ENSMUSG00000021294


Mus musculus

Features
Gene ID: ENSMUSG00000021294
  
Biological name :Kif26a
  
Synonyms : Kif26a / Kinesin-like protein KIF26A / Q52KG5
  
Possible biological names infered from orthology : kinesin family member 26A / Q9ULI4
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: F1
Gene start: 112146208
Gene end: 112181747
  
Corresponding Affymetrix probe sets: 10398814 (MoGene1.0st)   1447933_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000119482
NCBI entrez gene - 668303     See in Manteia.
MGI - MGI:2447072
RefSeq - NM_001097621
RefSeq - XM_006516162
RefSeq Peptide - NP_001091090
swissprot - Q52KG5
Ensembl - ENSMUSG00000021294
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kif26aaENSDARG00000042368Danio rerio
 kif26abENSDARG00000015016Danio rerio
 KIF26AENSGALG00000011581Gallus gallus
 KIF26AENSG00000066735Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kif26b / Q7TNC6 / Kinesin-like protein KIF26B / Q2KJY2* / kinesin family member 26B*ENSMUSG0000002649443


Protein motifs (from Interpro)
Interpro ID Name
 IPR001752  Kinesin motor domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027640  Kinesin-like protein
 IPR036961  Kinesin motor domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001560 regulation of cell growth by extracellular stimulus IMP
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0009968 negative regulation of signal transduction IMP
 biological_processGO:0048484 enteric nervous system development IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005871 kinesin complex IBA
 cellular_componentGO:0005874 microtubule IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IDA


Pathways (from Reactome)
Pathway description
MHC class II antigen presentation
COPI-dependent Golgi-to-ER retrograde traffic
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000495 abnormal colon morphology "malformation of the portion of the large intestine between the cecum and the rectum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Rb1tm2.1Brn/Rb1tm2.1Brn
Genetic Background: Not Specified

 MP:0001045 abnormal enteric ganglia morphology "any strucutural anomaly or deformity of the groups of nerve cell bodies associated with the enteric neurons" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Rb1tm2.1Brn/Rb1tm2.1Brn
Genetic Background: Not Specified

 MP:0001046 abnormal enteric neuron morphology "malformed or absent neurons that innervate the esophagus, stomach, small and large bowel" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Rb1tm2.1Brn/Rb1tm2.1Brn
Genetic Background: Not Specified

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Rb1tm2.1Brn/Rb1tm2.1Brn
Genetic Background: Not Specified

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Rb1tm2.1Brn/Rb1tm2.1Brn
Genetic Background: Not Specified

 MP:0002731 megacolon "extreme dilation of the colon" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:40722]
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Allelic Composition: Rb1tm2.1Brn/Rb1tm2.1Brn
Genetic Background: Not Specified

 MP:0003289 abnormal intestinal peristalsis "altered intestinal movement characterized by waves of alternate circular contraction and relaxation of the muscular walls of the bowel that move bowel contents forward" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Rb1tm2.1Brn/Rb1tm2.1Brn
Genetic Background: Not Specified

 MP:0003651 abnormal axon outgrowth "defect/abnormality in the ability of an axon to extend from a neuron cell body" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:96121]
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Allelic Composition: Rb1tm2.1Brn/Rb1tm2.1Brn
Genetic Background: Not Specified

 MP:0004948 abnormal neuronal precursor proliferation "any anomaly in the ability of a neuroblast population to undergo rapid expansion by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rb1tm2.1Brn/Rb1tm2.1Brn
Genetic Background: Not Specified

 MP:0005150 cachexia "general weight loss and wasting occurring in the course of chronic disease" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Rb1tm2.1Brn/Rb1tm2.1Brn
Genetic Background: Not Specified

 MP:0008874 decreased sensitivity to xenobiotics "increase in the dose or concentration of a foreign compound required to induce a specific level of response" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Rb1tm2.1Brn/Rb1tm2.1Brn
Genetic Background: Not Specified

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Rb1tm2.1Brn/Rb1tm2.1Brn
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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