ENSMUSG00000013662


Mus musculus

Features
Gene ID: ENSMUSG00000013662
  
Biological name :Atad1
  
Synonyms : Atad1 / ATPase family AAA domain-containing protein 1 / Q9D5T0
  
Possible biological names infered from orthology : ATPase family, AAA domain containing 1 / Q8NBU5
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: C1
Gene start: 32672563
Gene end: 32712298
  
Corresponding Affymetrix probe sets: 10467091 (MoGene1.0st)   1417555_at (Mouse Genome 430 2.0 Array)   1446838_at (Mouse Genome 430 2.0 Array)   1448763_at (Mouse Genome 430 2.0 Array)   1456382_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000069962
NCBI entrez gene - 67979     See in Manteia.
MGI - MGI:1915229
RefSeq - NM_026487
RefSeq - XM_006527313
RefSeq Peptide - NP_080763
swissprot - Q9D5T0
Ensembl - ENSMUSG00000013662
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atad1bENSDARG00000056609Danio rerio
 ATAD1ENSGALG00000003652Gallus gallus
 ATAD1ENSG00000138138Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR003959  ATPase, AAA-type, core
 IPR003960  ATPase, AAA-type, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002092 positive regulation of receptor internalization IMP
 biological_processGO:0007612 learning IMP
 biological_processGO:0007613 memory IMP
 biological_processGO:0051967 negative regulation of synaptic transmission, glutamatergic IMP
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Atad1tm1.1Vdaw/Atad1tm1.1Vdaw
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0001899 absent long term depression "lack of the normal, persistent activity-dependent decrease in synaptic efficacy between neurons, often following slow, weak stimulation of CA1 neurons" [Principles of Neural Science:ISBN 0-8385-8034-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Atad1tm1.1Vdaw/Atad1tm1.1Vdaw
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0002064 seizures "sudden and often acute manifestation of epileptic attack, sometimes convulsive" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ccm2tm2.1Sbn/Ccm2tm2.1Sbn,Tg(Mx1-cre)1Cgn/0
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Atad1tm1.1Vdaw/Atad1tm1.1Vdaw
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Atad1tm1.1Vdaw/Atad1tm1.1Vdaw
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0003008 enhanced long term potentiation "greater than the normal persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells " [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3, J:81922]
Show

Allelic Composition: Atad1tm1.1Vdaw/Atad1tm1.1Vdaw
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0004753 abnormal miniature excitatory postsynaptic currents "defect in the size or duration of spontaneous currents detected in postsynaptic cells that occur in the absence of an excitatory impulse" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Atad1tm1.1Vdaw/Atad1tm1.1Vdaw
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0008428 abnormal spatial working memory "anomaly in the ability to spontaneously process spatial location information in order to naviagate or perform other behavior using such locational cues, without previous encounters or training at that location" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ccm2tm2.1Sbn/Ccm2tm2.1Sbn,Tg(Mx1-cre)1Cgn/0
Genetic Background: involves: C57BL/6 * CBA

 MP:0008431 abnormal short-term spatial reference memory "anomaly in the short-term memory for spatial location information that is established during the first few minutes after training or an encouter at that location" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ccm2tm2.1Sbn/Ccm2tm2.1Sbn,Tg(Mx1-cre)1Cgn/0
Genetic Background: involves: C57BL/6 * CBA

 MP:0011002 enhanced AMPA-mediated synaptic currents "increase in the measured amplitude, current density or duration of response to stimulation of AMPA receptors" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Atad1tm1.1Vdaw/Atad1tm1.1Vdaw
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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