ENSMUSG00000022089


Mus musculus

Features
Gene ID: ENSMUSG00000022089
  
Biological name :Bin3
  
Synonyms : Bin3 / Bridging integrator 3 / Q9JI08
  
Possible biological names infered from orthology : Q9NQY0
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: D2
Gene start: 70100105
Gene end: 70138206
  
Corresponding Affymetrix probe sets: 10416256 (MoGene1.0st)   1417691_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022680
Ensembl peptide - ENSMUSP00000154413
NCBI entrez gene - 57784     See in Manteia.
MGI - MGI:1929883
RefSeq - XM_011245124
RefSeq - NM_021328
RefSeq - XM_006519331
RefSeq - XM_006519332
RefSeq - XM_006519330
RefSeq Peptide - NP_067303
swissprot - Q9JI08
Ensembl - ENSMUSG00000022089
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bin3ENSDARG00000099651Danio rerio
 BIN3ENSG00000147439Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004148  BAR domain
 IPR027267  AH/BAR domain superfamily
 IPR037428  Bridging integrator 3, BAR domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000917 division septum assembly IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0008104 protein localization IEA
 biological_processGO:0009826 unidimensional cell growth IEA
 biological_processGO:0010591 regulation of lamellipodium assembly IMP
 biological_processGO:0014839 myoblast migration involved in skeletal muscle regeneration IMP
 biological_processGO:0043403 skeletal muscle tissue regeneration IMP
 biological_processGO:0048741 skeletal muscle fiber development IMP
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005884 actin filament IDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000240 extramedullary hematopoiesis "formation and development of blood cells outside the bone marrow, e.g., in the spleen, liver, or lymph nodes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Fshrtm1Saco/Fshr+
Genetic Background: involves: 129/Sv

 MP:0000607 abnormal hepatocyte morphology "malformation of the main structural component of the liver; these are specialized epithelial cells normally organize into interconnected plates called lobules" [J:23170, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Fshrtm1Saco/Fshr+
Genetic Background: involves: 129/Sv

 MP:0000691 enlarged spleen "increased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Fshrtm1Saco/Fshr+
Genetic Background: involves: 129/Sv

 MP:0001304 cataracts "complete or partial opacity of the lens" [J:65031]
Show

Allelic Composition: Fshrtm1Saco/Fshr+
Genetic Background: involves: 129/Sv

 MP:0001577 anemia "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
Show

Allelic Composition: Fshrtm1Saco/Fshr+
Genetic Background: involves: 129/Sv

 MP:0001860 liver inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the liver" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Fshrtm1Saco/Fshr+
Genetic Background: involves: 129/Sv

 MP:0001861 lung inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the lung" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Fshrtm1Saco/Fshr+
Genetic Background: involves: 129/Sv

 MP:0002027 lung adenocarcinoma "malignant neoplasm of epithelial cells in the lung" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:18542]
Show

Allelic Composition: Fshrtm1Saco/Fshr+
Genetic Background: involves: 129/Sv

 MP:0002840 abnormal lens fibers morphology "structural anomaly of the elongated cells of the crystalline lens of the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Fshrtm1Saco/Fshr+
Genetic Background: involves: 129/Sv

 MP:0004500 increased incidence of ionizing radiation-induced tumors "higher than normal frequency of tumor incidence induced by radiation in which the individual particle or photon carries sufficient energy to completely remove an electron from its orbit; common types of this radiation include gamma-rays and X-rays" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fshrtm1Saco/Fshr+
Genetic Background: involves: 129/Sv

 MP:0012431 increased lymphoma incidence "greater than the expected number of neoplasms characterized by a proliferation of malignant lymphocytes in lymphoid tissue in a specific population in a given time period" [http://orcid.org/0000-0001-5208-3432, MGI:csmith]
Show

Allelic Composition: Fshrtm1Saco/Fshr+
Genetic Background: involves: 129/Sv

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr