ENSMUSG00000020317


Mus musculus

Features
Gene ID: ENSMUSG00000020317
  
Biological name :Theg
  
Synonyms : Q9JMB1 / Testicular haploid expressed protein / Theg
  
Possible biological names infered from orthology : Q9P2T0 / theg spermatid protein
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: C1
Gene start: 79576379
Gene end: 79587331
  
Corresponding Affymetrix probe sets: 10370573 (MoGene1.0st)   1425244_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000020566
Ensembl peptide - ENSMUSP00000076647
NCBI entrez gene - 21830     See in Manteia.
MGI - MGI:1338756
RefSeq - XM_006513579
RefSeq - NM_011583
RefSeq - NM_199226
RefSeq Peptide - NP_954696
RefSeq Peptide - NP_035713
swissprot - Q9JMB1
Ensembl - ENSMUSG00000020317
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 thegENSDARG00000078644Danio rerio
 THEGENSG00000105549Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006623  Testicular haploid expressed repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0030154 cell differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
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Allelic Composition: Pgrtm2Omc/Pgrtm2Omc
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Thegtm1Wen/Thegtm1Wen
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Mettm1Cpo/Mettm2Cpo
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Thegtm1Wen/Thegtm1Wen
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Thegtm2Wen/Thegtm2Wen
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Thegtm2Wen/Thegtm2Wen
Genetic Background: C3.129-Thegtm2Wen

Allelic Composition: Thegtm2Wen/Theg+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Thegtm2Wen/Theg+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Mettm1Cpo/Mettm2Cpo
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Mettm1Cpo/Mettm2Cpo
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0004901 decreased male germ cell number "reduced numbers of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mettm1Cpo/Mettm2Cpo
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Mettm1Cpo/Mettm2Cpo
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0005578 teratozoospermia "presence of malformed spermatozoa in the semen; malformations include the physical bending of the sperm to produce kinks or bends" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator]
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Allelic Composition: Mettm1Cpo/Mettm2Cpo
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0006380 abnormal spermatid morphology "anomaly in the number or structure of the male germ cells that without further cell division give rise to mature spermatozoa" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mettm1Cpo/Mettm2Cpo
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0008545 absent sperm flagella "mature spermatozoa lack a flagella" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Mettm1Cpo/Mettm2Cpo
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0008892 abnormal sperm flagellum "any strucutral anomaly of the whiplike posterior filiform portion of the spermatozoon that provides sperm motility" [MESH:A05.360.490.890.840]
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Allelic Composition: Mettm1Cpo/Mettm2Cpo
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0009232 abnormal sperm nucleus morphology "any structural abnormality of the sperm head nucleus, including an abnormal nuclear shape or defects in the compaction of nuclear chromatin" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mettm1Cpo/Mettm2Cpo
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0009838 abnormal sperm axoneme morphology "any structural abnormality of the central core of the sperm flagellum, composed of a ring of 9 outer microtubule doublets surrounding a central pair; inner and outer dynein arms project from each of the outer 9 doublets, and these arms are responsible for generating the motive force of the flagellum; in addition, 9 radial spokes, each of which originates from 1 of the 9 outer microtubular doublet pairs, project inward toward the central pair in a helical fashion" [PMID:14581499]
Show

Allelic Composition: Mettm1Cpo/Mettm2Cpo
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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