ENSMUSG00000020895


Mus musculus

Features
Gene ID: ENSMUSG00000020895
  
Biological name :Tmem107
  
Synonyms : Q9CPV0 / Tmem107 / Transmembrane protein 107
  
Possible biological names infered from orthology : Q6UX40
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B3
Gene start: 69070806
Gene end: 69073293
  
Corresponding Affymetrix probe sets: 10377418 (MoGene1.0st)   10377429 (MoGene1.0st)   10399428 (MoGene1.0st)   1429058_at (Mouse Genome 430 2.0 Array)   1429059_s_at (Mouse Genome 430 2.0 Array)   1429495_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000075363
Ensembl peptide - ENSMUSP00000091624
NCBI entrez gene - 66910     See in Manteia.
MGI - MGI:1914160
RefSeq - NM_025838
RefSeq - NM_028336
RefSeq Peptide - NP_080114
RefSeq Peptide - NP_082612
swissprot - Q9CPV0
Ensembl - ENSMUSG00000020895
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6NZZ4ENSDARG00000059150Danio rerio
 tmem107lENSDARG00000088398Danio rerio
 Q6UX40ENSG00000179029Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR029248  Transmembrane protein 107


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0021532 neural tube patterning IMP
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0042733 embryonic digit morphogenesis IMP
 biological_processGO:0060271 cilium assembly IEA
 biological_processGO:1904491 protein localization to ciliary transition zone IMP
 biological_processGO:1905515 non-motile cilium assembly IMP
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0035869 ciliary transition zone IEA
 cellular_componentGO:0036038 MKS complex IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000079 abnormal basioccipital bone morphology "malformed basilar process of the occipital bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

 MP:0000080 abnormal exoccipital bone morphology "malformed lateral part of the occipital bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:23837]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

 MP:0000111 cleft palate "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

 MP:0000153 rib bifurcation "forking or division of ribs, may be a result of partial rib fusions" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

 MP:0000358 abnormal cell content/ morphology "structural anomalies of the minute protoplasmic masses that make up organized tissues and which are the fundamental structural and functional units of living organisms" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

 MP:0000432 abnormal head morphology "anomalous structure or development of the portion of the body containing the brain and organs of sight, hearing, taste, and smell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

 MP:0000565 oligodactyly "congenital condition in which some digits or parts of digits are missing" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
Show

Allelic Composition: Smobnb/Smobnb,Tmem107schlei/Tmem107schlei
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

 MP:0000568 ectopic digits "positional abnormality of a digit" [J:50311]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

 MP:0000914 exencephaly "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Ptch1tm1Mps/Ptch1tm1Mps,Tmem107schlei/Tmem107schlei
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3HeB/FeJ * C57BL/6J

Allelic Composition: Smobnb/Smobnb,Tmem107schlei/Tmem107schlei
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

Allelic Composition: Shhtm1Chg/Shhtm1Chg,Tmem107schlei/Tmem107schlei
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3HeB/FeJ * C57BL/6J

 MP:0000925 abnormal floor plate morphology "malformation or absence of a transient group of neuroepithelial cells located at the ventral midline of the neural tube that profoundly influences the development of the vertebrate central nervous system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Smobnb/Smobnb,Tmem107schlei/Tmem107schlei
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

Allelic Composition: Shhtm1Chg/Shhtm1Chg,Tmem107schlei/Tmem107schlei
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3HeB/FeJ * C57BL/6J

Allelic Composition: Gli2tm2.1Alj/Gli2tm2.1Alj,Tmem107schlei/Tmem107schlei
Genetic Background: involves: 129S6/SvEvTac * C3HeB/FeJ * C57BL/6J

Allelic Composition: Gli3Xt-J/Gli3Xt-J,Tmem107schlei/Tmem107schlei
Genetic Background: involves: C3H/HeJ * C3HeB/FeJ * C57BL/6J

 MP:0000926 absent floor plate "missing ventral midline thinning of the developing neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35802]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Tmem107tm1Lex/Tmem107tm1Lex
Genetic Background: B6N.129S5(Cg)-Tmem107tm1Lex/Mmucd

