ENSMUSG00000021900


Mus musculus

Features
Gene ID: ENSMUSG00000021900
  
Biological name :Btd
  
Synonyms : biotinidase / Btd
  
Possible biological names infered from orthology : P43251
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: B
Gene start: 31641028
Gene end: 31668579
  
Corresponding Affymetrix probe sets: 10413803 (MoGene1.0st)   1417987_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000087608
NCBI entrez gene - 26363     See in Manteia.
MGI - MGI:1347001
RefSeq - NM_025295
RefSeq - XM_006519029
RefSeq Peptide - NP_079571
swissprot - A0A0R4J131
Ensembl - ENSMUSG00000021900
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 btdENSDARG00000099596Danio rerio
 BTDENSGALG00000011216Gallus gallus
 BTDENSG00000169814Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Vnn1 / Q9Z0K8 / vanin 1 / O95497*ENSMUSG0000003744040
Vnn3 / Q9QZ25 / vanin 3 / Q9NY84*ENSMUSG0000002001037


Protein motifs (from Interpro)
Interpro ID Name
 IPR003010  Carbon-nitrogen hydrolase
 IPR012101  Biotinidase-like, eukaryotic
 IPR036526  Carbon-nitrogen hydrolase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006807 nitrogen compound metabolic process IEA
 molecular_functionGO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides IEA


Pathways (from Reactome)
Pathway description
Biotin transport and metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000414 alopecia "absence of hair or loss of hair; not usually in reference to primary genetic hairlessness but may be due to dietary, stress, secondary to immune condition" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:30772, J:33796]
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Allelic Composition: Fasltm1.1Cgm/Fasltm1.1Cgm
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N

 MP:0000745 tremors "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Fasltm1.1Cgm/Fasltm1.1Cgm
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N

 MP:0000746 weakness "state of being infirm or less strong than littermates" [J:45400]
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Allelic Composition: Fasltm1.1Cgm/Fasltm1.1Cgm
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N

 MP:0000755 hindlimb paralysis "loss of power of voluntary movement in the muscles of the hindlimb through injury or disease of it or its nerve supply" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Fasltm1.1Cgm/Fasltm1.1Cgm
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N

 MP:0000756 forelimb paralysis "loss of power of voluntary movement in muscles of the forlimb through injury or disease of it or its nerve supply" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Fasltm1.1Cgm/Fasltm1.1Cgm
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N

 MP:0001263 weight loss "progressive reduction of body weight below normal average for age" [J:45400]
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Allelic Composition: Fasltm1.1Cgm/Fasltm1.1Cgm
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
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Allelic Composition: Fasltm1.1Cgm/Fasltm1.1Cgm
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N

 MP:0001505 hunched posture "stooped low with the limbs pulled in close to the body and arched back" [J:67231, J:30404]
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Allelic Composition: Fasltm1.1Cgm/Fasltm1.1Cgm
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N

 MP:0002075 abnormal coat color "irregular or unusual pigmentation pattern of the hair in relation to control animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Fasltm1.1Cgm/Fasltm1.1Cgm
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N

 MP:0004016 decreased bone mass "a reduction in the total amount of bone tissue contained in the skeleton" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Fasltm1.1Cgm/Fasltm1.1Cgm
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N

 MP:0004144 hypotonia "decreased muscle tension resulting in limpness of the muscles in the resting state, not to be confused with weakness" [hdene:Howard Dene , Mouse Genome Informatics Curator]
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Allelic Composition: Fasltm1.1Cgm/Fasltm1.1Cgm
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fasltm1.1Cgm/Fasltm1.1Cgm
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N

 MP:0005202 lethargy "mild impairment of consciousness resulting in reduced alertness and awareness; ultimately due to generalized brain dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Fasltm1.1Cgm/Fasltm1.1Cgm
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N

 MP:0005253 abnormal eye physiology "anomalous function and/or activity of the ocular system or any of its parts" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Fasltm1.1Cgm/Fasltm1.1Cgm
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N

 MP:0005309 increased circulating ammonia level "significantly elevated levels of ammonia or its compounds in blood; often associated with liver failure and hepatic encephalopathy " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83263]
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Allelic Composition: Fasltm1.1Cgm/Fasltm1.1Cgm
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N

 MP:0009643 abnormal urine homeostasis "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions and chemical or protein composition of the urine" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fasltm1.1Cgm/Fasltm1.1Cgm
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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