ENSMUSG00000018259


Mus musculus

Features
Gene ID: ENSMUSG00000018259
  
Biological name :Prl8a2
  
Synonyms : Prl8a2 / prolactin family 8, subfamily a, member 2
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A3.1
Gene start: 27345673
Gene end: 27354216
  
Corresponding Affymetrix probe sets: 10404316 (MoGene1.0st)   1448608_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000018403
Ensembl peptide - ENSMUSP00000105992
Ensembl peptide - ENSMUSP00000153595
NCBI entrez gene - 13529     See in Manteia.
MGI - MGI:894281
RefSeq - NM_001289919
RefSeq - NM_010088
RefSeq Peptide - NP_001276848
RefSeq Peptide - NP_034218
swissprot - O54832
swissprot - O35258
swissprot - A0A286YDW1
Ensembl - ENSMUSG00000018259
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Prl8a1ENSMUSG0000001975659
Prl8a6 / Q9DAY2 / prolactin family 8, subfamily a, member 6ENSMUSG0000002134553
Prl8a9 / Q9CQ58 / prolactin family8, subfamily a, member 9ENSMUSG0000000649053
Prl8a8 / Q9DAS4 / prolactin family 8, subfamily a, member 81ENSMUSG0000002134651


Protein motifs (from Interpro)
Interpro ID Name
 IPR001400  Somatotropin/prolactin
 IPR009079  Four-helical cytokine-like, core


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IMP
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0060135 maternal process involved in female pregnancy IMP
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005179 hormone activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001126 abnormal ovary morphology "malformed female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
Show

Allelic Composition: Kcnj11Y12stop/Kcnj11Y12stop
Genetic Background: involves: BALB/c * C3H/HeH

 MP:0001712 abnormal placental development "malformed or incomplete differentiation of the organ of metabolic exchange between the fetus and mother" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61790]
Show

Allelic Composition: Kcnj11Y12stop/Kcnj11Y12stop
Genetic Background: involves: BALB/c * C3H/HeH

 MP:0001914 hemorrhage "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Kcnj11Y12stop/Kcnj11Y12stop
Genetic Background: involves: BALB/c * C3H/HeH

 MP:0003845 abnormal decidualization "disrupted proliferation, differentiation or transformation of endometrial stromal cells into decidual cells in the maternal uterus following embryo implantation" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:43609, J:48920]
Show

Allelic Composition: Kcnj11Y12stop/Kcnj11Y12stop
Genetic Background: involves: BALB/c * C3H/HeH

 MP:0005031 abnormal trophoblast "malformation of the mesectodermal cell layer covering the blastocyst that erodes the uterine mucosa and contributes to the formation of the placenta" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Kcnj11Y12stop/Kcnj11Y12stop
Genetic Background: involves: BALB/c * C3H/HeH

 MP:0005033 abnormal trophoblast cells "anomaly of the cells covering the blastocyst that erode the uterine mucosa and contribute to the formation of the placenta " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator, J:57761]
Show

Allelic Composition: Kcnj11Y12stop/Kcnj11Y12stop
Genetic Background: involves: BALB/c * C3H/HeH

 MP:0005164 abnormal response to injury "anomaly in the body s reaction to trauma, especially that by physical means" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Kcnj11Y12stop/Kcnj11Y12stop
Genetic Background: involves: BALB/c * C3H/HeH

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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