ENSMUSG00000020212


Mus musculus

Features
Gene ID: ENSMUSG00000020212
  
Biological name :Mdm1
  
Synonyms : Mdm1 / Q9D067 / transformed mouse 3T3 cell double minute 1
  
Possible biological names infered from orthology : Mdm1 nuclear protein / Q8TC05
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: D2
Gene start: 118141811
Gene end: 118168997
  
Corresponding Affymetrix probe sets: 10366554 (MoGene1.0st)   1445709_at (Mouse Genome 430 2.0 Array)   1451053_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000151424
Ensembl peptide - ENSMUSP00000020437
Ensembl peptide - ENSMUSP00000126258
Ensembl peptide - ENSMUSP00000127919
Ensembl peptide - ENSMUSP00000132966
NCBI entrez gene - 17245     See in Manteia.
MGI - MGI:96951
RefSeq - XM_006513309
RefSeq - NM_001162904
RefSeq - NM_001162905
RefSeq - NM_010785
RefSeq - NM_148922
RefSeq - XM_006513305
RefSeq - XM_006513306
RefSeq - XM_006513307
RefSeq - XM_006513308
RefSeq Peptide - NP_001156376
RefSeq Peptide - NP_034915
RefSeq Peptide - NP_683724
RefSeq Peptide - NP_001156377
swissprot - Q9D067
swissprot - A0A1W2P6V6
swissprot - E9Q0B1
swissprot - E9PW14
swissprot - B2RPU6
Ensembl - ENSMUSG00000020212
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mdm1ENSDARG00000045675Danio rerio
 MDM1ENSGALG00000009905Gallus gallus
 MDM1ENSG00000111554Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR029136  Nuclear protein MDM1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045494 photoreceptor cell maintenance IMP
 biological_processGO:0046600 negative regulation of centriole replication IEA
 biological_processGO:0060041 retina development in camera-type eye IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005814 centriole IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0097730 non-motile cilium IDA
 molecular_functionGO:0008017 microtubule binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001326 retinal degeneration "pathological change in the thin layer of neural tissue lining the back of the eyeball, which contains visual receptors and can result in the impairment or cessation of retinal neural function" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
Show

Allelic Composition: Vac14Gt(RRP155)Byg/Vac14ingls
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

 MP:0003732 abnormal outer plexiform layer morphology "malformation/anomalous structure of the retinal layer that is the site of synapses between the rods and cones (axons) and the horizontal and bipolar cells (dendrites)" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Vac14Gt(RRP155)Byg/Vac14ingls
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

 MP:0003733 abnormal inner nuclear layer morphology "malformation/anomalous structure of the retinal layer which contains the cell bodies of bipolar, horizontal, and amacrine cells" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Vac14Gt(RRP155)Byg/Vac14ingls
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

 MP:0004021 abnormal rod electrophysiology "anomaly in the function of dark adapted vision mediated by the rods" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Vac14Gt(RRP155)Byg/Vac14ingls
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

 MP:0004022 abnormal cone electrophysiology "anomaly in the function of light adapted vision mediated by the cones" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Vac14Gt(RRP155)Byg/Vac14ingls
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

 MP:0005103 abnormal retinal pigmentation "anomalous coloring of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Vac14Gt(RRP155)Byg/Vac14ingls
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

 MP:0005201 abnormal retinal pigment epithelium morphology "anomaly in the epithelial layer of the retina composed of cells containing pigment granules " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Vac14Gt(RRP155)Byg/Vac14ingls
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

 MP:0005549 retinal pigment epithelium hyperplasia "increased numbers of cells in the epithelial layer of the retina composed of cells containing pigment granules " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Vac14Gt(RRP155)Byg/Vac14ingls
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

 MP:0005551 abnormal eye electrophysiology "abnormal function of the eye as determined through electrophysiological recordings from single cells or summary recordings from multiple cells (e.g. electroretinogram)" [NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
Show

Allelic Composition: Vac14Gt(RRP155)Byg/Vac14ingls
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

 MP:0008511 thin retinal inner nuclear layer "reduced thickness of the retinal layer which contains the cell bodies of bipolar, horizontal, and amacrine cells" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Vac14Gt(RRP155)Byg/Vac14ingls
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

 MP:0008515 thin retinal outer nuclear layer "reduced thickness of the retinal layer that contains the nuclei and cell bodies of rods and cones" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Vac14Gt(RRP155)Byg/Vac14ingls
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

 MP:0008587 short photoreceptor outer segment "decreased length of the photoreceptor region that is rich in the visual pigment rhodopsin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Vac14Gt(RRP155)Byg/Vac14ingls
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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