ENSMUSG00000021725


Mus musculus

Features
Gene ID: ENSMUSG00000021725
  
Biological name :Parp8
  
Synonyms : Parp8 / Poly [ADP-ribose] polymerase 8 / Q3UD82
  
Possible biological names infered from orthology : poly(ADP-ribose) polymerase family member 8 / Q8N3A8
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: D2.3
Gene start: 116854820
Gene end: 117025537
  
Corresponding Affymetrix probe sets: 10412345 (MoGene1.0st)   1451474_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000153307
Ensembl peptide - ENSMUSP00000152911
Ensembl peptide - ENSMUSP00000153169
Ensembl peptide - ENSMUSP00000153188
Ensembl peptide - ENSMUSP00000022239
NCBI entrez gene - 52552     See in Manteia.
MGI - MGI:1098713
RefSeq - XM_011244679
RefSeq - NM_001081009
RefSeq - XM_006517718
RefSeq - XM_006517719
RefSeq - XM_006517720
RefSeq Peptide - NP_001074478
swissprot - Q3UD82
swissprot - A0A286YDC6
swissprot - F8WIK2
swissprot - A0A286YD73
swissprot - A0A286YCW0
Ensembl - ENSMUSG00000021725
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 parp8ENSDARG00000059789Danio rerio
 ENSGALG00000032991Gallus gallus
 PARP8ENSG00000151883Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Parp6 / poly(ADP-ribose) polymerase family member 6 / Q2NL67*ENSMUSG0000002523744


Protein motifs (from Interpro)
Interpro ID Name
 IPR012317  Poly(ADP-ribose) polymerase, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005622 intracellular ISO
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003950 NAD+ ADP-ribosyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA


Pathways (from Reactome)
Pathway description
Nicotinamide salvaging


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Nampttm1.1(KOMP)Vlcg/Nampttm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Nampttm1.1(KOMP)Vlcg/Ucd

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
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Allelic Composition: Nampttm1.1(KOMP)Vlcg/Nampttm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Nampttm1.1(KOMP)Vlcg/Ucd

 MP:0003064 decreased coping response "reduced ability to respond productively to a stressful situation" [RGD:Rat Genome Database submission]
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Allelic Composition: Nampttm1.1(KOMP)Vlcg/Nampttm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Nampttm1.1(KOMP)Vlcg/Ucd

 MP:0011275 abnormal behavioral response to light "unexpected change in the activity of an organism (in terms of movement, outward responses) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light" [GO:0009416, MGI:llw2]
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Allelic Composition: Nampttm1.1(KOMP)Vlcg/Nampttm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Nampttm1.1(KOMP)Vlcg/Ucd

 MP:0011396 abnormal sleep behavior "any anomaly in the actions, reactions, or performance of an organism during a periodic, readily reversible state of reduced awareness and metabolic activity" [MGI:smb]
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Allelic Composition: Nampttm1.1(KOMP)Vlcg/Nampttm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Nampttm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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