ENSMUSG00000022125


Mus musculus

Features
Gene ID: ENSMUSG00000022125
  
Biological name :Cln5
  
Synonyms : Ceroid-lipofuscinosis neuronal Ceroid-lipofuscinosis neuronal , secreted form / Cln5 / Q3UMW8
  
Possible biological names infered from orthology : AC001226.2 / CLN5, intracellular trafficking protein / O75503
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: E2.3
Gene start: 103070216
Gene end: 103077628
  
Corresponding Affymetrix probe sets: 10416843 (MoGene1.0st)   1426886_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000154528
Ensembl peptide - ENSMUSP00000022721
NCBI entrez gene - 211286     See in Manteia.
MGI - MGI:2442253
RefSeq - NM_001033242
RefSeq Peptide - NP_001028414
swissprot - B2RUP8
swissprot - Q3UMW8
Ensembl - ENSMUSG00000022125
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cln5ENSDARG00000076339Danio rerio
 CLN5ENSGALG00000016917Gallus gallus
 AC001226.2ENSG00000283208Homo sapiens
 CLN5ENSG00000102805Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026138  Ceroid-lipofuscinosis neuronal protein 5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006465 signal peptide processing ISO
 biological_processGO:0007040 lysosome organization IMP
 biological_processGO:0007042 lysosomal lumen acidification ISS
 biological_processGO:0007420 brain development ISS
 biological_processGO:0007601 visual perception IMP
 biological_processGO:0022008 neurogenesis ISS
 biological_processGO:0042147 retrograde transport, endosome to Golgi ISO
 biological_processGO:0070085 glycosylation ISO
 biological_processGO:1904426 positive regulation of GTP binding ISO
 cellular_componentGO:0005764 lysosome ISO
 cellular_componentGO:0005765 lysosomal membrane ISO
 cellular_componentGO:0005775 vacuolar lumen IDA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005537 mannose binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002090 abnormal vision "inability or decreased ability to see " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Agtpbp1pcd-6J/Agtpbp1pcd-6J
Genetic Background: C57BL/6J-Agtpbp1pcd-6J/J

 MP:0002152 abnormal brain morphology "anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk]
Show

Allelic Composition: Agtpbp1pcd-6J/Agtpbp1pcd-6J
Genetic Background: C57BL/6J-Agtpbp1pcd-6J/J

 MP:0003246 loss of GABA neurons "loss of the neurons that utilize gamma-aminobutyric acid as a neurotransmitter, commonly due to an apoptotic event" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Agtpbp1pcd-6J/Agtpbp1pcd-6J
Genetic Background: C57BL/6J-Agtpbp1pcd-6J/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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