ENSMUSG00000021557


Mus musculus

Features
Gene ID: ENSMUSG00000021557
  
Biological name :Agtpbp1
  
Synonyms : Agtpbp1 / Cytosolic carboxypeptidase 1 / Q641K1
  
Possible biological names infered from orthology : ATP/GTP binding protein 1 / Q9UPW5
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: B2
Gene start: 59445742
Gene end: 59585227
  
Corresponding Affymetrix probe sets: 10409737 (MoGene1.0st)   1418332_a_at (Mouse Genome 430 2.0 Array)   1429933_at (Mouse Genome 430 2.0 Array)   1432385_a_at (Mouse Genome 430 2.0 Array)   1458310_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000129846
Ensembl peptide - ENSMUSP00000153638
Ensembl peptide - ENSMUSP00000153569
Ensembl peptide - ENSMUSP00000153032
Ensembl peptide - ENSMUSP00000132854
Ensembl peptide - ENSMUSP00000132697
Ensembl peptide - ENSMUSP00000131627
Ensembl peptide - ENSMUSP00000131322
Ensembl peptide - ENSMUSP00000130939
Ensembl peptide - ENSMUSP00000130037
Ensembl peptide - ENSMUSP00000130030
Ensembl peptide - ENSMUSP00000022040
Ensembl peptide - ENSMUSP00000105456
Ensembl peptide - ENSMUSP00000126238
Ensembl peptide - ENSMUSP00000127460
Ensembl peptide - ENSMUSP00000127600
Ensembl peptide - ENSMUSP00000128552
Ensembl peptide - ENSMUSP00000128589
Ensembl peptide - ENSMUSP00000129135
Ensembl peptide - ENSMUSP00000129686
NCBI entrez gene - 67269     See in Manteia.
MGI - MGI:2159437
RefSeq - XM_011244557
RefSeq - XM_011244556
RefSeq - XM_011244555
RefSeq - XM_006517342
RefSeq - XM_006517340
RefSeq - XM_006517339
RefSeq - XM_006517338
RefSeq - XM_006517337
RefSeq - XM_006517336
RefSeq - XM_006517335
RefSeq - NM_001048008
RefSeq - NM_001284218
RefSeq - NM_001284219
RefSeq - NM_023328
RefSeq - NM_001284221
RefSeq Peptide - NP_001041473
RefSeq Peptide - NP_001271147
RefSeq Peptide - NP_001271148
RefSeq Peptide - NP_001271150
RefSeq Peptide - NP_075817
swissprot - E9Q3T5
swissprot - Q641K1
swissprot - Q8C1R2
swissprot - F6ZCF0
swissprot - A0A286YCK8
swissprot - A0A286YDV2
swissprot - A0A286YDY7
swissprot - E9PX07
swissprot - E9PXA7
swissprot - E9Q878
swissprot - E9PYF9
swissprot - E9Q2R5
swissprot - E9Q352
Ensembl - ENSMUSG00000021557
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 agtpbp1ENSDARG00000105214Danio rerio
 AGTPBP1ENSGALG00000012595Gallus gallus
 Q9UPW5ENSG00000135049Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Agbl1 / Q09M05 / Cytosolic carboxypeptidase 4 / Q96MI9* / ATP/GTP binding protein like 1*ENSMUSG0000002575441
Agbl2 / Q8CDK2 / Mus musculus ATP/GTP binding protein-like 2 (Agbl2), transcript variant 2, mRNA. / Q5U5Z8* / ATP/GTP binding protein like 2*ENSMUSG0000004081220
Agbl3 / Q8CDP0 / Cytosolic carboxypeptidase 3 / Q8NEM8* / ATP/GTP binding protein like 3*ENSMUSG0000003883618
Agbl5 / Q09M02 / Cytosolic carboxypeptidase-like protein 5 / Q8NDL9* / ATP/GTP binding protein like 5*ENSMUSG0000002916513
Agbl4 / Q09LZ8 / Cytosolic carboxypeptidase 6 / Q5VU57* / ATP/GTP binding protein like 4*ENSMUSG0000006129812


