| MP:0000160 | kyphosis | "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0000367 | abnormal coat/ hair morphology | "anomalous color, structure, growth, or texture of the hair" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
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| MP:0000379 | reduced hair follicle number | "fewer number of the epidermal invaginations from which the hair shaft develops" [J:15108] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
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| MP:0000414 | alopecia | "absence of hair or loss of hair; not usually in reference to primary genetic hairlessness but may be due to dietary, stress, secondary to immune condition" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:30772, J:33796] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
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| MP:0000752 | dystrophic muscle | "progressive weakness and wasting of muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67994] |
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Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0001190 | reddish skin | "skin has a more intense ruddy appearance than normal, often due to capillary congestion" [J:65038] |
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Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(KRT14-cre/ERT)20Efu/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * CD-1 * FVB/N
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| MP:0001192 | scaly skin | "skin covered with shedding scales or flakes" [J:65146] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(KRT14-cre/ERT)20Efu/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * CD-1 * FVB/N
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| MP:0001216 | abnormal epidermal layer morphology | "anomalous structure or development of the superficial epithelial portion of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
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| MP:0001219 | thickened epidermis | "increase in the width of the epidermal cell layer in the skin" [J:65146] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(KRT14-cre/ERT)20Efu/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * CD-1 * FVB/N
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| MP:0001239 | abnormal granular layer morphology | "structural or developmental anomaly of the layer of flattened cells containing basophilic granules of keratohyalin and lying just above the stratum spinosum (spiny layer) of the epidermis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0001242 | hyperkeratosis | "increased depth of the corneal layer of the epidermis; thickening of the horny layer of the epidermis" [J:1133] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(KRT14-cre/ERT)20Efu/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * CD-1 * FVB/N
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| MP:0001243 | abnormal dermal layer morphology | "malformed or atypical condition of the dermal layer of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:56777] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(KRT14-cre/ERT)20Efu/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * CD-1 * FVB/N
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| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0001392 | abnormal locomotor activity | "altered ability or inability to move from place to place" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0001672 | abnormal embryogenesis/ development | "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Mapk8ip3tm1.1Ysok/Mapk8ip3tm1.1Ysok
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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| MP:0001694 | failure to form egg cylinders | "inability of inner cell mass cells to grow towards the abembryonic pole to form a cylinder-like structure" [The Atlas of Mouse Development , Revised edition:ISBN 0-12-402035-6, MGI:cls, J:34458] |
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Allelic Composition: Rabl2mot/Rabl2mot
Genetic Background: C57BL/6(CBA)-Rabl2mot
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| MP:0001698 | reduced embryo size | "smaller proportions of embryo compared to littermates" [J:61790] |
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Allelic Composition: Rabl2mot/Rabl2mot
Genetic Background: C57BL/6(CBA)-Rabl2mot
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| MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
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| MP:0001823 | thymus hypoplasia | "small size due to reduced cell number in the thymus" [J:23255] |
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Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0001861 | lung inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the lung" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
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Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0001862 | interstitial pneumonia | "disorder of the lower respiratory tract, primarily affecting the alveolar wall, but may also involve the small airways and blood vessels of the lung parencyma; this is usually inflammatory in nature" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
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| MP:0001874 | acanthosis | "diffuse hyperplasia of the spinous layer of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(KRT14-cre/ERT)20Efu/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * CD-1 * FVB/N
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| MP:0002060 | abnormal skin morphology | "malformation or atypical structure of the membranous protective covering of the body" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:56777] |
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Allelic Composition: Supv3l1tm2.3Jkl/Supv3l1tm2.3Jkl
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0002102 | abnormal ear morphology | "structural or developmental anomaly of any of the structures involved in the ear or vestibular system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
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| MP:0002145 | abnormal T lymphocyte development | "atypical production of or inability to produce mature T cells, and/or accumulation of T cell precursors" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.1Jkl
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6
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| MP:0002269 | muscular atrophy | "a wasting of muscle tissue resulting in a derangement of the muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
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| MP:0002276 | abnormal lung interstitium morphology | "any structural anomaly of the lung tissue, but not including the conducting airways (bronchi, bronchioles, alveoli) " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0003271 | abnormal duodenum morphology | "malformation in the first division of the small intestine that extends from the pyloris to the junction with the jejunum " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0003427 | parakeratosis | "abnormal retention of the nuclei of the keratinocytes in the stratum corneum of the epidermis" [smb:Susan M Bello, Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(KRT14-cre/ERT)20Efu/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * CD-1 * FVB/N
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| MP:0003644 | thymus atrophy | "wasting of the thymus resulting in reduced size " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0003718 | maternal effect | "expression of a phenotypic trait in an female animal s offspring that is dependent on the maternal genotype" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Supv3l1tm1Whle/Supv3l1tm1Whle
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0003935 | abnormal craniofacial development | "anomaly in the process of forming the face and/or cranium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Mapk8ip3tm1.1Ysok/Mapk8ip3tm1.1Ysok
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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| MP:0003984 | embryonic growth retardation | "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Rabl2mot/Rabl2mot
Genetic Background: C57BL/6(CBA)-Rabl2mot
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| MP:0004179 | transmission ratio distortion | "the occurence of an allele or haplotype in the offspring of an organism at skewed Mendelian ratios" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Mapk8ip3tm1.1Ysok/Mapk8ip3tm1.1Ysok
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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| MP:0004778 | increased foam cell number | "greater than normal number of a type of macrophage containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions" [CL:0000517] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0004819 | decreased skeletal muscle mass | "reduction in the physical bulk, or total amount of matter contained within skeletal muscle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0004938 | dilated vasculature | "stretched or widened aperture of the luminal space of the network of tubes that carries blood through the body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(KRT14-cre/ERT)20Efu/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * CD-1 * FVB/N
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| MP:0005089 | decreased double-negative T cell count | "reduced numbers of the subset of T cells found in the thymus that express neither CD4 nor CD8
" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
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Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0005092 | decreased double-positive T cell count | "less than the expected number of the subset of T cells found in the thymus that express both CD4 and CD8" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
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Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0005150 | cachexia | "general weight loss and wasting occurring in the course of chronic disease" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0008075 | decreased CD4-positive T cell number | "reduced number of the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0008079 | decreased CD8-positive T cell number | "reduction in the number of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0008097 | increased plasma cell number | "greater number of terminally differentiated, post-mitotic, short-lived cells of the B cell lineage devoted to producing large amounts of immunoglobulin" [CL:0000786, ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
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| MP:0008770 | decreased survivor rate | "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mapk8ip3tm1.1Ysok/Mapk8ip3tm1.1Ysok
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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| MP:0008844 | decreased subcutaneous adipose tissue amount | "reduction in amount of adipose tissue beneath the skin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0009600 | hypergranulosis | "increased thickness of the granular layer of the epidermis" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
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| MP:0010025 | decreased total body fat amount | "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
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| MP:0011091 | complete prenatal lethality | "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.1Jkl
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6
Allelic Composition: Supv3l1tm2.3Jkl/Supv3l1tm2.3Jkl
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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| MP:0011098 | complete embryonic lethality during organogenesis | "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: Mapk8ip3tm1.1Ysok/Mapk8ip3tm1.1Ysok
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Allelic Composition: Supv3l1tm1Whle/Supv3l1tm1Whle
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0011105 | partial embryonic lethality between implantation and placentation | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the point of implantation and the initiation of placentation (Mus: E4.5 to less than E9)" [MGI:csmith] |
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Allelic Composition: Supv3l1tm1Whle/Supv3l1tm1Whle
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0011108 | partial embryonic lethality during organogenesis | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: Mapk8ip3tm1.1Ysok/Mapk8ip3tm1.1Ysok
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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| MP:0013192 | decreased sebaceous gland number | "fewer than normal numbers of the holocrine glands that secrete sebum into the hair follicles, or in hairless areas into ducts" [MGI:anna] |
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Allelic Composition: Dab1tm1Cpr/Dab1tm6Cpr
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Allelic Composition: Supv3l1tm2Jkl/Supv3l1tm2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
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