ENSMUSG00000021361


Mus musculus

Features
Gene ID: ENSMUSG00000021361
  
Biological name :Tmem14c
  
Synonyms : Q9CQN6 / Tmem14c / transmembrane protein 14C
  
Possible biological names infered from orthology : AL024498.2 / Q9NUH8 / Q9P0S9 / TMEM14B / transmembrane protein 14B
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A3.3
Gene start: 41016292
Gene end: 41022586
  
Corresponding Affymetrix probe sets: 10404731 (MoGene1.0st)   1416479_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021790
NCBI entrez gene - 66154     See in Manteia.
MGI - MGI:1913404
RefSeq - XM_006516939
RefSeq - NM_025387
RefSeq - XM_006516937
RefSeq - XM_006516938
RefSeq Peptide - NP_079663
swissprot - Q9CQN6
Ensembl - ENSMUSG00000021361
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmem14caENSDARG00000110836Danio rerio
 tmem14cbENSDARG00000114991Danio rerio
 ENSGALG00000034591Gallus gallus
 TMEM14CLENSGALG00000036713Gallus gallus
 AL024498.2ENSG00000272162Homo sapiens
 Q9NUH8ENSG00000137210Homo sapiens
 Q9P0S9ENSG00000111843Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P56983 / Tmem14a / transmembrane protein 14A / Q9Y6G1*ENSMUSG0000002593346


Protein motifs (from Interpro)
Interpro ID Name
 IPR005349  TMEM14 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006783 heme biosynthetic process IEA
 biological_processGO:0006839 mitochondrial transport IMP
 biological_processGO:0030218 erythrocyte differentiation IMP
 biological_processGO:0070453 regulation of heme biosynthetic process IMP
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000245 abnormal erythropoiesis "atypical process of red blood cell formation" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator]
Show

Allelic Composition: Unc93b1tm1(KOMP)Vlcg/Unc93b1tm1(KOMP)Vlcg
Genetic Background: involves: C57BL/6NTac

 MP:0000603 pale liver "liver lacking normal coloration, often refers to bloodless condition" [J:18048]
Show

Allelic Composition: Unc93b1tm1(KOMP)Vlcg/Unc93b1tm1(KOMP)Vlcg
Genetic Background: involves: C57BL/6NTac

 MP:0001577 anemia "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
Show

Allelic Composition: Unc93b1tm1(KOMP)Vlcg/Unc93b1tm1(KOMP)Vlcg
Genetic Background: involves: C57BL/6NTac

 MP:0001588 hemoglobin abnormalities "defects in the levels or the function of the oxygen-carrying protein of erythrocytes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Unc93b1tm1(KOMP)Vlcg/Unc93b1tm1(KOMP)Vlcg
Genetic Background: involves: C57BL/6NTac

 MP:0006207 embryonic lethality during organogenesis "death anytime after embryo turning but before the completion of organogenesis (E9 to less than E14)" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Unc93b1tm1(KOMP)Vlcg/Unc93b1tm1(KOMP)Vlcg
Genetic Background: involves: C57BL/6NTac

 MP:0008956 decreased cellular hemoglobin content "decrease in the mean of the red blood cell hemoglobin concentration (RBC CH) histogram, which represents the distribution of red blood cells by the amount of hemoglobin present in each individual cell independent of cell volume" [MGI:brs "Beverly Richards-Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Unc93b1tm1(KOMP)Vlcg/Unc93b1tm1(KOMP)Vlcg
Genetic Background: involves: C57BL/6NTac

 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Unc93b1tm1(KOMP)Vlcg/Unc93b1tm1(KOMP)Vlcg
Genetic Background: involves: C57BL/6NTac

 MP:0011108 partial embryonic lethality during organogenesis "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Unc93b1tm1(KOMP)Vlcg/Unc93b1tm1(KOMP)Vlcg
Genetic Background: involves: C57BL/6NTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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