Protein motifs (from Interpro)
Interpro ID Name
 IPR000834  Peptidase M14, carboxypeptidase A
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR033852  Cytosolic aminopeptidase 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001754 eye photoreceptor cell differentiation IMP
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007005 mitochondrion organization IMP
 biological_processGO:0007628 adult walking behavior IMP
 biological_processGO:0021549 cerebellum development IMP
 biological_processGO:0021680 cerebellar Purkinje cell layer development IMP
 biological_processGO:0021702 cerebellar Purkinje cell differentiation IEA
 biological_processGO:0021772 olfactory bulb development IMP
 biological_processGO:0035609 C-terminal protein deglutamylation IDA
 biological_processGO:0035610 protein side chain deglutamylation TAS
 biological_processGO:0042133 neurotransmitter metabolic process IMP
 biological_processGO:0050905 neuromuscular process IMP
 biological_processGO:0060041 retina development in camera-type eye IMP
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 molecular_functionGO:0004180 carboxypeptidase activity IEA
 molecular_functionGO:0004181 metallocarboxypeptidase activity TAS
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity TAS
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0015631 tubulin binding IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000745 tremors "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Agtpbp1m2Btlr/Agtpbp1m2Btlr
Genetic Background: C57BL/6J-Agtpbp1m2Btlr

 MP:0000819 abnormal olfactory bulb morphology "malformation or absence of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Principles of Neural Science:ISBN 0-8385-8034-3, J:16461]
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Allelic Composition: Pax6tm1Pgr/Pax6tm1Pgr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI

Allelic Composition: Agtpbp1pcd-Tg(Dhfr)1Jwg/Agtpbp1pcd-Tg(Dhfr)1Jwg
Genetic Background: involves: C57BL/6J * CD-1 * DBA/2J

Allelic Composition: Agtpbp1pcd-6J/Agtpbp1pcd-6J
Genetic Background: C57BL/6J-Agtpbp1pcd-6J/J

 MP:0000832 abnormal thalamus morphology "malformation or absence of the large ovoid mass of paired bodies containing mostly gray matter and forming part of the lateral wall of the third ventricle of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Pax6tm1Pgr/Pax6tm1Pgr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI

Allelic Composition: Agtpbp1pcd-3J/Agtpbp1pcd-3J
Genetic Background: involves: BALB/cByJ

 MP:0000852 small cerebellum "reduced size of cerebellum" [MGI:CLS, J:17203, J:67524]
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Allelic Composition: Agtpbp1pcd-5J/Agtpbp1pcd-5J
Genetic Background: DBA/2J

 MP:0000875 abnormal cerebellar Purkinje cell layer "any malformation or absence of the cell layer that lies just underneath the molecular layer of the cerebellar cortex; it contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer, and candelabrum interneurons are vertically oriented between the Purkinje cells" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Pax6tm1Pgr/Pax6tm1Pgr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI

 MP:0000876 Purkinje cell degeneration "a retrogressive impairment of function or destruction of the large neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex" [J:46854]
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Allelic Composition: Pax6tm1Pgr/Pax6tm1Pgr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI

Allelic Composition: Agtpbp1pcd-3J/Agtpbp1pcd-3J
Genetic Background: involves: BALB/cByJ

Allelic Composition: Agtpbp1pcd-Tg(Dhfr)1Jwg/Agtpbp1pcd-Tg(Dhfr)1Jwg
Genetic Background: involves: C57BL/6J * CD-1 * DBA/2J

Allelic Composition: Agtpbp1pcd-4J/Agtpbp1pcd-4J
Genetic Background: involves: C3H * C57BL/6J

Allelic Composition: Agtpbp1pcd-5J/Agtpbp1pcd-5J
Genetic Background: DBA/2J

Allelic Composition: Agtpbp1pcd-6J/Agtpbp1pcd-6J
Genetic Background: C57BL/6J-Agtpbp1pcd-6J/J

Allelic Composition: Agtpbp1pcd-7J/Agtpbp1pcd-7J
Genetic Background: C.Cg-Igh-6tm1Cgn Agtpbp1pcd-7J

Allelic Composition: Agtpbp1pcd-Btlr/Agtpbp1pcd-Btlr
Genetic Background: C57BL/6J-Agtpbp1pcd-Btlr

