ENSMUSG00000014601


Mus musculus

Features
Gene ID: ENSMUSG00000014601
  
Biological name :Strip1
  
Synonyms : Q8C079 / Striatin-interacting protein 1 / Strip1
  
Possible biological names infered from orthology : Q5VSL9
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F2.3
Gene start: 107612532
Gene end: 107631694
  
Corresponding Affymetrix probe sets: 10501121 (MoGene1.0st)   1454644_at (Mouse Genome 430 2.0 Array)   1457513_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000068587
NCBI entrez gene - 229707     See in Manteia.
MGI - MGI:2443884
RefSeq - NM_153563
RefSeq Peptide - NP_705791
swissprot - Q8C079
Ensembl - ENSMUSG00000014601
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 strip1ENSDARG00000074084Danio rerio
 STRIP1ENSGALG00000037995Gallus gallus
 Q5VSL9ENSG00000143093Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8C9H6 / Strip2 / Striatin-interacting proteins 2 / Q9ULQ0* / striatin interacting protein 2*ENSMUSG0000003962970


Protein motifs (from Interpro)
Interpro ID Name
 IPR012486  Far11/STRP, N-terminal
 IPR021819  Far11/STRP, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0022604 regulation of cell morphogenesis IEA
 biological_processGO:0030866 cortical actin cytoskeleton organization IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0017048 Rho GTPase binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001680 abnormal mesoderm development "failure or abnormality in the formation of the mesoderm during gastrulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Strip1cin/Strip1tm1a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N * FVB/N

Allelic Composition: Edil3Tg(Sox2-cre)1Amc/Edil3+,Strip1tm1b(KOMP)Wtsi/Strip1tm1c(KOMP)Wtsi
Genetic Background: involves: C57BL/6N * CBA * FVB/NJ * SJL

 MP:0002231 abnormal primitive streak morphology "anomaly in the midline ridge of the embryonic epiblast that later develops into mesoderm and endoderm" [The Atlas of Mouse Development:ISBN 0-12-402035-6, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Gt(ROSA)26Sorem1(CAG-TMEM14B,-EGFP)Xqw/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: C57BL/6 * SJL

Allelic Composition: Strip1tm1b(KOMP)Wtsi/Strip1tm1b(KOMP)Wtsi
Genetic Background: involves: C57BL/6 * C57BL/6N * FVB/NJ

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gt(ROSA)26Sorem1(CAG-TMEM14B,-EGFP)Xqw/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: C57BL/6 * SJL

 MP:0004187 cardia bifida "failure of the bilateral myocardial cells to coalesce into a single central heart tube resulting in the presence of two independent hearts" [smb:Susan M Bello, Mouse Genome Informatics Curator ""]
Show

Allelic Composition: Edil3Tg(Sox2-cre)1Amc/Edil3+,Strip1tm1b(KOMP)Wtsi/Strip1tm1c(KOMP)Wtsi
Genetic Background: involves: C57BL/6N * CBA * FVB/NJ * SJL

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: Gt(ROSA)26Sorem1(CAG-TMEM14B,-EGFP)Xqw/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: C57BL/6 * SJL

 MP:0011257 abnormal head fold morphology "any structural anomaly of the crescent-shaped, ventrally located fold of the embryonic disc at the future cephalic end of the developing embryo; it constitutes the first body fold, and initiates brain, foregut and heart development" [ISBN:0-683-40008-8, PMID:10791309]
Show

Allelic Composition: Edil3Tg(Sox2-cre)1Amc/Edil3+,Strip1tm1b(KOMP)Wtsi/Strip1tm1c(KOMP)Wtsi
Genetic Background: involves: C57BL/6N * CBA * FVB/NJ * SJL

 MP:0011708 decreased fibroblast cell migration "reduced frequency of or less rapid cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium" [MGI:csmith]
Show

Allelic Composition: Strip1tm1b(KOMP)Wtsi/Strip1tm1b(KOMP)Wtsi
Genetic Background: involves: C57BL/6 * C57BL/6N * FVB/NJ

 MP:0012135 embryonic-extraembryonic boundary constriction "an invagination or pinching in the visceral endoderm that is centered at the boundary between embryonic and extra-embryonic regions of the developing embryo, often resulting in physical separation of embryonic and extraembryonic ectoderm" [MGI:csmith]
Show

Allelic Composition: Gt(ROSA)26Sorem1(CAG-TMEM14B,-EGFP)Xqw/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: C57BL/6 * SJL

Allelic Composition: Strip1cin/Strip1tm1a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0012173 short rostral-caudal axis "length reduction or truncation of the axis that runs from the head to the tail of the body" [MGI:anna]
Show

Allelic Composition: Gt(ROSA)26Sorem1(CAG-TMEM14B,-EGFP)Xqw/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: C57BL/6 * SJL

Allelic Composition: Strip1tm1b(KOMP)Wtsi/Strip1tm1b(KOMP)Wtsi
Genetic Background: involves: C57BL/6 * C57BL/6N * FVB/NJ

Allelic Composition: Edil3Tg(Sox2-cre)1Amc/Edil3+,Strip1tm1b(KOMP)Wtsi/Strip1tm1c(KOMP)Wtsi
Genetic Background: involves: C57BL/6N * CBA * FVB/NJ * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr