ENSMUSG00000013973


Mus musculus

Features
Gene ID: ENSMUSG00000013973
  
Biological name :Dedd
  
Synonyms : Death effector domain-containing protein / Dedd / Q9Z1L3
  
Possible biological names infered from orthology : death effector domain containing / O75618
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: H3
Gene start: 171329145
Gene end: 171342331
  
Corresponding Affymetrix probe sets: 10351574 (MoGene1.0st)   1432000_a_at (Mouse Genome 430 2.0 Array)   1434994_at (Mouse Genome 430 2.0 Array)   1434995_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000106931
Ensembl peptide - ENSMUSP00000119948
Ensembl peptide - ENSMUSP00000122628
Ensembl peptide - ENSMUSP00000120993
Ensembl peptide - ENSMUSP00000120861
Ensembl peptide - ENSMUSP00000120278
Ensembl peptide - ENSMUSP00000068419
Ensembl peptide - ENSMUSP00000095075
Ensembl peptide - ENSMUSP00000106930
NCBI entrez gene - 21945     See in Manteia.
MGI - MGI:1333874
RefSeq - XM_011238782
RefSeq - XM_006496741
RefSeq - XM_006496740
RefSeq - XM_006496738
RefSeq - XM_006496739
RefSeq - NM_001128609
RefSeq - NM_011615
RefSeq Peptide - NP_001344481
RefSeq Peptide - NP_001122081
RefSeq Peptide - NP_001344479
RefSeq Peptide - NP_001344480
RefSeq Peptide - NP_001344482
RefSeq Peptide - NP_035745
swissprot - Q3U001
swissprot - Q9Z1L3
swissprot - D3Z4Q1
swissprot - A0A1C7ZMZ8
swissprot - D3YZI2
swissprot - D3Z0F7
swissprot - D3Z0I1
Ensembl - ENSMUSG00000013973
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 deddENSDARG00000029783Danio rerio
 DEDDENSGALG00000043129Gallus gallus
 DEDDENSG00000158796Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dedd2 / Q8QZV0 / DNA-binding death effector domain-containing protein 2 / Q8WXF8* / death effector domain containing 2*ENSMUSG0000005449943


Protein motifs (from Interpro)
Interpro ID Name
 IPR001875  Death effector domain
 IPR011029  Death-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0008625 extrinsic apoptotic signaling pathway via death domain receptors IDA
 biological_processGO:0042177 negative regulation of protein catabolic process IMP
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0046697 decidualization IMP
 biological_processGO:1901837 negative regulation of transcription of nucleolar large rRNA by RNA polymerase I IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Cebpatm6Nerl/Cebpatm6Nerl
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002175 low brain weight "lower than average weight of the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cebpatm6Nerl/Cebpatm6Nerl
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002834 decreased heart weight "less than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Cebpatm6Nerl/Cebpatm6Nerl
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003402 decreased liver weight "reduced average weight of the bile-secreting exocrine gland" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cebpatm6Nerl/Cebpatm6Nerl
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003918 decreased kidney weight "reduced heft of the organs responsible for urine secretion" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Cebpatm6Nerl/Cebpatm6Nerl
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cebpatm6Nerl/Cebpatm6Nerl
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004953 decreased spleen weight "reduction in the average weight of the organ that functions to filter blood and to store red corpuscles and platelets" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cebpatm6Nerl/Cebpatm6Nerl
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005631 decreased lung weight "less than the normal state of the physical heaviness of the lung" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Cebpatm6Nerl/Cebpatm6Nerl
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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