ENSMUSG00000018570


Mus musculus

Features
Gene ID: ENSMUSG00000018570
  
Biological name :2810408A11Rik
  
Synonyms : 2810408A11Rik / RIKEN cDNA 2810408A11 gene
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: B3
Gene start: 69897352
Gene end: 69900987
  
Corresponding Affymetrix probe sets: 10387723 (MoGene1.0st)   1430178_at (Mouse Genome 430 2.0 Array)   1453293_a_at (Mouse Genome 430 2.0 Array)   1459803_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000104261
Ensembl peptide - ENSMUSP00000135926
Ensembl peptide - ENSMUSP00000137547
Ensembl peptide - ENSMUSP00000136835
Ensembl peptide - ENSMUSP00000018714
Ensembl peptide - ENSMUSP00000098529
Ensembl peptide - ENSMUSP00000099640
NCBI entrez gene - 70419     See in Manteia.
MGI - MGI:1917669
RefSeq - NM_027419
RefSeq - XM_011249246
RefSeq - XM_006534174
RefSeq - XM_006534172
RefSeq - XM_006534171
RefSeq - NM_001316696
RefSeq - NM_001316697
RefSeq - NM_001316698
RefSeq Peptide - NP_001303625
RefSeq Peptide - NP_001303626
RefSeq Peptide - NP_001303627
RefSeq Peptide - NP_081695
swissprot - B1AR42
swissprot - Q6NSU2
swissprot - B1AR39
swissprot - B1AR44
swissprot - J3QPY8
swissprot - J3QNJ8
Ensembl - ENSMUSG00000018570
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ppp1r2 / Q9DCL8 / protein phosphatase 1, regulatory (inhibitor) subunit 2 / P41236* / PPP1R2B* / PPP1R2 family member B*ENSMUSG0000004771415


Protein motifs (from Interpro)
Interpro ID Name
 IPR007062  Protein phosphatase inhibitor 2 (IPP-2)
 IPR030476  Pentaxin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009966 regulation of signal transduction IEA
 biological_processGO:0032515 negative regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 cellular_componentGO:0000164 protein phosphatase type 1 complex IBA
 molecular_functionGO:0004864 protein phosphatase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
Show

Allelic Composition: Zfp106tm1a(KOMP)Wtsi/Zfp106tm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Zfp106tm1a(KOMP)Wtsi/Wtsi

 MP:0001513 limb grasping "mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: Zfp106tm1a(KOMP)Wtsi/Zfp106tm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Zfp106tm1a(KOMP)Wtsi/Wtsi

 MP:0002833 increased heart weight "greater than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Zfp106tm1a(KOMP)Wtsi/Zfp106tm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Zfp106tm1a(KOMP)Wtsi/Wtsi

 MP:0002896 abnormal bone mineralization "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Zfp106tm1a(KOMP)Wtsi/Zfp106tm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Zfp106tm1a(KOMP)Wtsi/Wtsi

 MP:0003795 abnormal bone structure 
Show

Allelic Composition: Zfp106tm1a(KOMP)Wtsi/Zfp106tm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Zfp106tm1a(KOMP)Wtsi/Wtsi

 MP:0008044 increased NK cell number "greater number of non-T, non-B lymphocytes, having a granular morphology and which are important in innate immunity to viruses and other intracellular pathogens; in addition, these cells can kill certain tumor cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease"]
Show

Allelic Composition: Zfp106tm1a(KOMP)Wtsi/Zfp106tm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Zfp106tm1a(KOMP)Wtsi/Wtsi

 MP:0008045 decreased NK cell number "reduction in the number of non-T, non-B lymphocytes, having a granular morphology and which are important in innate immunity to viruses and other intracellular pathogens; in addition, these cells can kill certain tumor cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease"]
Show

Allelic Composition: Zfp106tm1a(KOMP)Wtsi/Zfp106tm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Zfp106tm1a(KOMP)Wtsi/Wtsi

 MP:0008074 increased CD4-positive T cell number "greater number of the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Zfp106tm1a(KOMP)Wtsi/Zfp106tm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Zfp106tm1a(KOMP)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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