ENSMUSG00000017715


Mus musculus

Features
Gene ID: ENSMUSG00000017715
  
Biological name :Pgs1
  
Synonyms : CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial / Pgs1 / Q8BHF7
  
Possible biological names infered from orthology : phosphatidylglycerophosphate synthase 1 / Q32NB8
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: E2
Gene start: 117986292
Gene end: 118024011
  
Corresponding Affymetrix probe sets: 10383012 (MoGene1.0st)   1430429_at (Mouse Genome 430 2.0 Array)   1454045_a_at (Mouse Genome 430 2.0 Array)   1454046_x_at (Mouse Genome 430 2.0 Array)   1455229_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000121973
Ensembl peptide - ENSMUSP00000097760
Ensembl peptide - ENSMUSP00000017859
NCBI entrez gene - 74451     See in Manteia.
MGI - MGI:1921701
RefSeq - NM_133757
RefSeq Peptide - NP_598518
swissprot - Q8BHF7
swissprot - B9EKS7
swissprot - F2Z427
swissprot - F8WI04
Ensembl - ENSMUSG00000017715
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pgs1ENSDARG00000075857Danio rerio
 PGS1ENSGALG00000007181Gallus gallus
 PGS1ENSG00000087157Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001736  Phospholipase D/Transphosphatidylase
 IPR016270  CDP-alcohol phosphatidyltransferase class-II family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006655 phosphatidylglycerol biosynthetic process IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0008654 phospholipid biosynthetic process ISS
 biological_processGO:0032049 cardiolipin biosynthetic process IEA
 biological_processGO:0046339 diacylglycerol metabolic process ISS
 cellular_componentGO:0005739 mitochondrion ISS
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008444 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017169 CDP-alcohol phosphatidyltransferase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001303 abnormal lens morphology "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
Show

Allelic Composition: Pdgfrbtm1b(EUCOMM)Hmgu/Pdgfrb+
Genetic Background: C57BL/6N-Pdgfrbtm1b(EUCOMM)Hmgu/H

 MP:0001566 hyperphosphatemia "abnormally high concentrations of phosphates in the circulating blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Pdgfrbtm1b(EUCOMM)Hmgu/Pdgfrb+
Genetic Background: C57BL/6N-Pdgfrbtm1b(EUCOMM)Hmgu/H

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Pdgfrbtm1b(EUCOMM)Hmgu/Pdgfrb+
Genetic Background: C57BL/6N-Pdgfrbtm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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