ENSMUSG00000017561


Mus musculus

Features
Gene ID: ENSMUSG00000017561
  
Biological name :Crlf3
  
Synonyms : Crlf3 / Cytokine receptor-like factor 3 / Q9Z2L7
  
Possible biological names infered from orthology : Q8IUI8
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: B5
Gene start: 80046493
Gene end: 80080991
  
Corresponding Affymetrix probe sets: 10388996 (MoGene1.0st)   1438235_at (Mouse Genome 430 2.0 Array)   1460338_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000137371
Ensembl peptide - ENSMUSP00000060028
Ensembl peptide - ENSMUSP00000136473
Ensembl peptide - ENSMUSP00000099523
Ensembl peptide - ENSMUSP00000137124
NCBI entrez gene - 54394     See in Manteia.
MGI - MGI:1860086
RefSeq - NM_001277106
RefSeq - NM_018776
RefSeq Peptide - NP_001264035
RefSeq Peptide - NP_061246
swissprot - Q9Z2L7
swissprot - J3QMV5
swissprot - J3QP70
swissprot - J3QPM4
Ensembl - ENSMUSG00000017561
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 crlf3ENSDARG00000070261Danio rerio
 CRLF3ENSGALG00000003284Gallus gallus
 CRLF3ENSG00000176390Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle IEA
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046427 positive regulation of JAK-STAT cascade IEA
 biological_processGO:0071158 positive regulation of cell cycle arrest IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Chd7tm2a(EUCOMM)Wtsi/Chd7+
Genetic Background: 129S5;B6N-Chd7tm2a(EUCOMM)Wtsi/Wtsi

 MP:0002591 decreased mean corpuscular volume "less than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Cpsf3tm1b(EUCOMM)Wtsi/Cpsf3tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cpsf3tm1b(EUCOMM)Wtsi/Wtsi

 MP:0003179 decreased platelet count "fewer than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, hdene:Howard Dene , Mouse Genome Informatics Curator, J:93052]
Show

Allelic Composition: Cpsf3tm1b(EUCOMM)Wtsi/Cpsf3tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cpsf3tm1b(EUCOMM)Wtsi/Wtsi

Allelic Composition: Crlf3tm1a(KOMP)Wtsi/Crlf3tm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Crlf3tm1a(KOMP)Wtsi/Wtsi

 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
Show

Allelic Composition: Braftm1Mmcm/Braftm1Mmcm,Nkx3-1tm4(cre/ERT2)Mms/Nkx3-1+,Ptentm1Hwu/Pten+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac * C57BL/6

 MP:0005564 increased hemoglobin content "increase in the total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, RGD:Rat Genome Database submission]
Show

Allelic Composition: Chd7tm2a(EUCOMM)Wtsi/Chd7+
Genetic Background: 129S5;B6N-Chd7tm2a(EUCOMM)Wtsi/Wtsi

 MP:0005641 increased mean corpuscular hemoglobin concentration "greater than the normal Hgb/Hct; the average hemoglobin concentration in a given volume of packed red cells, calculated from the hemoglobin therein and the hematocrit, in erythrocyte indices" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:8936]
Show

Allelic Composition: Chd7tm2a(EUCOMM)Wtsi/Chd7+
Genetic Background: 129S5;B6N-Chd7tm2a(EUCOMM)Wtsi/Wtsi

 MP:0005642 decreased mean corpuscular hemoglobin concentration "less than the normal Hgb/Hct; the average hemoglobin concentration in a given volume of packed red cells, calculated from the hemoglobin therein and the hematocrit, in erythrocyte indices" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:8936]
Show

Allelic Composition: Chd7tm2a(EUCOMM)Wtsi/Chd7+
Genetic Background: 129S5;B6N-Chd7tm2a(EUCOMM)Wtsi/Wtsi

 MP:0010093 decreased circulating magnesium level "a reduction in the blood concentration of magnesium" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Cpsf3tm1b(EUCOMM)Wtsi/Cpsf3tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cpsf3tm1b(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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