ENSMUSG00000013997


Mus musculus

Features
Gene ID: ENSMUSG00000013997
  
Biological name :Nit1
  
Synonyms : Deaminated glutathione amidase / Nit1 / Q8VDK1
  
Possible biological names infered from orthology : nitrilase 1 / Q86X76
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: H3
Gene start: 171338008
Gene end: 171345646
  
Corresponding Affymetrix probe sets: 10360130 (MoGene1.0st)   1417468_at (Mouse Genome 430 2.0 Array)   1417469_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000106926
Ensembl peptide - ENSMUSP00000119171
Ensembl peptide - ENSMUSP00000116835
Ensembl peptide - ENSMUSP00000106927
Ensembl peptide - ENSMUSP00000106920
NCBI entrez gene - 27045     See in Manteia.
MGI - MGI:1350916
RefSeq - XM_006496866
RefSeq - NM_001242580
RefSeq - NM_012049
RefSeq Peptide - NP_001229509
RefSeq Peptide - NP_036179
swissprot - Q8VDK1
swissprot - D3Z3I3
swissprot - D3YY53
swissprot - D3Z2Y2
Ensembl - ENSMUSG00000013997
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nit1ENSDARG00000070116Danio rerio
 NIT1ENSGALG00000007585Gallus gallus
 NIT1ENSG00000158793Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001110  Uncharacterised protein family UPF0012, conserved site
 IPR003010  Carbon-nitrogen hydrolase
 IPR036526  Carbon-nitrogen hydrolase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006807 nitrogen compound metabolic process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IDA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000358 abnormal cell content/ morphology "structural anomalies of the minute protoplasmic masses that make up organized tissues and which are the fundamental structural and functional units of living organisms" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Nit1tm1Hbn/Nit1tm1.1Hbn
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0000662 abnormal branching of the mammary ductal tree "anomaly in the development of the channels that secrete milk and direct milk to the nipple" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Nit1tm1Hbn/Nit1tm1.1Hbn
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Polhtm2Fmh/Polhtm2Fmh,Polid/Poli+
Genetic Background: B6.129-Polhtm2Fmh Polid

 MP:0003207 decreased sensitivity to gamma-irradiation "decreased incidence of cell death following high levels of gamma-irradiation" [J:92917, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Nit1tm1Hbn/Nit1tm1.1Hbn
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0004499 increased incidence of chemically-induced tumors "higher than normal frequency of tumor incidence induced by one or more chemical carcinogens or mutagens" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Polhtm2Fmh/Polhtm2Fmh,Polid/Poli+
Genetic Background: B6.129-Polhtm2Fmh Polid

Allelic Composition: Nit1tm1Hbn/Nit1tm1.1Hbn
Genetic Background: involves: 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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