ENSMUSG00000019579


Mus musculus

Features
Gene ID: ENSMUSG00000019579
  
Biological name :Mydgf
  
Synonyms : Mydgf / Myeloid-derived growth factor / Q9CPT4
  
Possible biological names infered from orthology : Q969H8
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: D
Gene start: 56175744
Gene end: 56183920
  
Corresponding Affymetrix probe sets: 10451993 (MoGene1.0st)   1416696_at (Mouse Genome 430 2.0 Array)   1448439_at (Mouse Genome 430 2.0 Array)   1448440_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000019723
NCBI entrez gene - 28106     See in Manteia.
MGI - MGI:2156020
RefSeq - NM_080837
RefSeq Peptide - NP_543027
swissprot - Q9CPT4
Ensembl - ENSMUSG00000019579
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mydgfENSDARG00000071679Danio rerio
 MYDGFENSGALG00000004263Gallus gallus
 MYDGFENSG00000074842Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR018887  Myeloid-derived growth factor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001934 positive regulation of protein phosphorylation IDA
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IDA
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 biological_processGO:0043410 positive regulation of MAPK cascade IDA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0051897 positive regulation of protein kinase B signaling IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000343 altered response to myocardial infarction "change in the physiological response to necrosis of the cardiac tissue, often resulting from the sudden insufficiency of arterial or venous blood supply due to emboli, thrombi or mechanical factors" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Vgftm1Vlcg/Vgf+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac

 MP:0001876 decreased inflammatory response "less than expected response to injury, infection, or insult" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Vgftm1Vlcg/Vgf+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac

 MP:0003037 increased infarction size "increased size of necrotic area from normal of the myocardium resulting from a sudden insufficiency of arterial or venous blood supply due to emboli, thrombi or mechanical factors" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Vgftm1Vlcg/Vgf+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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