 MP:0000880 decreased Purkinje cell number "fewer than normal neuronal cells that are located in the interface of the molecular and granular layers of the cerebellar cortex" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:45302]
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Allelic Composition: Pax6tm1Pgr/Pax6tm1Pgr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI

Allelic Composition: Agtpbp1pcd-8J/Agtpbp1pcd-8J
Genetic Background: BALB/cJ-Agtpbp1pcd-8J/GrsrJ

Allelic Composition: Agtpbp1pcd/Agtpbp1pcd
Genetic Background: involves: C57BR/cdJ

 MP:0000886 abnormal cerebellar granule layer "any malformation or absence of the innermost cortical layer of the cerebellum; contains densly packed small neurons, mostly granule cells with some Golgi cells are found at the outer border" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Pax6tm1Pgr/Pax6tm1Pgr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI

Allelic Composition: Agtpbp1pcd-3J/Agtpbp1pcd-3J
Genetic Background: involves: BALB/cByJ

 MP:0001005 abnormal rod morphology "structural or developmental anomaly of the photoreceptors that contain rhodopsin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Apctm1Tno/Apc+,Il17ratm1Koll/Il17ratm1Koll,Tg(CDX2-cre)101Erf/0
Genetic Background: involves: 129 * 129S4/SvJae * C57BL/6J * SJL/J

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: H2-Ab1tm1Gru/H2-Ab1tm1Gru,Runx1tm1Toku/Runx1tm1Toku,Runx3tm1Itan/Runx3tm1Itan,Tg(Cd4-cre)1Cwi/0
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * DBA/2

Allelic Composition: Agtpbp1m2Btlr/Agtpbp1m2Btlr
Genetic Background: C57BL/6J-Agtpbp1m2Btlr

 MP:0001326 retinal degeneration "pathological change in the thin layer of neural tissue lining the back of the eyeball, which contains visual receptors and can result in the impairment or cessation of retinal neural function" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
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Allelic Composition: Agtpbp1pcd-5J/Agtpbp1pcd-5J
Genetic Background: DBA/2J

Allelic Composition: Agtpbp1pcd-6J/Agtpbp1pcd-6J
Genetic Background: C57BL/6J-Agtpbp1pcd-6J/J

Allelic Composition: Agtpbp1pcd-8J/Agtpbp1pcd-8J
Genetic Background: BALB/cJ-Agtpbp1pcd-8J/GrsrJ

 MP:0001393 ataxia "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]
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Allelic Composition: Pax6tm1Pgr/Pax6tm1Pgr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI

Allelic Composition: Agtpbp1pcd-3J/Agtpbp1pcd-3J
Genetic Background: involves: BALB/cByJ

Allelic Composition: Agtpbp1pcd-Tg(Dhfr)1Jwg/Agtpbp1pcd-Tg(Dhfr)1Jwg
Genetic Background: involves: C57BL/6J * CD-1 * DBA/2J

Allelic Composition: Agtpbp1pcd-4J/Agtpbp1pcd-4J
Genetic Background: involves: C3H * C57BL/6J

Allelic Composition: Agtpbp1pcd-5J/Agtpbp1pcd-5J
Genetic Background: DBA/2J

Allelic Composition: Agtpbp1pcd-6J/Agtpbp1pcd-6J
Genetic Background: C57BL/6J-Agtpbp1pcd-6J/J

Allelic Composition: Agtpbp1pcd-7J/Agtpbp1pcd-7J
Genetic Background: C.Cg-Igh-6tm1Cgn Agtpbp1pcd-7J

Allelic Composition: Agtpbp1pcd-8J/Agtpbp1pcd-8J
Genetic Background: BALB/cJ-Agtpbp1pcd-8J/GrsrJ

Allelic Composition: Agtpbp1pcd-Btlr/Agtpbp1pcd-Btlr
Genetic Background: C57BL/6J-Agtpbp1pcd-Btlr

Allelic Composition: Agtpbp1babe/Agtpbp1babe
Genetic Background: C57BL/6JSfdAnu-Agtpbp1babe/Anu

Allelic Composition: Agtpbp1pcd-2J/Agtpbp1pcd-2J
Genetic Background: SM/J

Allelic Composition: Agtpbp1pcd-9J/Agtpbp1pcd-9J,Batf2tm1Kmm/Batf2tm1Kmm
Genetic Background: involves: 129S1/SvImJ * 129S6/SvEvTac

