ENSMUSG00000021395


Mus musculus

Features
Gene ID: ENSMUSG00000021395
  
Biological name :Spin1
  
Synonyms : Mus musculus spindlin 1 (Spin1), transcript variant 1, mRNA. / Q61142 / Spin1
  
Possible biological names infered from orthology : Q9Y657 / spindlin 1
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A5
Gene start: 51100880
Gene end: 51152546
  
Corresponding Affymetrix probe sets: 10405163 (MoGene1.0st)   1415794_a_at (Mouse Genome 430 2.0 Array)   1415795_at (Mouse Genome 430 2.0 Array)   1436809_a_at (Mouse Genome 430 2.0 Array)   1460164_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000093473
NCBI entrez gene - 20729     See in Manteia.
MGI - MGI:109242
RefSeq - NM_001283030
RefSeq - NM_011462
RefSeq - NM_146043
RefSeq - XM_017315469
RefSeq - NM_001283028
RefSeq - NM_001283029
RefSeq - XM_006516893
RefSeq - XM_006516894
RefSeq Peptide - NP_035592
RefSeq Peptide - NP_666155
RefSeq Peptide - NP_001269957
RefSeq Peptide - NP_001269958
RefSeq Peptide - NP_001269959
swissprot - Q61142
Ensembl - ENSMUSG00000021395
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q90WG1ENSGALG00000014916Gallus gallus
 Q90WG2ENSGALG00000040704Gallus gallus
 SPIN1ENSG00000106723Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Spin4 / Q8K1L2 / Spindlin-4 / Q56A73* / spindlin family member 4*ENSMUSG0000007172269
Q6NVE3 / Spin2c / Spindlin-2C ENSMUSG0000004655069
Spin2d / Q9BPZ2* / SPIN2A* / SPIN2B* / Q99865* / spindlin family member 2A* / spindlin family member 2B*ENSMUSG0000007956650
Spin2f / Q9BPZ2* / SPIN2A* / SPIN2B* / Q99865* / spindlin family member 2A* / spindlin family member 2B*ENSMUSG0000009575450
Gm21425 / Q99865* / Q9BPZ2* / SPIN2A* / SPIN2B* / spindlin family member 2A* / spindlin family member 2B*ENSMUSG0000009682049
Gm20777 / Q99865* / Q9BPZ2* / SPIN2A* / SPIN2B* / spindlin family member 2A* / spindlin family member 2B*ENSMUSG0000009481349
Gm20737 / Q99865* / Q9BPZ2* / SPIN2A* / SPIN2B* / spindlin family member 2A* / spindlin family member 2B*ENSMUSG0000009595049
Gm20831 / Q99865* / Q9BPZ2* / SPIN2A* / SPIN2B* / spindlin family member 2A* / spindlin family member 2B*ENSMUSG0000009432549
Gm21440 / Q99865* / Q9BPZ2* / SPIN2A* / SPIN2B* / spindlin family member 2A* / spindlin family member 2B*ENSMUSG0000010346849
Gm21310 / Q99865* / Q9BPZ2* / SPIN2A* / SPIN2B* / spindlin family member 2A* / spindlin family member 2B*ENSMUSG0000009503249
Gm20795 / Q99865* / Q9BPZ2* / SPIN2A* / SPIN2B* / spindlin family member 2A* / spindlin family member 2B*ENSMUSG0000009545249
Gm20807 / Q99865* / Q9BPZ2* / SPIN2A* / SPIN2B* / spindlin family member 2A* / spindlin family member 2B*ENSMUSG0000010426749
Spin2e / Q9BPZ2* / SPIN2A* / SPIN2B* / Q99865* / spindlin family member 2A* / spindlin family member 2B*ENSMUSG0000009664549
Gm20773 / Q99865* / Q9BPZ2* / SPIN2A* / SPIN2B* / spindlin family member 2A* / spindlin family member 2B*ENSMUSG0000009590049
Gm20772 / Q99865* / Q9BPZ2* / SPIN2A* / SPIN2B* / spindlin family member 2A* / spindlin family member 2B*ENSMUSG0000010273949
Gm20747 / Mus musculus predicted, 20868 (Gm20868), mRNA. / Q99865* / Q9BPZ2* / SPIN2A* / SPIN2B* / spindlin family member 2A* / spindlin family member 2B*ENSMUSG0000009472948
Gm5926 / Q99865* / Q9BPZ2* / SPIN2A* / SPIN2B* / spindlin family member 2A* / spindlin family member 2B*ENSMUSG0000009460148
Gm21637 / Mus musculus spindlin family, member 2, pseudo 1 (Spin2-ps1), mRNA. / Q99865* / Q9BPZ2* / SPIN2A* / SPIN2B* / spindlin family member 2A* / spindlin family member 2B*ENSMUSG0000009577048
Gm20909 / Mus musculus predicted, 20868 (Gm20868), mRNA. / Q99865* / Q9BPZ2* / SPIN2A* / SPIN2B* / spindlin family member 2A* / spindlin family member 2B*ENSMUSG0000009429448
Gm20917 / Q99865* / Q9BPZ2* / SPIN2A* / SPIN2B* / spindlin family member 2A* / spindlin family member 2B*ENSMUSG0000009586748


Protein motifs (from Interpro)
Interpro ID Name
 IPR003671  Spindlin/spermiogenesis-specific protein
 IPR029565  Spindlin-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007143 female meiotic nuclear division IC
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007276 gamete generation IEA
 biological_processGO:0009303 rRNA transcription IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030177 positive regulation of Wnt signaling pathway IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0051321 meiotic cell cycle IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005819 spindle IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0035064 methylated histone binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0010767 abnormal female meiosis I arrest "any anomaly in the process in which oocytes stop at the diplotene stage of meiosis I and lie dormant, often for long periods of time" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Shhtm1(EGFP/cre)Cjt/Shh+
Genetic Background: involves: 129X1/SvJ

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Shhtm1(EGFP/cre)Cjt/Shh+
Genetic Background: involves: 129X1/SvJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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