ENSMUSG00000021519


Mus musculus

Features
Gene ID: ENSMUSG00000021519
  
Biological name :Mterf3
  
Synonyms : Mterf3 / Q8R3J4 / Transcription termination factor 3, mitochondrial
  
Possible biological names infered from orthology : mitochondrial transcription termination factor 3 / Q96E29
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: B3
Gene start: 66906968
Gene end: 66933088
  
Corresponding Affymetrix probe sets: 10410264 (MoGene1.0st)   1454116_a_at (Mouse Genome 430 2.0 Array)   1459262_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000152951
Ensembl peptide - ENSMUSP00000134032
Ensembl peptide - ENSMUSP00000134286
Ensembl peptide - ENSMUSP00000021991
Ensembl peptide - ENSMUSP00000133330
Ensembl peptide - ENSMUSP00000133433
Ensembl peptide - ENSMUSP00000133456
Ensembl peptide - ENSMUSP00000133594
Ensembl peptide - ENSMUSP00000133596
NCBI entrez gene - 66410     See in Manteia.
MGI - MGI:1913660
RefSeq - XM_017315563
RefSeq - NM_025547
RefSeq - XM_006517321
RefSeq - XM_006517322
RefSeq - XM_011244548
RefSeq Peptide - NP_079823
swissprot - G3UWK8
swissprot - A0A286YCF0
swissprot - Q8R3J4
swissprot - G3UWV0
swissprot - G3UWX0
swissprot - G3UX91
swissprot - G3UYZ7
swissprot - G3UYC7
Ensembl - ENSMUSG00000021519
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mterf3ENSDARG00000003207Danio rerio
 MTERF3ENSGALG00000040511Gallus gallus
 MTERF3ENSG00000156469Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003690  Transcription termination factor, mitochondrial/chloroplastic


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0008380 RNA splicing IBA
 biological_processGO:0032502 developmental process IBA
 biological_processGO:0042254 ribosome biogenesis IEA
 biological_processGO:0042255 ribosome assembly IBA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005739 mitochondrion ISO
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IEA
 molecular_functionGO:0003727 single-stranded RNA binding IBA
 molecular_functionGO:0019843 rRNA binding IBA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA


Pathways (from Reactome)
Pathway description
Pink/Parkin Mediated Mitophagy


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000274 enlarged heart "increase over normal size of the heart" [J:29971]
Show

Allelic Composition: Prkdcscid/Prkdcscid,Tg(Tcrb)93Vbo/0
Genetic Background: involves: C57BL/Lia * CB17 * CBA/BrA

 MP:0000278 abnormal myocardial fiber morphology "malformed or poorly developed cardiac muscle fibers, the multinucleated muscle cells of the heart" [J:18048]
Show

Allelic Composition: Prkdcscid/Prkdcscid,Tg(Tcrb)93Vbo/0
Genetic Background: involves: C57BL/Lia * CB17 * CBA/BrA

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Prkdcscid/Prkdcscid,Tg(Tcrb)93Vbo/0
Genetic Background: involves: C57BL/Lia * CB17 * CBA/BrA

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Prkdcscid/Prkdcscid,Tg(Tcrb)93Vbo/0
Genetic Background: involves: C57BL/Lia * CB17 * CBA/BrA

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Prkdcscid/Prkdcscid,Tg(Tcrb)93Vbo/0
Genetic Background: involves: C57BL/Lia * CB17 * CBA/BrA

 MP:0005330 cardiomyopathy "diseases of the heart (myocardium); may result from many causes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:80681]
Show

Allelic Composition: Prkdcscid/Prkdcscid,Tg(Tcrb)93Vbo/0
Genetic Background: involves: C57BL/Lia * CB17 * CBA/BrA

 MP:0006036 abnormal mitochondrial physiology 
Show

Allelic Composition: Prkdcscid/Prkdcscid,Tg(Tcrb)93Vbo/0
Genetic Background: involves: C57BL/Lia * CB17 * CBA/BrA

 MP:0010956 abnormal mitochondrial ATP synthesis coupled electron transport "anomaly in the transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane and mediated by multisubunit enzyme complexes known as complex I-IV" [GO:0042775, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Prkdcscid/Prkdcscid,Tg(Tcrb)93Vbo/0
Genetic Background: involves: C57BL/Lia * CB17 * CBA/BrA

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Prkdcscid/Prkdcscid,Tg(Tcrb)93Vbo/0
Genetic Background: involves: C57BL/Lia * CB17 * CBA/BrA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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