ENSMUSG00000021268


Mus musculus

Features
Gene ID: ENSMUSG00000021268
  
Biological name :Meg3
  
Synonyms : Meg3
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: F1
Gene start: 109541001
Gene end: 109571726
  
Corresponding Affymetrix probe sets: 10398326 (MoGene1.0st)   10398332 (MoGene1.0st)   1426758_s_at (Mouse Genome 430 2.0 Array)   1428764_at (Mouse Genome 430 2.0 Array)   1428765_at (Mouse Genome 430 2.0 Array)   1429256_at (Mouse Genome 430 2.0 Array)   1429257_at (Mouse Genome 430 2.0 Array)   1436057_at (Mouse Genome 430 2.0 Array)   1436713_s_at (Mouse Genome 430 2.0 Array)   1439380_x_at (Mouse Genome 430 2.0 Array)   1452183_a_at (Mouse Genome 430 2.0 Array)   1452905_at (Mouse Genome 430 2.0 Array)   1452906_at (Mouse Genome 430 2.0 Array)   
  
Cross references: NCBI entrez gene - 17263     See in Manteia.
MGI - MGI:1202886
Ensembl - ENSMUSG00000021268
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
No match


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000733 abnormal muscle development "anomalous differentiation of muscle tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Tyrc-m/Tyrc-m
Genetic Background: involves: 101/H * C3H/HeH

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Nle1tm1Cba/Nle1tm1Cba
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL/J

Allelic Composition: Meg3Gt(pGTi)216Gos/Meg3+
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Meg3Gt(pGTi)216Gos/Meg3Gt(pGTi)216Gos
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Meg3Gt(pGTi)216Gos/Meg3+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Meg3tm1Kono/Meg3+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N * DBA/2

Allelic Composition: Meg3tm1Kono/Meg3tm1Kono
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N * DBA/2

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Nle1tm1Cba/Nle1tm1Cba
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL/J

Allelic Composition: Meg3Gt(pGTi)216Gos/Meg3+
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Meg3Gt(pGTi)216Gos/Meg3Gt(pGTi)216Gos
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Meg3Gt(pGTi)216Gos/Meg3+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Meg3tm1Jvs/Meg3+
Genetic Background: involves: 129P2/OlaHsd

 MP:0001654 hepatic necrosis "pathologic death of cells within, or a portion of, the liver" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Meg3tm1Kono/Meg3+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N * DBA/2

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Meg3tm1Kono/Meg3+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N * DBA/2

 MP:0001953 respiratory failure "cessation of or failure to commence breathing" [MGI:cls, J:60159]
Show

Allelic Composition: Tyrc-m/Tyrc-m
Genetic Background: involves: 101/H * C3H/HeH

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Meg3Gt(pGTi)216Gos/Meg3+
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Meg3Gt(pGTi)216Gos/Meg3Gt(pGTi)216Gos
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Meg3Gt(pGTi)216Gos/Meg3+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Dgat1tm2Far/Dgat1tm2Far,Tg(KRT14-cre)1Amc/?
Genetic Background: involves: 129S4/SvJae * C57BL/6 * CBA

 MP:0002270 abnormal alveoli morphology "any structural anomaly of the outpouching of the respiratory system where gas exchange occurs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Meg3tm1Kono/Meg3+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N * DBA/2

 MP:0002427 dwarfism "abnormally undersized with disproportionate body parts" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nle1tm1Cba/Nle1tm1Cba
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL/J

 MP:0003084 abnormal skeletal muscle fiber morphology "anomalous structure of the skeletal muscle fibers, the large multinucleated cells that make up the skeletal muscles" [smb:Susan M. Bello, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Tyrc-m/Tyrc-m
Genetic Background: involves: 101/H * C3H/HeH

 MP:0003122 maternal imprinting "specific loci are inactivated during oogenesis and are not expressed in offspring" [llw2:Linda Washburn, Mouse Genome Informatics Curator, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Meg3Gt(pGTi)216Gos/Meg3+
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Meg3tm1Jvs/Meg3+
Genetic Background: involves: 129P2/OlaHsd

 MP:0003123 paternal imprinting "specific loci are inactivated during spermatogenesis and are not expressed in offspring " [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator, llw2:Linda Washburn, Mouse Genome Informatics Curator]
Show

Allelic Composition: Tyrc-m/Tyrc-m
Genetic Background: involves: 101/H * C3H/HeH

 MP:0003787 abnormal imprinting "defect in the normal inactivation of specific loci during gametogenesis" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nle1tm1Cba/Nle1tm1Cba
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL/J

Allelic Composition: Meg3Gt(pGTi)216Gos/Meg3+
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Meg3Gt(pGTi)216Gos/Meg3Gt(pGTi)216Gos
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Meg3Gt(pGTi)216Gos/Meg3+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Meg3tm1Jvs/Meg3+
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Meg3tm1Itl/Meg3+
Genetic Background: B6.129S6-Meg3tm1Itl

 MP:0004201 fetal growth retardation "slow or limited development during the fetal period (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nle1tm1Cba/Nle1tm1Cba
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL/J

Allelic Composition: Meg3Gt(pGTi)216Gos/Meg3+
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Meg3Gt(pGTi)216Gos/Meg3Gt(pGTi)216Gos
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Meg3Gt(pGTi)216Gos/Meg3+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004921 decreased placenta weight "reduction in the weight of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Meg3tm1Itl/Meg3+
Genetic Background: B6.129S6-Meg3tm1Itl

 MP:0008770 decreased survivor rate "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Meg3tm1Kono/Meg3+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N * DBA/2

 MP:0009431 decreased fetal weight "reduced weight of a fetus compared to controls (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Meg3tm1Itl/Meg3+
Genetic Background: B6.129S6-Meg3tm1Itl

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Meg3tm1Jvs/Meg3+
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Meg3tm1Kono/Meg3+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N * DBA/2

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Meg3Gt(pGTi)216Gos/Meg3+
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

 MP:0011089 complete perinatal lethality "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
Show

Allelic Composition: Tyrc-m/Tyrc-m
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Meg3tm1Itl/Meg3+
Genetic Background: B6.129S6-Meg3tm1Itl

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Meg3tm1Kono/Meg3+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N * DBA/2

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
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