ENSMUSG00000021114


Mus musculus

Features
Gene ID: ENSMUSG00000021114
  
Biological name :Atp6v1d
  
Synonyms : Atp6v1d / ATPase, H+ transporting, lysosomal V1 subunit D / P57746
  
Possible biological names infered from orthology : ATPase H+ transporting V1 subunit D / Q9Y5K8
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: C3
Gene start: 78840725
Gene end: 78861638
  
Corresponding Affymetrix probe sets: 10401138 (MoGene1.0st)   1416951_a_at (Mouse Genome 430 2.0 Array)   1416952_at (Mouse Genome 430 2.0 Array)   1438993_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021536
NCBI entrez gene - 73834     See in Manteia.
MGI - MGI:1921084
RefSeq - NM_023721
RefSeq Peptide - NP_076210
swissprot - P57746
swissprot - Q3U861
Ensembl - ENSMUSG00000021114
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atp6v1dENSDARG00000011175Danio rerio
 ATP6V1DENSGALG00000009570Gallus gallus
 Q9Y5K8ENSG00000100554Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002699  ATPase, V1 complex, subunit D


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0060271 cilium assembly IEA
 biological_processGO:0061512 protein localization to cilium IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0033176 proton-transporting V-type ATPase complex IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IEA


Pathways (from Reactome)
Pathway description
ROS, RNS production in phagocytes
Neutrophil degranulation
Insulin receptor recycling
Transferrin endocytosis and recycling
Ion channel transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
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Allelic Composition: Atp1a3tm1b(EUCOMM)Hmgu/Atp1a3+
Genetic Background: C57BL/6N-Atp1a3tm1b(EUCOMM)Hmgu/H

 MP:0001539 decreased number of caudal vertebrae "reduced number of the bony segments of the tail" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Atp1a3tm1b(EUCOMM)Hmgu/Atp1a3+
Genetic Background: C57BL/6N-Atp1a3tm1b(EUCOMM)Hmgu/H

 MP:0005505 increased platelet count "greater than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Atp1a3tm1b(EUCOMM)Hmgu/Atp1a3+
Genetic Background: C57BL/6N-Atp1a3tm1b(EUCOMM)Hmgu/H

 MP:0008935 decreased mean platelet volume "reduced average content of platelet cells over normal" [MGI:mberry "Melissa Berry, Genetics Resources Curator"]
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Allelic Composition: Atp1a3tm1b(EUCOMM)Hmgu/Atp1a3+
Genetic Background: C57BL/6N-Atp1a3tm1b(EUCOMM)Hmgu/H

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Atp1a3tm1b(EUCOMM)Hmgu/Atp1a3+
Genetic Background: C57BL/6N-Atp1a3tm1b(EUCOMM)Hmgu/H

Allelic Composition: Atp6v1dtm1b(EUCOMM)Hmgu/Atp6v1dtm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Atp6v1dtm1b(EUCOMM)Hmgu/Tcp

 MP:0013292 embryonic lethality prior to organogenesis "death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb]
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Allelic Composition: Atp6v1dtm1b(EUCOMM)Hmgu/Atp6v1dtm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Atp6v1dtm1b(EUCOMM)Hmgu/Tcp

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
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Allelic Composition: Atp6v1dtm1b(EUCOMM)Hmgu/Atp6v1dtm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Atp6v1dtm1b(EUCOMM)Hmgu/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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