ENSMUSG00000020547


Mus musculus

Features
Gene ID: ENSMUSG00000020547
  
Biological name :Bzw2
  
Synonyms : Basic leucine zipper and W2 domain-containing protein 2 / Bzw2 / Q91VK1
  
Possible biological names infered from orthology : basic leucine zipper and W2 domains 2 / Q9Y6E2
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: A3
Gene start: 36091835
Gene end: 36158080
  
Corresponding Affymetrix probe sets: 10400030 (MoGene1.0st)   1423456_at (Mouse Genome 430 2.0 Array)   1424608_a_at (Mouse Genome 430 2.0 Array)   1443227_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000020856
Ensembl peptide - ENSMUSP00000152800
Ensembl peptide - ENSMUSP00000152765
Ensembl peptide - ENSMUSP00000152263
Ensembl peptide - ENSMUSP00000152232
Ensembl peptide - ENSMUSP00000152148
NCBI entrez gene - 66912     See in Manteia.
MGI - MGI:1914162
RefSeq - XM_006515166
RefSeq - NM_025840
RefSeq Peptide - NP_080116
swissprot - A0A1Y7VIU9
swissprot - A0A1Y7VM24
swissprot - A0A1Y7VJ43
swissprot - Q91VK1
swissprot - A0A1Y7VKZ4
swissprot - A0A1Y7VM47
Ensembl - ENSMUSG00000020547
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bzw2ENSDARG00000035918Danio rerio
 BZW2ENSGALG00000010809Gallus gallus
 BZW2ENSG00000136261Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Bzw1 / Q9CQC6 / Basic leucine zipper and W2 domain-containing protein 1 / Q7L1Q6* / basic leucine zipper and W2 domains 1*ENSMUSG0000005122371


Protein motifs (from Interpro)
Interpro ID Name
 IPR003307  W2 domain
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0030154 cell differentiation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000062 increased bone density "increased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295]
Show

Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

 MP:0001257 increased body length "increased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

 MP:0003795 abnormal bone structure 
Show

Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

 MP:0003960 increased lean body mass "more than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
Show

Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

 MP:0005559 increased circulating glucose level "greater than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission]
Show

Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

 MP:0010123 increased bone mineral content "elevation in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

 MP:0010507 shortened RR interval "reduction in the length of the interval between an R wave and the next R wave; the RR interval is the inverse of the heart rate" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

 MP:0011396 abnormal sleep behavior "any anomaly in the actions, reactions, or performance of an organism during a periodic, readily reversible state of reduced awareness and metabolic activity" [MGI:smb]
Show

Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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