tcp

 MP:0013878 abnormal ductus venosus valve topology "abnormal position of the valve present on the right side of the ductus venosus at the site of the junction with the inferior vena cava" [PMID:5438957]
Show

Allelic Composition: Ewsr1tm1b(EUCOMM)Wtsi/Ewsr1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Ewsr1tm1b(EUCOMM)Wtsi/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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