ENSMUSG00000022013


Mus musculus

Features
Gene ID: ENSMUSG00000022013
  
Biological name :Dnajc15
  
Synonyms : Dnajc15 / DnaJ homolog subfamily C member 15 / Q78YY6
  
Possible biological names infered from orthology : DnaJ heat shock protein family (Hsp40) member C15 / Q9Y5T4
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: D3
Gene start: 77820681
Gene end: 77875125
  
Corresponding Affymetrix probe sets: 10421723 (MoGene1.0st)   1416910_at (Mouse Genome 430 2.0 Array)   1430378_at (Mouse Genome 430 2.0 Array)   1453306_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022590
Ensembl peptide - ENSMUSP00000154390
NCBI entrez gene - 66148     See in Manteia.
MGI - MGI:1913398
RefSeq - NM_025384
RefSeq Peptide - NP_079660
swissprot - Q78YY6
Ensembl - ENSMUSG00000022013
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnajc15ENSDARG00000038309Danio rerio
 DNAJC15ENSGALG00000016965Gallus gallus
 Q9Y5T4ENSG00000120675Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9CQV7 / Dnajc19 / Mitochondrial import inner membrane translocase subunit TIM14 ENSMUSG0000002767934


Protein motifs (from Interpro)
Interpro ID Name
 IPR001623  DnaJ domain
 IPR036869  Chaperone J-domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009267 cellular response to starvation IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0019216 regulation of lipid metabolic process IMP
 biological_processGO:0031333 negative regulation of protein complex assembly IMP
 biological_processGO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone IMP
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005743 mitochondrial inner membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000689 abnormal spleen morphology "atypical structure of the organ that functions to filter blood and to store red corpuscles and platelets" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:27463]
Show

Allelic Composition: Diaph3tm1b(KOMP)Mbp/Diaph3tm1b(KOMP)Mbp
Genetic Background: C57BL/6N-Diaph3tm1b(KOMP)Mbp/J

 MP:0001783 decreased white fat amount "reduced quantity of fat-storing cells/tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Atg5tm1Myok/Atg5tm1Myok,Tg(CAG-EGFP/Map1lc3b)53Nmz/0,Tg(Cryaa-cre)10Mlr/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * DBA/2 * FVB/N

 MP:0002118 abnormal lipid homeostasis "anomaly in the state of equilibrium in the body with respect to lipids in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Atg5tm1Myok/Atg5tm1Myok,Tg(CAG-EGFP/Map1lc3b)53Nmz/0,Tg(Cryaa-cre)10Mlr/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * DBA/2 * FVB/N

 MP:0002310 resistance to fatty liver development "less likely than the norm to to develop hepatic steatosis " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Atg5tm1Myok/Atg5tm1Myok,Tg(CAG-EGFP/Map1lc3b)53Nmz/0,Tg(Cryaa-cre)10Mlr/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * DBA/2 * FVB/N

 MP:0002644 decreased circulating triglyceride level "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Atg5tm1Myok/Atg5tm1Myok,Tg(CAG-EGFP/Map1lc3b)53Nmz/0,Tg(Cryaa-cre)10Mlr/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * DBA/2 * FVB/N

 MP:0002702 decreased circulating free fatty acid level "lower than normal levels of unesterified fatty acids in the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Atg5tm1Myok/Atg5tm1Myok,Tg(CAG-EGFP/Map1lc3b)53Nmz/0,Tg(Cryaa-cre)10Mlr/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * DBA/2 * FVB/N

 MP:0002981 increased liver weight "a greater than average weight of the bile-secreting exocrine gland" [il:Ira Lu , Mouse Genome Informatics Curator]
Show

Allelic Composition: Atg5tm1Myok/Atg5tm1Myok,Tg(CAG-EGFP/Map1lc3b)53Nmz/0,Tg(Cryaa-cre)10Mlr/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * DBA/2 * FVB/N

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Diaph3tm1b(KOMP)Mbp/Diaph3tm1b(KOMP)Mbp
Genetic Background: C57BL/6N-Diaph3tm1b(KOMP)Mbp/J

 MP:0005010 abnormal CD8+ T cell morphology/development "anomalous structure, formation, or numbers of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Atg5tm1Myok/Atg5tm1Myok,Tg(CAG-EGFP/Map1lc3b)53Nmz/0,Tg(Cryaa-cre)10Mlr/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * DBA/2 * FVB/N

 MP:0005438 abnormal glycogen homeostasis "abnormal processing and or utilization of this readily converted carbohydrate reserve, found in most tissues of the body, especially liver and muscle" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Atg5tm1Myok/Atg5tm1Myok,Tg(CAG-EGFP/Map1lc3b)53Nmz/0,Tg(Cryaa-cre)10Mlr/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * DBA/2 * FVB/N

 MP:0005440 increased glycogen level "greater than the normal concentration of this readily converted carbohydrate reserve, found in most tissues of the body, especially liver and muscle" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Atg5tm1Myok/Atg5tm1Myok,Tg(CAG-EGFP/Map1lc3b)53Nmz/0,Tg(Cryaa-cre)10Mlr/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * DBA/2 * FVB/N

 MP:0010026 decreased liver cholesterol level "less than normal amount in the liver of the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones; it is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Atg5tm1Myok/Atg5tm1Myok,Tg(CAG-EGFP/Map1lc3b)53Nmz/0,Tg(Cryaa-cre)10Mlr/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * DBA/2 * FVB/N

 MP:0010400 increased liver glycogen level "greater than the normal concentration of a readily converted carbohydrate reserve in liver" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Atg5tm1Myok/Atg5tm1Myok,Tg(CAG-EGFP/Map1lc3b)53Nmz/0,Tg(Cryaa-cre)10Mlr/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * DBA/2 * FVB/N

 MP:0010956 abnormal mitochondrial ATP synthesis coupled electron transport "anomaly in the transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane and mediated by multisubunit enzyme complexes known as complex I-IV" [GO:0042775, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Atg5tm1Myok/Atg5tm1Myok,Tg(CAG-EGFP/Map1lc3b)53Nmz/0,Tg(Cryaa-cre)10Mlr/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * DBA/2 * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr