ENSMUSG00000015745


Mus musculus

Features
Gene ID: ENSMUSG00000015745
  
Biological name :Plekho1
  
Synonyms : Pleckstrin homology domain-containing family O member 1 / Plekho1 / Q9JIY0
  
Possible biological names infered from orthology : pleckstrin homology domain containing O1 / Q53GL0
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F2.1
Gene start: 95988429
Gene end: 95996001
  
Corresponding Affymetrix probe sets: 10500295 (MoGene1.0st)   1417128_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000015889
Ensembl peptide - ENSMUSP00000114505
Ensembl peptide - ENSMUSP00000115035
Ensembl peptide - ENSMUSP00000118665
NCBI entrez gene - 67220     See in Manteia.
MGI - MGI:1914470
RefSeq - XM_006501930
RefSeq - NM_023320
RefSeq Peptide - NP_075809
swissprot - F6VV25
swissprot - D3YVD1
swissprot - Q9JIY0
swissprot - F6XQM2
Ensembl - ENSMUSG00000015745
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plekho1aENSDARG00000061191Danio rerio
 plekho1bENSDARG00000077499Danio rerio
 PLEKHO1ENSGALG00000037540Gallus gallus
 Q53GL0ENSG00000023902Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8K124 / Plekho2 / Pleckstrin homology domain-containing family O member 2 / AC069368.1*ENSMUSG0000005072128


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR028452  Pleckstrin homology domain-containing family O member 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007520 myoblast fusion IMP
 biological_processGO:0008360 regulation of cell shape IMP
 biological_processGO:0051451 myoblast migration IMP
 biological_processGO:0072673 lamellipodium morphogenesis IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0032587 ruffle membrane IDA
 cellular_componentGO:0036195 muscle cell projection membrane IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002113 abnormal skeleton development "anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Grin1tm1Rsp/Grin1tm1Rsp,Tg(Slc6a3-icre)9075Gsc/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

 MP:0005006 abnormal osteoblast function "anomalous function of this bone-forming cell, which normally forms an osseous matrix in which it becomes enclosed as an osteocyte " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Grin1tm1Rsp/Grin1tm1Rsp,Tg(Slc6a3-icre)9075Gsc/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

 MP:0005605 increased bone mass "an increase in the total amount of bone tissue contained in the skeleton" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Grin1tm1Rsp/Grin1tm1Rsp,Tg(Slc6a3-icre)9075Gsc/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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