 MP:0001516 abnormal motor coordination/ balance "altered ability of an animal to maintain skillful and effective interaction of movements or maintenance of equilibrium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ltbp4Gt(U3Cre)1Vmel/Ltbp4Gt(U3Cre)1Vmel
Genetic Background: involves: 129S2/SvPas

 MP:0001921 reduced fertility "diminished ability to produce live offspring" [J:65030]
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Allelic Composition: Agtpbp1pcd-6J/Agtpbp1pcd-6J
Genetic Background: C57BL/6J-Agtpbp1pcd-6J/J

 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
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Allelic Composition: Agtpbp1pcd-2J/Agtpbp1pcd-2J
Genetic Background: SM/J

 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Pax6tm1Pgr/Pax6tm1Pgr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI

Allelic Composition: Agtpbp1pcd-8J/Agtpbp1pcd-8J
Genetic Background: BALB/cJ-Agtpbp1pcd-8J/GrsrJ

 MP:0001924 infertility "inability to produce live offspring" [J:47225]
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Allelic Composition: Agtpbp1pcd-6J/Agtpbp1pcd-6J
Genetic Background: C57BL/6J-Agtpbp1pcd-6J/J

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Pax6tm1Pgr/Pax6tm1Pgr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI

Allelic Composition: Agtpbp1pcd-3J/Agtpbp1pcd-3J
Genetic Background: involves: BALB/cByJ

Allelic Composition: Agtpbp1pcd-Tg(Dhfr)1Jwg/Agtpbp1pcd-Tg(Dhfr)1Jwg
Genetic Background: involves: C57BL/6J * CD-1 * DBA/2J

Allelic Composition: Agtpbp1pcd-5J/Agtpbp1pcd-5J
Genetic Background: DBA/2J

Allelic Composition: Agtpbp1pcd-8J/Agtpbp1pcd-8J
Genetic Background: BALB/cJ-Agtpbp1pcd-8J/GrsrJ

Allelic Composition: Agtpbp1pcd-Btlr/Agtpbp1pcd-Btlr
Genetic Background: C57BL/6J-Agtpbp1pcd-Btlr

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Agtpbp1pcd-Tg(Dhfr)1Jwg/Agtpbp1pcd-Tg(Dhfr)1Jwg
Genetic Background: involves: C57BL/6J * CD-1 * DBA/2J

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Pax6tm1Pgr/Pax6tm1Pgr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI

Allelic Composition: Agtpbp1pcd-3J/Agtpbp1pcd-3J
Genetic Background: involves: BALB/cByJ

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
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Allelic Composition: Pax6tm1Pgr/Pax6tm1Pgr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI

Allelic Composition: Agtpbp1pcd-3J/Agtpbp1pcd-3J
Genetic Background: involves: BALB/cByJ

Allelic Composition: Agtpbp1pcd-Btlr/Agtpbp1pcd-Btlr
Genetic Background: C57BL/6J-Agtpbp1pcd-Btlr

 MP:0003205 testicular atrophy "wasting of the male reproductive glands resulting in reduced size" [RGD:Rat Genome Database submission]
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Allelic Composition: Agtpbp1pcd-6J/Agtpbp1pcd-6J
Genetic Background: C57BL/6J-Agtpbp1pcd-6J/J

 MP:0003727 abnormal retinal layer morphology "malformation in any of the layers that make up the retina" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Agtpbp1pcd-8J/Agtpbp1pcd-8J
Genetic Background: BALB/cJ-Agtpbp1pcd-8J/GrsrJ

 MP:0003728 abnormal photoreceptor layer "malformation/anomalous structure of the photoreceptor layer" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Agtpbp1pcd-5J/Agtpbp1pcd-5J
Genetic Background: DBA/2J

 MP:0003729 abnormal photoreceptor outer segments "malformation/anomalous structure of the photoreceptor layer which contains stacks of membranous discs that are rich in the visual pigment rhodopsin " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Agtpbp1pcd-5J/Agtpbp1pcd-5J
Genetic Background: DBA/2J

