ENSMUSG00000015476


Mus musculus

Features
Gene ID: ENSMUSG00000015476
  
Biological name :Prrt1
  
Synonyms : O35449 / proline-rich transmembrane protein 1 / Prrt1
  
Possible biological names infered from orthology : Q99946
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: B1
Gene start: 34629533
Gene end: 34633126
  
Corresponding Affymetrix probe sets: 10444431 (MoGene1.0st)   1423562_at (Mouse Genome 430 2.0 Array)   1423563_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000015620
NCBI entrez gene - 260297     See in Manteia.
MGI - MGI:1932118
RefSeq - XM_011246470
RefSeq - NM_030890
RefSeq Peptide - NP_112152
swissprot - O35449
swissprot - A2CG20
Ensembl - ENSMUSG00000015476
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prrt1ENSDARG00000062208Danio rerio
 PRRT1ENSG00000204314Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm13420 / proline rich transmembrane protein 1B / PRRT1B*ENSMUSG0000007949722


Protein motifs (from Interpro)
Interpro ID Name
 IPR007593  CD225/Dispanin family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0009607 response to biotic stimulus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IBA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001415 increased exploration in new environment "greater amount of time spent investigating new location" [J:28825]
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Allelic Composition: Adora2btm1Msit/Adora2btm1Msit,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: C57BL/6 * DBA/2

 MP:0001458 abnormal object recognition memory "defects in the ability to recognize objects that the animal has previously encountered; recognition is measured by relative amount of time exploring objects, which should decrease upon subsequent or multiple presentations of the same object when presented with novel objects at the same time" [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Adora2btm1Msit/Adora2btm1Msit,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: C57BL/6 * DBA/2

 MP:0001473 reduced long term potentiation "less than the normal persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells " [Principles of Neural Science:ISBN 0-8385-8034-3]
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Allelic Composition: Adora2btm1Msit/Adora2btm1Msit,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: C57BL/6 * DBA/2

 MP:0004753 abnormal miniature excitatory postsynaptic currents "defect in the size or duration of spontaneous currents detected in postsynaptic cells that occur in the absence of an excitatory impulse" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Adora2btm1Msit/Adora2btm1Msit,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: C57BL/6 * DBA/2

 MP:0012307 impaired spatial learning "impaired ability to ascertain or acquire spatial location information in order to improve navigation or other behavior using such location cues" [MGI:csmith]
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Allelic Composition: Adora2btm1Msit/Adora2btm1Msit,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: C57BL/6 * DBA/2

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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