ENSMUSG00000013701


Mus musculus

Features
Gene ID: ENSMUSG00000013701
  
Biological name :Timm23
  
Synonyms : Timm23 / translocase of inner mitochondrial membrane 23
  
Possible biological names infered from orthology : O14925 / Q5SRD1 / TIMM23B / translocase of inner mitochondrial membrane 23 homolog B
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: B
Gene start: 32180162
Gene end: 32201898
  
Corresponding Affymetrix probe sets: 10360225 (MoGene1.0st)   10363368 (MoGene1.0st)   10416069 (MoGene1.0st)   10418804 (MoGene1.0st)   1416485_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000126977
Ensembl peptide - ENSMUSP00000154804
Ensembl peptide - ENSMUSP00000129688
Ensembl peptide - ENSMUSP00000013845
NCBI entrez gene - 53600     See in Manteia.
MGI - MGI:1858317
RefSeq - NM_016897
RefSeq Peptide - NP_058593
swissprot - E9Q3T4
swissprot - E9PVF9
swissprot - Q9CXU4
Ensembl - ENSMUSG00000013701
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 timm23aENSDARG00000071396Danio rerio
 timm23bENSDARG00000100375Danio rerio
 ENSGALG00000002089Gallus gallus
 O14925ENSG00000265354Homo sapiens
 Q5SRD1ENSG00000204152Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm10273 / O14925* / Q5SRD1* / TIMM23* / TIMM23B* / translocase of inner mitochondrial membrane 23* / translocase of inner mitochondrial membrane 23 homolog B*ENSMUSG00000069622100


Protein motifs (from Interpro)
Interpro ID Name
 IPR005681  Mitochondrial inner membrane translocase complex, subunit Tim23


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0071806 protein transmembrane transport IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0005744 mitochondrial inner membrane presequence translocase complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000160 kyphosis "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: Lepob/Lepob,Nr1i3tm1Dgen/Nr1i3tm1Dgen
Genetic Background: B6.Cg-Nr1i3tm1Dgen Lepob

 MP:0000414 alopecia "absence of hair or loss of hair; not usually in reference to primary genetic hairlessness but may be due to dietary, stress, secondary to immune condition" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:30772, J:33796]
Show

Allelic Composition: Lepob/Lepob,Nr1i3tm1Dgen/Nr1i3tm1Dgen
Genetic Background: B6.Cg-Nr1i3tm1Dgen Lepob

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Lepob/Lepob,Nr1i3tm1Dgen/Nr1i3tm1Dgen
Genetic Background: B6.Cg-Nr1i3tm1Dgen Lepob

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Lepob/Lepob,Nr1i3tm1Dgen/Nr1i3tm1Dgen
Genetic Background: B6.Cg-Nr1i3tm1Dgen Lepob

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Lepob/Lepob,Nr1i3tm1Dgen/Nr1i3tm1Dgen
Genetic Background: B6.Cg-Nr1i3tm1Dgen Lepob

 MP:0003786 premature aging "earlier than normal occurence of the normal signs of aging" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:97764]
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Allelic Composition: Lepob/Lepob,Nr1i3tm1Dgen/Nr1i3tm1Dgen
Genetic Background: B6.Cg-Nr1i3tm1Dgen Lepob

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Lepob/Lepob,Nr1i3tm1Dgen/Nr1i3tm1Dgen
Genetic Background: B6.Cg-Nr1i3tm1Dgen Lepob

 MP:0011094 complete embryonic lethality before implantation "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
Show

Allelic Composition: Lepob/Lepob,Nr1i3tm1Dgen/Nr1i3tm1Dgen
Genetic Background: B6.Cg-Nr1i3tm1Dgen Lepob

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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