ENSMUSG00000022016


Mus musculus

Features
Gene ID: ENSMUSG00000022016
  
Biological name :Akap11
  
Synonyms : Akap11 / A kinase (PRKA) anchor protein 11
  
Possible biological names infered from orthology : A-kinase anchoring protein 11 / Q9UKA4
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: D3
Gene start: 78492246
Gene end: 78536808
  
Corresponding Affymetrix probe sets: 10421749 (MoGene1.0st)   10421758 (MoGene1.0st)   10421768 (MoGene1.0st)   1434764_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000116015
Ensembl peptide - ENSMUSP00000022593
NCBI entrez gene - 219181     See in Manteia.
MGI - MGI:2684060
RefSeq - XM_017315981
RefSeq - XM_006518898
RefSeq - XM_006518899
RefSeq - XM_006518901
RefSeq - XM_006518902
RefSeq - NM_001164503
RefSeq - NM_001346784
RefSeq Peptide - NP_001333713
RefSeq Peptide - NP_001157975
swissprot - E9Q777
swissprot - E9Q774
Ensembl - ENSMUSG00000022016
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 akap11ENSDARG00000075435Danio rerio
 AKAP11ENSGALG00000022739Gallus gallus
 AKAP11ENSG00000023516Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sphkap / SPHK1 interactor, AKAP domain containing / Q2M3C7*ENSMUSG0000002616315


Protein motifs (from Interpro)
Interpro ID Name
 IPR008382  SPHK1-interactor/A-kinase anchor 110kDa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010738 regulation of protein kinase A signaling IBA
 biological_processGO:0042325 regulation of phosphorylation IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005777 peroxisome ISO
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0019207 kinase regulator activity ISO
 molecular_functionGO:0051018 protein kinase A binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000221 decreased WBC count "fewer than normal numbers of WBCs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: A830005F24Riktm1.1(KOMP)Mbp/A830005F24Rik+
Genetic Background: C57BL/6N-A830005F24Riktm1.1(KOMP)Mbp/Ucd

 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Cd19tm1(cre)Cgn/Cd19+,Ell2tm2.1Cmil/Ell2tm2.1Cmil
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Cd19tm1(cre)Cgn/Cd19+,Ell2tm2.1Cmil/Ell2tm2.1Cmil
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Cd19tm1(cre)Cgn/Cd19+,Ell2tm2.1Cmil/Ell2tm2.1Cmil
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

 MP:0001363 increased anxiety-related response "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060]
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Allelic Composition: Cd19tm1(cre)Cgn/Cd19+,Ell2tm2.1Cmil/Ell2tm2.1Cmil
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
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Allelic Composition: Cd19tm1(cre)Cgn/Cd19+,Ell2tm2.1Cmil/Ell2tm2.1Cmil
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

 MP:0002764 short tibia " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Cd19tm1(cre)Cgn/Cd19+,Ell2tm2.1Cmil/Ell2tm2.1Cmil
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

 MP:0002797 thigmotaxis "preference of a mouse for the side walls of a cage or box; usually an indicator of increased anxiety response" [J:56814]
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Allelic Composition: Cd19tm1(cre)Cgn/Cd19+,Ell2tm2.1Cmil/Ell2tm2.1Cmil
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

 MP:0004754 abnormal kidney collecting duct "any structural anomaly of the duct that drains fluid from the nephron and either allows bodily reabsorbtion of water or allows the fluid to drain to the bladder via the ureter; the collecting duct system also maintains acid-base homeostasis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cd19tm1(cre)Cgn/Cd19+,Ell2tm2.1Cmil/Ell2tm2.1Cmil
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

 MP:0008055 increased urine osmolality "increase in the concentration of ions in the urine compared to the normal state" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cd19tm1(cre)Cgn/Cd19+,Ell2tm2.1Cmil/Ell2tm2.1Cmil
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

 MP:0020211 slow movement "decreased rate or speed of the coordinated movements executed with a purpose" [GOC:NV]
Show

Allelic Composition: Cd19tm1(cre)Cgn/Cd19+,Ell2tm2.1Cmil/Ell2tm2.1Cmil
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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