ENSMUSG00000017801


Mus musculus

Features
Gene ID: ENSMUSG00000017801
  
Biological name :Mlx
  
Synonyms : MAX-like protein X / Mlx
  
Possible biological names infered from orthology : MLX, MAX dimerization protein / Q9UH92
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: D
Gene start: 101087277
Gene end: 101092207
  
Corresponding Affymetrix probe sets: 10381238 (MoGene1.0st)   1418437_a_at (Mouse Genome 430 2.0 Array)   1425930_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000017945
Ensembl peptide - ENSMUSP00000121600
Ensembl peptide - ENSMUSP00000102924
Ensembl peptide - ENSMUSP00000102923
NCBI entrez gene - 21428     See in Manteia.
MGI - MGI:108398
RefSeq - XM_006532809
RefSeq - NM_001159384
RefSeq - NM_001159385
RefSeq - NM_011550
RefSeq Peptide - NP_001152856
RefSeq Peptide - NP_035680
RefSeq Peptide - NP_001152857
swissprot - A2BFB1
swissprot - A2BFB0
swissprot - A2BFA9
swissprot - A2BFB2
Ensembl - ENSMUSG00000017801
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mlxENSDARG00000037891Danio rerio
 MLXENSGALG00000003199Gallus gallus
 MLXENSG00000108788Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mlxipl / Q99MZ3 / Carbohydrate-responsive element-binding protein / Q9NP71* / MLX interacting protein like*ENSMUSG0000000537325
Mlxip / MLX interacting protein / Q9HAP2*ENSMUSG0000003834223


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR032647  Max-like protein X
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
ChREBP activates metabolic gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000005373 Mlxipl / Q99MZ3 / Carbohydrate-responsive element-binding protein / Q9NP71* / MLX interacting protein like*  / complex






 

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