| MP:0000780 | abnormal corpus callosum morphology | "malformation or absence of a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres; it consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ntrk2tm2Lfr/Ntrk2tm2Lfr,Tg(Six3-cre)69Frty/?,Tg(Thy1-YFP)HJrs/?
Genetic Background: involves: C57BL/6 * CBA * DBA/2
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| MP:0000783 | abnormal forebrain morphology | "malformed or absent anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857] |
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Allelic Composition: Ntrk2tm2Lfr/Ntrk2tm2Lfr,Tg(Six3-cre)69Frty/?,Tg(Thy1-YFP)HJrs/?
Genetic Background: involves: C57BL/6 * CBA * DBA/2
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| MP:0000841 | abnormal hindbrain morphology | "malformed caudal region of the brain; includes cerebellum, pons and medulla oblongata" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302] |
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Allelic Composition: Ntrk2tm2Lfr/Ntrk2tm2Lfr,Tg(Six3-cre)69Frty/?,Tg(Thy1-YFP)HJrs/?
Genetic Background: involves: C57BL/6 * CBA * DBA/2
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| MP:0000849 | abnormal cerebellum morphology | "any malformation or absence of the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement and learning of motor skills" [J:50311, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Ntrk2tm2Lfr/Ntrk2tm2Lfr,Tg(Six3-cre)69Frty/?,Tg(Thy1-YFP)HJrs/?
Genetic Background: involves: C57BL/6 * CBA * DBA/2
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| MP:0001454 | abnormal cued conditioning behavior | "defect in the ability of an animal to learn and remember an association between an an aversive experience (the unconditioned stimulus (US), ususally a shock) and a neutral stimulus (the conditioned stimulus (CS), usually an auditory cue or light)" [CFG:Center for Functional Genomics , Northwestern University] |
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Allelic Composition: Ntrk2tm2Lfr/Ntrk2tm2Lfr,Tg(Six3-cre)69Frty/?,Tg(Thy1-YFP)HJrs/?
Genetic Background: involves: C57BL/6 * CBA * DBA/2
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| MP:0001516 | abnormal motor coordination/ balance | "altered ability of an animal to maintain skillful and effective interaction of movements or maintenance of equilibrium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ntrk2tm2Lfr/Ntrk2tm2Lfr,Tg(Six3-cre)69Frty/?,Tg(Thy1-YFP)HJrs/?
Genetic Background: involves: C57BL/6 * CBA * DBA/2
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| MP:0002920 | reduced paired-pulse facilitation | "decrease in the response of central synapses when activated twice in rapid succession; indicative of defects in short-term plasticity due to lack of increase of neurotransmitter release at the second stimulus" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Ntrk2tm2Lfr/Ntrk2tm2Lfr,Tg(Six3-cre)69Frty/?,Tg(Thy1-YFP)HJrs/?
Genetic Background: involves: C57BL/6 * CBA * DBA/2
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| MP:0003224 | neuron degeneration | "a retrogressive impairment of function or destruction of the functional cells of the nervous system that receive, conduct, and transmit impulses " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ntrk2tm2Lfr/Ntrk2tm2Lfr,Tg(Six3-cre)69Frty/?,Tg(Thy1-YFP)HJrs/?
Genetic Background: involves: C57BL/6 * CBA * DBA/2
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| MP:0003633 | abnormal nervous system physiology | |
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Allelic Composition: Ntrk2tm2Lfr/Ntrk2tm2Lfr,Tg(Six3-cre)69Frty/?,Tg(Thy1-YFP)HJrs/?
Genetic Background: involves: C57BL/6 * CBA * DBA/2
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| MP:0004077 | abnormal striatum morphology | "malformation of a large cluster of dopaminergic nerve cells, consisting of the caudate nucleus and the putamen, that controls movement, balance, and walking" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Ntrk2tm2Lfr/Ntrk2tm2Lfr,Tg(Six3-cre)69Frty/?,Tg(Thy1-YFP)HJrs/?
Genetic Background: involves: C57BL/6 * CBA * DBA/2
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| MP:0004102 | abnormal dorsal striatum morphology | "any structural abnormality of the regions of the caudate nucleus and the putamen that lie dorsal to the anterior commissure" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ntrk2tm2Lfr/Ntrk2tm2Lfr,Tg(Six3-cre)69Frty/?,Tg(Thy1-YFP)HJrs/?
Genetic Background: involves: C57BL/6 * CBA * DBA/2
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| MP:0005405 | axon degeneration | "retrogressive pathologic change in the single process of a nerve cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ntrk2tm2Lfr/Ntrk2tm2Lfr,Tg(Six3-cre)69Frty/?,Tg(Thy1-YFP)HJrs/?
Genetic Background: involves: C57BL/6 * CBA * DBA/2
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| MP:0008025 | brain vacuoles | "the abnormal presence of cavities or fluid-filled vesicles in the soma of brain cells, often indicative of spongiosis or other pathological states" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ntrk2tm2Lfr/Ntrk2tm2Lfr,Tg(Six3-cre)69Frty/?,Tg(Thy1-YFP)HJrs/?
Genetic Background: involves: C57BL/6 * CBA * DBA/2
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| MP:0008235 | increased susceptibility to neuronal excitotoxicity | "greater than normal amount of neuronal cell death following exposure to a neurotoxic compound, such as kaniate-induced neuronal cell death mediated via a glutamate excitotoxic process" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ntrk2tm2Lfr/Ntrk2tm2Lfr,Tg(Six3-cre)69Frty/?,Tg(Thy1-YFP)HJrs/?
Genetic Background: involves: C57BL/6 * CBA * DBA/2
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| MP:0008873 | increased sensitivity to xenobiotics | "decrease in the dose or concentration of a foreign compound required to induce a specific level of response" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ntrk2tm2Lfr/Ntrk2tm2Lfr,Tg(Six3-cre)69Frty/?,Tg(Thy1-YFP)HJrs/?
Genetic Background: involves: C57BL/6 * CBA * DBA/2
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