ENSMUSG00000020923


Mus musculus

Features
Gene ID: ENSMUSG00000020923
  
Biological name :Ubtf
  
Synonyms : Ubtf / upstream binding transcription factor, RNA polymerase I
  
Possible biological names infered from orthology : P17480
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: D
Gene start: 102304560
Gene end: 102319742
  
Corresponding Affymetrix probe sets: 10391625 (MoGene1.0st)   1453097_a_at (Mouse Genome 430 2.0 Array)   1460304_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000133611
Ensembl peptide - ENSMUSP00000131930
Ensembl peptide - ENSMUSP00000133844
Ensembl peptide - ENSMUSP00000136310
Ensembl peptide - ENSMUSP00000134665
Ensembl peptide - ENSMUSP00000006754
Ensembl peptide - ENSMUSP00000078539
Ensembl peptide - ENSMUSP00000102732
Ensembl peptide - ENSMUSP00000102734
Ensembl peptide - ENSMUSP00000102736
Ensembl peptide - ENSMUSP00000102740
NCBI entrez gene - 21429     See in Manteia.
MGI - MGI:98512
RefSeq - XM_017314431
RefSeq - XM_011248889
RefSeq - XM_011248891
RefSeq - XM_011248892
RefSeq - XM_017314425
RefSeq - XM_017314426
RefSeq - XM_017314427
RefSeq - XM_017314428
RefSeq - XM_017314429
RefSeq - XM_017314430
RefSeq - NM_001044383
RefSeq - NM_001302954
RefSeq - NM_001302955
RefSeq - NM_011551
RefSeq - XM_011248888
RefSeq Peptide - NP_001037848
RefSeq Peptide - NP_001289883
RefSeq Peptide - NP_001289884
RefSeq Peptide - NP_035681
swissprot - E9Q4A8
swissprot - A2AWT5
swissprot - A2AWT7
swissprot - G3UZW9
swissprot - A2AWT6
Ensembl - ENSMUSG00000020923
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ubtfENSDARG00000035066Danio rerio
 UBTFENSG00000108312Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q3USZ2 / Ubtfl1 / upstream binding transcription factor, RNA polymerase I-like 1 / P0CB47*ENSMUSG0000007450222


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain
 IPR029215  High mobility group box domain 5
 IPR036910  High mobility group box domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001188 RNA polymerase I transcriptional preinitiation complex assembly IEA
 biological_processGO:0006360 transcription by RNA polymerase I IEA
 cellular_componentGO:0001650 fibrillar center IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 molecular_functionGO:0001164 RNA polymerase I CORE element sequence-specific DNA binding IEA
 molecular_functionGO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0097110 scaffold protein binding IEA


Pathways (from Reactome)
Pathway description
RNA Polymerase I Promoter Opening
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase I Chain Elongation
RNA Polymerase I Transcription Termination


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001730 embryonic growth arrest "the cessation of development beyond a particular stage" [J:17509]
Show

Allelic Composition: Usp53mbo/Usp53mbo
Genetic Background: involves: BALB/cByJ * C57BL/6J

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Usp53mbo/Usp53mbo
Genetic Background: involves: BALB/cByJ * C57BL/6J

 MP:0011094 complete embryonic lethality before implantation "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
Show

Allelic Composition: Usp53mbo/Usp53mbo
Genetic Background: involves: BALB/cByJ * C57BL/6J

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Usp53mbo/Usp53mbo
Genetic Background: involves: BALB/cByJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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