ENSMUSG00000012640


Mus musculus

Features
Gene ID: ENSMUSG00000012640
  
Biological name :Zfp715
  
Synonyms : Zfp715 / zinc finger protein 715
  
Possible biological names infered from orthology : P51508 / Q9Y473 / zinc finger protein 175 / zinc finger protein 81 / ZNF175 / ZNF81
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: B3
Gene start: 43296197
Gene end: 43313294
  
Corresponding Affymetrix probe sets: 10562670 (MoGene1.0st)   1432439_at (Mouse Genome 430 2.0 Array)   1434461_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000122812
Ensembl peptide - ENSMUSP00000114600
Ensembl peptide - ENSMUSP00000138240
Ensembl peptide - ENSMUSP00000012796
Ensembl peptide - ENSMUSP00000040282
Ensembl peptide - ENSMUSP00000103620
NCBI entrez gene - 69930     See in Manteia.
MGI - MGI:1917180
RefSeq - XM_011250901
RefSeq - NM_001357811
RefSeq - NM_001357812
RefSeq - NM_027264
RefSeq - XM_006541180
RefSeq - XM_006541182
RefSeq - XM_006541183
RefSeq - XM_006541184
RefSeq - XM_006541185
RefSeq Peptide - NP_001344740
RefSeq Peptide - NP_001344741
RefSeq Peptide - NP_081540
swissprot - S4R1I9
swissprot - G3X9T1
swissprot - D3YV82
swissprot - D3Z3C8
swissprot - Q9D082
Ensembl - ENSMUSG00000012640
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q9Y473ENSG00000105497Homo sapiens
 ZNF81ENSG00000197779Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Zfp719 / zinc finger protein 719 / ZNF81* / Q9Y473* / ZNF175* / P51508* / zinc finger protein 81* / zinc finger protein 175*ENSMUSG0000003046941
Zfp819 / zinc finger protein 819 / ZNF81* / Q9Y473* / ZNF175* / P51508* / zinc finger protein 81* / zinc finger protein 175*ENSMUSG0000005510233


Protein motifs (from Interpro)
Interpro ID Name
 IPR001909  Krueppel-associated box
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036051  KRAB domain superfamily
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISO
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0045111 intermediate filament cytoskeleton ISO
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding ISO
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Generic Transcription Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003062 abnormal coping response "altered ability to respond productively to a stressful situation or stimulus, or failure to seek pleasurable stimuli" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
Genetic Background: C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics

 MP:0005178 increased total circulating cholesterol level "greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
Genetic Background: C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics

 MP:0005179 decreased total circulating cholesterol level "less than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
Genetic Background: C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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