ENSMUSG00000020332


Mus musculus

Features
Gene ID: ENSMUSG00000020332
  
Biological name :Meikin
  
Synonyms : Meikin / Meiosis-specific kinetochore protein / Q5F2C3
  
Possible biological names infered from orthology : A0A087WXM9 / meiotic kinetochore factor
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B1.3
Gene start: 54370652
Gene end: 54426790
  
Corresponding Affymetrix probe sets: 10376127 (MoGene1.0st)   1454111_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000091745
NCBI entrez gene - 74847     See in Manteia.
MGI - MGI:1922097
RefSeq - NM_029105
RefSeq Peptide - NP_083381
swissprot - Q5F2C3
Ensembl - ENSMUSG00000020332
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000044678Gallus gallus
 MEIKINENSG00000239642Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR034545  Meiosis-specific kinetochore protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007059 chromosome segregation IEA
 biological_processGO:0007060 male meiosis chromosome segregation IMP
 biological_processGO:0010789 meiotic sister chromatid cohesion involved in meiosis I IMP
 biological_processGO:0016321 female meiosis chromosome segregation IMP
 biological_processGO:0045143 homologous chromosome segregation IMP
 biological_processGO:0051321 meiotic cell cycle IEA
 biological_processGO:0051754 meiotic sister chromatid cohesion, centromeric IMP
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IDA
 cellular_componentGO:0000780 condensed nuclear chromosome, centromeric region IDA
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129S4/SvJae

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129S4/SvJae

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
Show

Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129S4/SvJae

 MP:0005168 abnormal female meiosis "malfunction in the process of nuclear division that results in ova with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129S4/SvJae

 MP:0005169 abnormal male meiosis "malfunction in the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129S4/SvJae

 MP:0006380 abnormal spermatid morphology "anomaly in the number or structure of the male germ cells that without further cell division give rise to mature spermatozoa" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129S4/SvJae

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129S4/SvJae

 MP:0009451 abnormal chromosome pairing during meiosis "an anomaly in the highly specific side-by-side association of homologous chromosomes during first prophase of meiosis" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Meikintm1Yow/Meikintm1Yow,Mlh1tm1Lisk/Mlh1tm1Lisk
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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