ENSMUSG00000021578


Mus musculus

Features
Gene ID: ENSMUSG00000021578
  
Biological name :Ccdc127
  
Synonyms : Ccdc127 / Coiled-coil domain-containing protein 127 / Q3TC33
  
Possible biological names infered from orthology : coiled-coil domain containing 127 / Q96BQ5
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: C1
Gene start: 74350309
Gene end: 74365783
  
Corresponding Affymetrix probe sets: 10406193 (MoGene1.0st)   1436133_at (Mouse Genome 430 2.0 Array)   1439538_at (Mouse Genome 430 2.0 Array)   1449096_at (Mouse Genome 430 2.0 Array)   1455248_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000123805
Ensembl peptide - ENSMUSP00000125027
Ensembl peptide - ENSMUSP00000124193
Ensembl peptide - ENSMUSP00000124009
Ensembl peptide - ENSMUSP00000022063
NCBI entrez gene - 67433     See in Manteia.
MGI - MGI:1914683
RefSeq - NM_001168658
RefSeq - NM_001168659
RefSeq - NM_024201
RefSeq Peptide - NP_001162130
RefSeq Peptide - NP_077163
RefSeq Peptide - NP_001162129
swissprot - Q3TC33
swissprot - E0CYP1
swissprot - E0CXT2
swissprot - E0CYX9
Ensembl - ENSMUSG00000021578
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ccdc127bENSDARG00000008946Danio rerio
 zmp:0000000930ENSDARG00000104344Danio rerio
 CCDC127ENSGALG00000034628Gallus gallus
 Q96BQ5ENSG00000164366Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR034607  Coiled-coil domain-containing protein 127


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005014 increased B cell number "greater than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Catsper3tm1.1(KOMP)Vlcg/Catsper3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Catsper3tm1.1(KOMP)Vlcg/Ucd

 MP:0005015 increased T cell number "greater than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Catsper3tm1.1(KOMP)Vlcg/Catsper3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Catsper3tm1.1(KOMP)Vlcg/Ucd

 MP:0008045 decreased NK cell number "reduction in the number of non-T, non-B lymphocytes, having a granular morphology and which are important in innate immunity to viruses and other intracellular pathogens; in addition, these cells can kill certain tumor cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease"]
Show

Allelic Composition: Catsper3tm1.1(KOMP)Vlcg/Catsper3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Catsper3tm1.1(KOMP)Vlcg/Ucd

 MP:0008074 increased CD4-positive T cell number "greater number of the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Catsper3tm1.1(KOMP)Vlcg/Catsper3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Catsper3tm1.1(KOMP)Vlcg/Ucd

 MP:0008078 increased CD8-positive T cell number "greater number of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Catsper3tm1.1(KOMP)Vlcg/Catsper3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Catsper3tm1.1(KOMP)Vlcg/Ucd

 MP:0010168 increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number "a greater number of the CD4-positive, CD25-positive T cell subset which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release" [ISBN:0781735149]
Show

Allelic Composition: Catsper3tm1.1(KOMP)Vlcg/Catsper3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Catsper3tm1.1(KOMP)Vlcg/Ucd

 MP:0012764 increased alpha-beta T cell number "greater number of T cells that expresses an alpha-beta T cell receptor complex" [CL:0000789]
Show

Allelic Composition: Catsper3tm1.1(KOMP)Vlcg/Catsper3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Catsper3tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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