 MP:0003730 abnormal photoreceptor inner segments "malformation/anomalous structure of the photoreceptor layer which contains the machinery of the cell (mitochondria, golgi, endoplasmic reticulum, etc)" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Agtpbp1pcd-5J/Agtpbp1pcd-5J
Genetic Background: DBA/2J

 MP:0003731 abnormal outer nuclear layer morphology "malformation/anomalous structure of the retinal layer that contains the nuclei and cell bodies of rods and cones" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Apctm1Tno/Apc+,Il17ratm1Koll/Il17ratm1Koll,Tg(CDX2-cre)101Erf/0
Genetic Background: involves: 129 * 129S4/SvJae * C57BL/6J * SJL/J

 MP:0003734 abnormal inner plexiform layer morphology "malformation/anomalous structure of the retinal cell layer where bipolar and amacrine cell axons synapse with ganglion cell dendrites " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Apctm1Tno/Apc+,Il17ratm1Koll/Il17ratm1Koll,Tg(CDX2-cre)101Erf/0
Genetic Background: involves: 129 * 129S4/SvJae * C57BL/6J * SJL/J

 MP:0003993 abnormal ventral spinal root morphology "any anomaly, deformity, or malformation of the anterior bundle of nerves emerging from the spinal cord to join with the posterior/dorsal nerve bundle at each spinal cord segment to form one of the 31 paired peripheral nerves" [brs:Beverly Richards-Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Agtpbp1pcd-6J/Agtpbp1pcd-6J
Genetic Background: C57BL/6J-Agtpbp1pcd-6J/J

 MP:0004021 abnormal rod electrophysiology "anomaly in the function of dark adapted vision mediated by the rods" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Apctm1Tno/Apc+,Il17ratm1Koll/Il17ratm1Koll,Tg(CDX2-cre)101Erf/0
Genetic Background: involves: 129 * 129S4/SvJae * C57BL/6J * SJL/J

 MP:0004022 abnormal cone electrophysiology "anomaly in the function of light adapted vision mediated by the cones" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Apctm1Tno/Apc+,Il17ratm1Koll/Il17ratm1Koll,Tg(CDX2-cre)101Erf/0
Genetic Background: involves: 129 * 129S4/SvJae * C57BL/6J * SJL/J

 MP:0004738 abnormal brainstem auditory evoked potential "anomaly in the electrical activity generated in response to short tone bursts; may be used to evaluate sensorineural hearing function" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Agtpbp1pcd-7J/Agtpbp1pcd-7J
Genetic Background: C.Cg-Igh-6tm1Cgn Agtpbp1pcd-7J

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Agtpbp1pcd-Tg(Dhfr)1Jwg/Agtpbp1pcd-Tg(Dhfr)1Jwg
Genetic Background: involves: C57BL/6J * CD-1 * DBA/2J

Allelic Composition: Agtpbp1pcd-6J/Agtpbp1pcd-6J
Genetic Background: C57BL/6J-Agtpbp1pcd-6J/J

 MP:0005551 abnormal eye electrophysiology "abnormal function of the eye as determined through electrophysiological recordings from single cells or summary recordings from multiple cells (e.g. electroretinogram)" [NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
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Allelic Composition: Apctm1Tno/Apc+,Il17ratm1Koll/Il17ratm1Koll,Tg(CDX2-cre)101Erf/0
Genetic Background: involves: 129 * 129S4/SvJae * C57BL/6J * SJL/J

 MP:0005578 teratozoospermia "presence of malformed spermatozoa in the semen; malformations include the physical bending of the sperm to produce kinks or bends" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator]
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Allelic Composition: Agtpbp1pcd-Btlr/Agtpbp1pcd-Btlr
Genetic Background: C57BL/6J-Agtpbp1pcd-Btlr

 MP:0006362 abnormal male germ cell morphology "any structural anomaly of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Pax6tm1Pgr/Pax6tm1Pgr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI

Allelic Composition: Agtpbp1pcd-3J/Agtpbp1pcd-3J
Genetic Background: involves: BALB/cByJ

Allelic Composition: Agtpbp1pcd-8J/Agtpbp1pcd-8J
Genetic Background: BALB/cJ-Agtpbp1pcd-8J/GrsrJ

