ENSMUSG00000022598


Mus musculus

Features
Gene ID: ENSMUSG00000022598
  
Biological name :Psca
  
Synonyms : P57096 / Prostate stem cell antigen / Psca
  
Possible biological names infered from orthology : O43653
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: D3
Gene start: 74714839
Gene end: 74717069
  
Corresponding Affymetrix probe sets: 10424662 (MoGene1.0st)   1451258_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000023265
NCBI entrez gene - 72373     See in Manteia.
MGI - MGI:1919623
RefSeq - NM_028216
RefSeq Peptide - NP_082492
swissprot - P57096
Ensembl - ENSMUSG00000022598
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PSCAENSGALG00000045875Gallus gallus
 PSCAENSG00000167653Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR016054  Ly-6 antigen/uPA receptor-like
 IPR018363  CD59 antigen, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0099601 regulation of neurotransmitter receptor activity IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0031225 anchored component of membrane IEA
 molecular_functionGO:0033130 acetylcholine receptor binding IEA


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000689 abnormal spleen morphology "atypical structure of the organ that functions to filter blood and to store red corpuscles and platelets" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:27463]
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Allelic Composition: Ppp3r2tm1.1(KOMP)Vlcg/Ppp3r2tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Ppp3r2tm1.1(KOMP)Vlcg/Ucd

 MP:0001415 increased exploration in new environment "greater amount of time spent investigating new location" [J:28825]
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Allelic Composition: Ppp3r2tm1.1(KOMP)Vlcg/Ppp3r2tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Ppp3r2tm1.1(KOMP)Vlcg/Ucd

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tyrp1b-cH/Tyrp1b
Genetic Background: involves: 101/H * C3H/HeH * T Stock

 MP:0009219 prostate intraepithelial neoplasia "noninvasive prostate duct lesions that affect smaller caliber ducts" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tyrp1b-cH/Tyrp1b
Genetic Background: involves: 101/H * C3H/HeH * T Stock

Allelic Composition: Pscatm1Witt/Psca+,Tg(TRAMP)8247Ng/0
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0009220 prostate adenocarcinoma "malignant neoplasm arising from prostate tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tyrp1b-cH/Tyrp1b
Genetic Background: involves: 101/H * C3H/HeH * T Stock

Allelic Composition: Pscatm1Witt/Psca+,Tg(TRAMP)8247Ng/0
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0010357 increased prostate gland tumor incidence "greater than the expected number of neoplams in the prostate gland occurring in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tyrp1b-cH/Tyrp1b
Genetic Background: involves: 101/H * C3H/HeH * T Stock

Allelic Composition: Pscatm1Witt/Psca+,Tg(TRAMP)8247Ng/0
Genetic Background: involves: 129/Sv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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