ENSMUSG00000018199


Mus musculus

Features
Gene ID: ENSMUSG00000018199
  
Biological name :Trove2
  
Synonyms : O08848 / Trove2 / TROVE domain family, member 2
  
Possible biological names infered from orthology : P10155
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: F
Gene start: 143750790
Gene end: 143777068
  
Corresponding Affymetrix probe sets: 10358379 (MoGene1.0st)   1423433_at (Mouse Genome 430 2.0 Array)   1436533_at (Mouse Genome 430 2.0 Array)   1436534_at (Mouse Genome 430 2.0 Array)   1436535_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000125623
NCBI entrez gene - 20822     See in Manteia.
MGI - MGI:106652
RefSeq - XM_017319451
RefSeq - NM_013835
RefSeq Peptide - NP_038863
swissprot - O08848
swissprot - Q3TJ75
Ensembl - ENSMUSG00000018199
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trove2ENSDARG00000089225Danio rerio
 TROVE2ENSGALG00000002504Gallus gallus
 P10155ENSG00000116747Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008858  TROVE domain
 IPR036465  von Willebrand factor A-like domain superfamily
 IPR037214  TROVE domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002520 immune system development IMP
 biological_processGO:0007224 smoothened signaling pathway IMP
 biological_processGO:0009411 response to UV IMP
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0060271 cilium assembly IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003723 RNA binding ISO
 molecular_functionGO:0030620 U2 snRNA binding IDA
 molecular_functionGO:0034336 misfolded RNA binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001202 skin photosensitivity "abnormally heightened reactivity of the skin to sunlight " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Trove2tm1Woln/Trove2+
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Wasf2tm1Fwa/Wasf2tm1Fwa
Genetic Background: 129S/SvEv-Wasf2tm1Fwa

 MP:0002494 increased IgM "greater than normal immunoglobulin class M level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Wasf2tm1Fwa/Wasf2tm1Fwa
Genetic Background: 129S/SvEv-Wasf2tm1Fwa

 MP:0002743 glomerulonephritis "glomerular disease characterized by diffuse inflammatory reaction that is not the acute response to infection of the kidneys" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Wasf2tm1Fwa/Wasf2tm1Fwa
Genetic Background: 129S/SvEv-Wasf2tm1Fwa

 MP:0004762 increased anti-double stranded DNA antibody level "increase in the level of antibodies that recognize double stranded DNA" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Wasf2tm1Fwa/Wasf2tm1Fwa
Genetic Background: 129S/SvEv-Wasf2tm1Fwa

 MP:0004771 increased anti-single stranded DNA antibody level "increase in the level of antibodies that recognize single stranded DNA" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Wasf2tm1Fwa/Wasf2tm1Fwa
Genetic Background: 129S/SvEv-Wasf2tm1Fwa

 MP:0004794 increased anti-nuclear antigen antibody level "elevated level of antibodies to nuclear antigens present in the sera" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Wasf2tm1Fwa/Wasf2tm1Fwa
Genetic Background: 129S/SvEv-Wasf2tm1Fwa

Allelic Composition: Trove2tm1Woln/Trove2+
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0004796 increased anti-histone antibody level "elevated level of antibodies to histones present in the sera" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Wasf2tm1Fwa/Wasf2tm1Fwa
Genetic Background: 129S/SvEv-Wasf2tm1Fwa

 MP:0004829 increased anti-chromatin antibody level "increase in the level of antibodies that recognize chromatin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Wasf2tm1Fwa/Wasf2tm1Fwa
Genetic Background: 129S/SvEv-Wasf2tm1Fwa

 MP:0008410 increased cellular sensitivity to ultraviolet irradiation "greater incidence of cell death following exposure to ultraviolet irradiation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Trove2tm1Woln/Trove2+
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0008500 increased IgG2a level "greater than normal immunoglobulin class G2a level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Wasf2tm1Fwa/Wasf2tm1Fwa
Genetic Background: 129S/SvEv-Wasf2tm1Fwa

Allelic Composition: Trove2tm1Woln/Trove2+
Genetic Background: involves: 129S1/Sv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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