ENSMUSG00000015597


Mus musculus

Features
Gene ID: ENSMUSG00000015597
  
Biological name :Zfp318
  
Synonyms : Zfp318 / zinc finger protein 318
  
Possible biological names infered from orthology : Q5VUA4 / ZNF318
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: C
Gene start: 46383731
Gene end: 46420920
  
Corresponding Affymetrix probe sets: 10445531 (MoGene1.0st)   1421478_a_at (Mouse Genome 430 2.0 Array)   1421479_at (Mouse Genome 430 2.0 Array)   1425346_at (Mouse Genome 430 2.0 Array)   1425347_a_at (Mouse Genome 430 2.0 Array)   1430558_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000116544
Ensembl peptide - ENSMUSP00000109109
Ensembl peptide - ENSMUSP00000116132
NCBI entrez gene - 57908     See in Manteia.
MGI - MGI:1889348
RefSeq - XM_011246554
RefSeq - NM_021346
RefSeq - NM_207671
RefSeq Peptide - NP_997554
RefSeq Peptide - NP_067321
swissprot - B0V2M3
swissprot - F6R9J2
swissprot - B8JJA0
Ensembl - ENSMUSG00000015597
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 znf318ENSDARG00000090054Danio rerio
 ZNF318ENSGALG00000034040Gallus gallus
 Q5VUA4ENSG00000171467Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003604  Matrin/U1-C-like, C2H2-type zinc finger


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
Show

Allelic Composition: Btkm2Anu/Btkm2Anu
Genetic Background: C57BL/6NCrlAnu-Btkm2Anu

 MP:0002458 abnormal B cell number "deviation from the normal number of B lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Btkm2Anu/Btkm2Anu
Genetic Background: C57BL/6NCrlAnu-Btkm2Anu

 MP:0002491 decreased IgD "less than normal immunoglobulin class D level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Btkm2Anu/Btkm2Anu
Genetic Background: C57BL/6NCrlAnu-Btkm2Anu

Allelic Composition: Zfp318m1Anu/Zfp318+
Genetic Background: C57BL/6JAnu-Zfp318m1Anu

Allelic Composition: Zfp318tm1Hhag/Zfp318tm1Hhag
Genetic Background: involves: 129 * C57BL/6

Allelic Composition: Zfp318tm1.1Jhws/Zfp318tm1.1Jhws,Commd10Tg(Vav1-icre)A2Kio/Commd10+
Genetic Background: B6.Cg-Zfp318tm1.1Jhws TgVav1-creA2Kio

Allelic Composition: Zfp318M1Btlr/Zfp318M1Btlr
Genetic Background: C57BL/6J-Zfp318M1Btlr

Allelic Composition: Zfp318M1Btlr/Zfp318+
Genetic Background: C57BL/6J-Zfp318M1Btlr

 MP:0002494 increased IgM "greater than normal immunoglobulin class M level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Btkm2Anu/Btkm2Anu
Genetic Background: C57BL/6NCrlAnu-Btkm2Anu

Allelic Composition: Zfp318m1Anu/Zfp318+
Genetic Background: C57BL/6JAnu-Zfp318m1Anu

Allelic Composition: Zfp318tm1Hhag/Zfp318tm1Hhag
Genetic Background: involves: 129 * C57BL/6

Allelic Composition: Zfp318tm1.1Jhws/Zfp318tm1.1Jhws,Commd10Tg(Vav1-icre)A2Kio/Commd10+
Genetic Background: B6.Cg-Zfp318tm1.1Jhws TgVav1-creA2Kio

 MP:0008191 abnormal follicular B cell physiology "abnormal function of a resting mature B cell with distinct phenotypic characteristics (CD23-positive, CD21-positive) found typically in the B cell follicle region of the spleen" [CL:0000843, ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Btkm2Anu/Btkm2Anu
Genetic Background: C57BL/6NCrlAnu-Btkm2Anu

 MP:0008193 abnormal marginal zone B cell physiology "abnormal function of a CD23-negative, CD21-positive B cell of the marginal zone of the spleen expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL" [CL:0000845, ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Btkm2Anu/Btkm2Anu
Genetic Background: C57BL/6NCrlAnu-Btkm2Anu

 MP:0008210 increased mature B cell number "greater number of the mature form of B cells, a type of lymphocyte whose defining characteristic is the expression of an immunoglobulin complex" [CL:0000785, ISBN:0781735149]
Show

Allelic Composition: Btkm2Anu/Btkm2Anu
Genetic Background: C57BL/6NCrlAnu-Btkm2Anu

 MP:0009926 decreased transitional stage T2 B cell number "reduced number of a type of transitional stage B cell that has the phenotype surface IgM-positive, surface IgD-postive, CD21-positive, CD23-positive, CD62L-negative, and is located in the splenic B follicles" [PMID:12810111]
Show

Allelic Composition: Zfp318tm1.1Jhws/Zfp318tm1.1Jhws,Commd10Tg(Vav1-icre)A2Kio/Commd10+
Genetic Background: B6.Cg-Zfp318tm1.1Jhws TgVav1-creA2Kio

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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