Allelic Composition: Tmem107schlei/Tmem107tm1Lex
Genetic Background: involves: 129S5/SvEvBrd * C3HeB/FeJ * C57BL/6J * C57BL/6N

 MP:0001297 microphthalmia "reduced average size of the eyes" [J:18048]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Ptch1tm1Mps/Ptch1tm1Mps,Tmem107schlei/Tmem107schlei
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3HeB/FeJ * C57BL/6J

 MP:0002151 abnormal neural tube morphology/development "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Tmem107tm1Lex/Tmem107tm1Lex
Genetic Background: B6N.129S5(Cg)-Tmem107tm1Lex/Mmucd

 MP:0003420 delayed intramembranous bone ossification "late onset of bone formation in bones that form without a cartilagenous intermediate including the cranium and clavicle" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

 MP:0003720 abnormal neural tube closure "abnormal invagination and fusion of the neuroepithelial layer in early development" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:99099]
Show

Allelic Composition: Ptch1tm1Mps/Ptch1tm1Mps,Tmem107schlei/Tmem107schlei
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3HeB/FeJ * C57BL/6J

 MP:0004320 split sternum "the appearance of an abnormal division in the long flat bone of the chest which articulates with clavicle and first seven rib pairs" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

 MP:0004321 short sternum "reduced length of the long flat bone of the chest which articulates with clavicle and first seven rib pairs" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

 MP:0004449 absent presphenoid bone "absence of the anterior part of the body of the sphenoid bone in front of the basisphenoid; it is usually a separate bone in the young or fetus, but becomes a part of the sphenoid in the adult" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

 MP:0004451 short presphenoid bone "reduced length of the anterior part of the body of the sphenoid bone in front of the basisphenoid; it is usually a separate bone in the young or fetus, but becomes a part of the sphenoid in the adult" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

 MP:0004462 small basisphenoid bone "reduced size of part of the base of the cranium between the basioccipital and the presphenoid, which usually ossifies separately in the embryo or in the young, and becomes a part of the sphenoid in the adult; in many animals it persists as a separate bone between the basioccipital bone and the presphenoidal bone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

 MP:0004463 basisphenoid bone foramen "the presence of one or more holes in part of the base of the cranium between the basioccipital and the presphenoid, which usually ossifies separately in the embryo or in the young, and becomes a part of the sphenoid in the adult; in many animals it persists as a separate bone between the basioccipital bone and the presphenoidal bone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

 MP:0004574 broad limb buds "increased anterior-posterior width of the mesenchymal outgrowth on the lateral trunk of the embryo that develops into the limbs" [MESH:National Library of Medicine_Medical Subject Headings]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

 MP:0006279 abnormal limb development "anomaly in the formation of the limbs" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

 MP:0009743 preaxial polydactyly "duplication of all or part of the first ray on one or more of the autopods" [PMID:19125433]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Tmem107tm1Lex/Tmem107tm1Lex
Genetic Background: B6N.129S5(Cg)-Tmem107tm1Lex/Mmucd

Allelic Composition: Tmem107schlei/Tmem107tm1Lex
Genetic Background: involves: 129S5/SvEvBrd * C3HeB/FeJ * C57BL/6J * C57BL/6N

 MP:0009883 palatal shelf hypoplasia "reduced size of the palatal projections from the inner part of the maxillary processes that fuse to form the secondary palate, often due to reduced cell number" [PMID:16680722]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Tmem107tm1Lex/Tmem107tm1Lex
Genetic Background: B6N.129S5(Cg)-Tmem107tm1Lex/Mmucd

 MP:0011102 partial embryonic lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

 MP:0011505 camptomelia "a skeletal dysplasia characterized by the bending of the long bones of the extremities" [ISBN:0-683-40008-8]
Show

Allelic Composition: Tff1tm1Mrio/Tff1tm1Mrio
Genetic Background: involves: 129S2/SvPas

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
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