ENSMUSG00000020840


Mus musculus

Features
Gene ID: ENSMUSG00000020840
  
Biological name :Blmh
  
Synonyms : Bleomycin hydrolase / Blmh / Q8R016
  
Possible biological names infered from orthology : Q13867
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B5
Gene start: 76924809
Gene end: 76987379
  
Corresponding Affymetrix probe sets: 10378802 (MoGene1.0st)   1438961_s_at (Mouse Genome 430 2.0 Array)   1452101_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021197
Ensembl peptide - ENSMUSP00000132739
Ensembl peptide - ENSMUSP00000132608
Ensembl peptide - ENSMUSP00000130370
Ensembl peptide - ENSMUSP00000128505
Ensembl peptide - ENSMUSP00000118243
NCBI entrez gene - 104184     See in Manteia.
MGI - MGI:1345186
RefSeq - NM_178645
RefSeq Peptide - NP_848760
swissprot - E9PYU0
swissprot - E9PY26
swissprot - E9QA53
swissprot - Q8R016
swissprot - E9Q6V3
swissprot - E9PZH4
Ensembl - ENSMUSG00000020840
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 blmhENSDARG00000025977Danio rerio
 BLMHENSGALG00000004259Gallus gallus
 BLMHENSG00000108578Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000169  Cysteine peptidase, cysteine active site
 IPR004134  Peptidase C1B, bleomycin hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0009636 response to toxic substance IMP
 biological_processGO:0042493 response to drug IMP
 biological_processGO:0043418 homocysteine catabolic process IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004177 aminopeptidase activity ISO
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IMP
 molecular_functionGO:0008234 cysteine-type peptidase activity IBA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001192 scaly skin "skin covered with shedding scales or flakes" [J:65146]
Show

Allelic Composition: Zic3Bn/Zic3Bn
Genetic Background: BNT/LeJ

 MP:0001194 dermatitis "inflammation of the skin" [J:65146]
Show

Allelic Composition: Zic3Bn/Zic3Bn
Genetic Background: BNT/LeJ

 MP:0001219 thickened epidermis "increase in the width of the epidermal cell layer in the skin" [J:65146]
Show

Allelic Composition: Zic3Bn/Zic3Bn
Genetic Background: BNT/LeJ

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Zic3Bn/Zic3Bn
Genetic Background: BNT/LeJ

 MP:0002111 abnormal tail morphology "abnormal development of the tail resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Zic3Bn/Zic3Bn
Genetic Background: BNT/LeJ

 MP:0008873 increased sensitivity to xenobiotics "decrease in the dose or concentration of a foreign compound required to induce a specific level of response" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Zic3Bn/Zic3Bn
Genetic Background: BNT/LeJ

 MP:0009766 increased sensitivity to xenobiotic induced morbidity/mortality "decrease in the amount of a foreign compound required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Zic3Bn/Zic3Bn
Genetic Background: BNT/LeJ

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Zic3Bn/Zic3Bn
Genetic Background: BNT/LeJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr