ENSMUSG00000018405


Mus musculus

Features
Gene ID: ENSMUSG00000018405
  
Biological name :Mrm1
  
Synonyms : Mrm1 / Q99J25 / rRNA methyltransferase 1, mitochondrial
  
Possible biological names infered from orthology : mitochondrial rRNA methyltransferase 1 / Q6IN84
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: C
Gene start: 84813061
Gene end: 84819515
  
Corresponding Affymetrix probe sets: 10389293 (MoGene1.0st)   1424219_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000018549
NCBI entrez gene - 217038     See in Manteia.
MGI - MGI:2443470
RefSeq - NM_145433
RefSeq Peptide - NP_663408
swissprot - Q99J25
Ensembl - ENSMUSG00000018405
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mrm1ENSDARG00000059658Danio rerio
 MRM1ENSGALG00000039523Gallus gallus
 MRM1ENSG00000278619Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001537  tRNA/rRNA methyltransferase, SpoU type
 IPR004441  RNA methyltransferase TrmH family
 IPR013123  RNA 2-O ribose methyltransferase, substrate binding
 IPR029026  tRNA (guanine-N1-)-methyltransferase, N-terminal
 IPR029028  Alpha/beta knot methyltransferases
 IPR029064  50S ribosomal protein L30e-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000453 enzyme-directed rRNA 2"-O-methylation IBA
 biological_processGO:0006364 rRNA processing IEA
 biological_processGO:0006396 RNA processing IEA
 biological_processGO:0032259 methylation IEA
 cellular_componentGO:0005739 mitochondrion ISO
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008173 RNA methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0070039 rRNA (guanosine-2"-O-)-methyltransferase activity ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Gt(ROSA)26Sortm1(cre/ERT2)Thl/0,Picalmtm1.1Tmae/Picalmtm1.1Tmae
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0013526 increased KLRG1-positive CD4-positive NK T cell number "increase in the number of KLRG1-positive CD4-positive NK T cells, a marker associated with activation" [MGI:Saran]
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Allelic Composition: Gt(ROSA)26Sortm1(cre/ERT2)Thl/0,Picalmtm1.1Tmae/Picalmtm1.1Tmae
Genetic Background: involves: 129 * C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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