 MP:0008106 decreased amacrine cell number "reduction in the number of one of the three types of interneurons found in the inner nuclear layer of the mature retina" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Apctm1Tno/Apc+,Il17ratm1Koll/Il17ratm1Koll,Tg(CDX2-cre)101Erf/0
Genetic Background: involves: 129 * 129S4/SvJae * C57BL/6J * SJL/J

 MP:0008282 enlarged hippocampus "increased size of the deep lying structure of the cerebrum involved with memory storage and spatial navigation" [ISBN:0-12-402035-6 "Kaufman, MH The Atlas of Mouse Development", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Agtpbp1pcd-7J/Agtpbp1pcd-7J
Genetic Background: C.Cg-Igh-6tm1Cgn Agtpbp1pcd-7J

 MP:0008450 retinal photoreceptor degeneration "a retrogressive impairment of function or destruction of a cell specialized to detect and transduce light, including rods and cones of the retina" [MESH:A08.663.650.650, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pax6tm1Pgr/Pax6tm1Pgr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI

Allelic Composition: Agtpbp1pcd-3J/Agtpbp1pcd-3J
Genetic Background: involves: BALB/cByJ

Allelic Composition: Agtpbp1pcd-Tg(Dhfr)1Jwg/Agtpbp1pcd-Tg(Dhfr)1Jwg
Genetic Background: involves: C57BL/6J * CD-1 * DBA/2J

Allelic Composition: Agtpbp1pcd-Btlr/Agtpbp1pcd-Btlr
Genetic Background: C57BL/6J-Agtpbp1pcd-Btlr

Allelic Composition: Agtpbp1pcd/Agtpbp1pcd
Genetic Background: involves: C57BL/6J * C57BR/cdJ * DBA/2J

 MP:0008515 thin retinal outer nuclear layer "reduced thickness of the retinal layer that contains the nuclei and cell bodies of rods and cones" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Agtpbp1pcd-5J/Agtpbp1pcd-5J
Genetic Background: DBA/2J

Allelic Composition: Agtpbp1pcd/Agtpbp1pcd
Genetic Background: involves: C57BL/6J * C57BR/cdJ * DBA/2J

 MP:0008572 abnormal Purkinje cell dendrite morphology "any strucutral anomaly of the Purkinje cell body projections with hundreds of parallel spiny branches reaching up into the molecular layer" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pax6tm1Pgr/Pax6tm1Pgr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI

 MP:0009280 reduced activated sperm motility "loss or reduction of the activated type of sperm mobility, resulting in immotile sperm that are generally unable to reach the uterotubal junction; decreases in activated sperm motility may result in reduced male fertility" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Agtpbp1m2Btlr/Agtpbp1m2Btlr
Genetic Background: C57BL/6J-Agtpbp1m2Btlr

 MP:0009400 decreased skeletal muscle fiber size "decrease in the size of the large multinucleated cells that make up the skeletal muscles" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Agtpbp1pcd-6J/Agtpbp1pcd-6J
Genetic Background: C57BL/6J-Agtpbp1pcd-6J/J

 MP:0009434 paraparesis "a weakness affecting lower limbs" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Agtpbp1babe/Agtpbp1babe
Genetic Background: C57BL/6JSfdAnu-Agtpbp1babe/Anu

 MP:0009954 abnormal mitral cell morphology "any structural anomaly of the large glutaminergic nerve cells whose dendrites synapse with axons of the olfactory receptor neurons in the glomerular layer of the olfactory bulb, and whose axons pass centrally in the olfactory tract to the olfactory cortex" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Agtpbp1pcd-3J/Agtpbp1pcd-3J
Genetic Background: involves: BALB/cByJ

 MP:0012490 abnormal cochlear VIII nucleus morphology "any structural anomaly of two paired brainstem nuclei, the dorsal cochlear nucleus and the ventral cochlear nucleus, that lie dorsal and ventral, respectively, to the inferior cerebellar peduncle at the rostral pole of the medulla; the cochlear nuclei receive input from the cochlear nerve and send projections to the inferior colliculus, the medial geniculate, and other forebrain structures" [MGI:csmith]
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Allelic Composition: Agtpbp1pcd/Agtpbp1pcd
Genetic Background: involves: C57BR/cdJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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