ENSMUSG00000022012


Mus musculus

Features
Gene ID: ENSMUSG00000022012
  
Biological name :Enox1
  
Synonyms : Ecto-NOX disulfide-thiol exchanger 1 Hydroquinone [NADH] oxidase Protein disulfide-thiol oxidoreductase / Enox1 / Q8BHR2
  
Possible biological names infered from orthology : ecto-NOX disulfide-thiol exchanger 1 / Q8TC92
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: D3
Gene start: 77156763
Gene end: 77721760
  
Corresponding Affymetrix probe sets: 10416541 (MoGene1.0st)   1436799_at (Mouse Genome 430 2.0 Array)   1447857_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022589
Ensembl peptide - ENSMUSP00000154296
Ensembl peptide - ENSMUSP00000154512
NCBI entrez gene - 239188     See in Manteia.
MGI - MGI:2444896
RefSeq - XM_017316018
RefSeq - NM_001253759
RefSeq - NM_172813
RefSeq - XM_011245065
RefSeq - XM_011245066
RefSeq - XM_011245067
RefSeq - XM_006518999
RefSeq - XM_006519000
RefSeq - XM_006519001
RefSeq - XM_006519005
RefSeq - XM_006519006
RefSeq - XM_011245063
RefSeq - XM_011245064
RefSeq Peptide - NP_766401
RefSeq Peptide - NP_001240688
swissprot - Q8BHR2
Ensembl - ENSMUSG00000022012
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 enox1ENSDARG00000060243Danio rerio
 ENOX1ENSGALG00000016967Gallus gallus
 ENOX1ENSG00000120658Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Enox2 / Q8R0Z2 / Ecto-NOX disulfide-thiol exchanger 2 Hydroquinone [NADH] oxidase Protein disulfide-thiol oxidoreductase / Q16206* / ecto-NOX disulfide-thiol exchanger 2*ENSMUSG0000003110961


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR034140  Ecto-NOX disulfide-thiol exchanger, RNA recognition motif
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000062 increased bone density "increased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295]
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Allelic Composition: Egr1tm1b(NCOM)Mfgc/Egr1tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Egr1tm1b(NCOM)Mfgc/Tcp

 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
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Allelic Composition: Egr1tm1b(NCOM)Mfgc/Egr1tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Egr1tm1b(NCOM)Mfgc/Tcp

 MP:0010024 increased total body fat amount "greater than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Egr1tm1b(NCOM)Mfgc/Egr1tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Egr1tm1b(NCOM)Mfgc/Tcp

 MP:0011968 decreased threshold for auditory brainstem response "reduction in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system" [MGI:csmith]
Show

Allelic Composition: Egr1tm1b(NCOM)Mfgc/Egr1tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Egr1tm1b(NCOM)Mfgc/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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