ENSMUSG00000019867


Mus musculus

Features
Gene ID: ENSMUSG00000019867
  
Biological name :Gje1
  
Synonyms : gap junction protein, epsilon 1 / Gje1 / Q9CX92
  
Possible biological names infered from orthology : A6NN92
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: A2
Gene start: 14715623
Gene end: 14718214
  
Corresponding Affymetrix probe sets: 10368021 (MoGene1.0st)   1430110_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000020016
NCBI entrez gene - 76743     See in Manteia.
MGI - MGI:1923993
RefSeq - NM_029722
RefSeq Peptide - NP_083998
swissprot - Q9CX92
Ensembl - ENSMUSG00000019867
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR628323.2ENSDARG00000053062Danio rerio
 cx23ENSDARG00000054150Danio rerio
 GJE1ENSG00000203733Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000500  Connexin
 IPR013092  Connexin, N-terminal
 IPR019570  Gap junction protein, cysteine-rich domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000902 cell morphogenesis IMP
 biological_processGO:0002088 lens development in camera-type eye IMP
 biological_processGO:0007154 cell communication IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0035265 organ growth IMP
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005922 connexin complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001292 abnormal lens vesicle development "malformation or abnormal patterning of the lens vesicle of the eye" [J:49424]
Show

Allelic Composition: Gje1Mhdaaey12/Gje1Mhdaaey12
Genetic Background: involves: C3HeB/FeJ

 MP:0001297 microphthalmia "reduced average size of the eyes" [J:18048]
Show

Allelic Composition: Csf3rtm2Eur/Csf3rtm2Eur
Genetic Background: involves: 129P2/OlaHsd * FVB

Allelic Composition: Gje1Mhdaaey12/Gje1+
Genetic Background: involves: C3HeB/FeJ

Allelic Composition: Gje1Mhdaaey12/Gje1Mhdaaey12
Genetic Background: involves: C3HeB/FeJ

 MP:0001303 abnormal lens morphology "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
Show

Allelic Composition: Gje1Mhdaaey12/Gje1+
Genetic Background: involves: C3HeB/FeJ

 MP:0001306 small lens "reduced size of the transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Lgr4Gt(LST020)Byg/Lgr4Gt(LST020)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Gje1Mhdaaey12/Gje1Mhdaaey12
Genetic Background: involves: C3HeB/FeJ

 MP:0001312 abnormal cornea morphology "malformation or absence of the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Lgr4Gt(LST020)Byg/Lgr4Gt(LST020)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001314 corneal opacity "complete or partial clouding of the cornea" [jte:Janan T. Eppig , Mouse Genome Informatics, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Lgr4Gt(LST020)Byg/Lgr4Gt(LST020)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Gje1Mhdaaey12/Gje1Mhdaaey12
Genetic Background: involves: C3HeB/FeJ

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Syne2cpfl8/Syne2cpfl8
Genetic Background: B6.Cg-Syne2cpfl8

 MP:0002840 abnormal lens fibers morphology "structural anomaly of the elongated cells of the crystalline lens of the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Gje1Mhdaaey12/Gje1+
Genetic Background: involves: C3HeB/FeJ

Allelic Composition: Gje1Mhdaaey12/Gje1Mhdaaey12
Genetic Background: involves: C3HeB/FeJ

 MP:0005545 abnormal lens development "aberrant formation of the transparent structure of the eye responsible for focusing light rays" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Gje1Mhdaaey12/Gje1Mhdaaey12
Genetic Background: involves: C3HeB/FeJ

 MP:0010258 polar cataracts "a lens opacity, usually disk-shaped, that is limited to an area in the anterior or posterior pole of the lens capsular region" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", ISBN:978-0-8493-0864-2 "Smith R.S. et al (ed.) Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods"]
Show

Allelic Composition: Gje1Mhdaaey12/Gje1+
Genetic Background: involves: C3HeB/FeJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr