ENSMUSG00000022681


Mus musculus

Features
Gene ID: ENSMUSG00000022681
  
Biological name :Ntan1
  
Synonyms : Mus musculus N-terminal Asn amidase (Ntan1), transcript variant 3, mRNA. / Ntan1 / Q64311
  
Possible biological names infered from orthology : N-terminal asparagine amidase / Q96AB6
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: A1
Gene start: 13818845
Gene end: 13835451
  
Corresponding Affymetrix probe sets: 10433691 (MoGene1.0st)   1423538_at (Mouse Genome 430 2.0 Array)   1447917_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000023362
Ensembl peptide - ENSMUSP00000111472
NCBI entrez gene - 18203     See in Manteia.
MGI - MGI:108471
RefSeq - XM_017316891
RefSeq - NM_001346106
RefSeq - NM_001346107
RefSeq - NM_010946
RefSeq - XM_006521851
RefSeq - XM_006521852
RefSeq - XM_006521853
RefSeq - XM_006521854
RefSeq - XM_006521855
RefSeq - XM_006521849
RefSeq - XM_006521850
RefSeq Peptide - NP_001333035
RefSeq Peptide - NP_001333036
RefSeq Peptide - NP_035076
swissprot - Q64311
swissprot - D3YZ99
Ensembl - ENSMUSG00000022681
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ntan1ENSDARG00000105182Danio rerio
 NTAN1ENSGALG00000040905Gallus gallus
 NTAN1ENSG00000157045Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026750  Protein N-terminal asparagine amidohydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0007613 memory IMP
 biological_processGO:0008344 adult locomotory behavior IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0008418 protein-N-terminal asparagine amidohydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Ntan1tm1Avar/Ntan1tm1Avar,Ubr1tm1Avar/Ubr1tm1Avar
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0001363 increased anxiety-related response "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060]
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Allelic Composition: Ntan1tm1Avar/Ntan1tm1Avar,Ubr1tm1Avar/Ubr1tm1Avar
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0001413 abnormal response to new environment "altered investigative behavior from controls in reactions associated with placing an animal in a new location" [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Ntan1tm1Avar/Ntan1tm1Avar,Ubr1tm1Avar/Ubr1tm1Avar
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0001463 abnormal spatial learning "defects in the abilibity to navigate using behavioraly meaningful locations" [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Ntan1tm1Avar/Ntan1tm1Avar,Ubr1tm1Avar/Ubr1tm1Avar
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ntan1tm1Avar/Ntan1tm1Avar,Ubr1tm1Avar/Ubr1tm1Avar
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0002444 abnormal T cell physiology "anomalous response of T lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Ntan1tm1Avar/Ntan1tm1Avar,Ubr1tm1Avar/Ubr1tm1Avar
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0002557 abnormal social/conspecific interaction "deviation of the normal behavior of mice towards each other" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Ntan1tm1Avar/Ntan1tm1Avar,Ubr1tm1Avar/Ubr1tm1Avar
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0002798 abnormal active avoidance behavior "defects in the ability to escape a hostile environment to actively avoid the unpleasant or punishing stimuli ( e.g. shock) previously encountered in this environment" [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Ntan1tm1Avar/Ntan1tm1Avar,Ubr1tm1Avar/Ubr1tm1Avar
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0005088 increased acute inflammation "greater than the expected early reaction of the microcirculation, characterized by movement of fluid and leukocytes from the blood into extravascular tissues; initiated by injury, infection, or local immune response " [Pathology:ISBN 0-397-51047-0]
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Allelic Composition: Ntan1tm1Avar/Ntan1tm1Avar,Ubr1tm1Avar/Ubr1tm1Avar
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0005156 bradykinesia "decreased spontaneity and movement" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83301]
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Allelic Composition: Ntan1tm1Avar/Ntan1tm1Avar,Ubr1tm1Avar/Ubr1tm1Avar
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0008432 abnormal long-term spatial reference memory "anomaly in long-term memory for spatial location information that is consolidated over hours and days after training or an encounter at that location" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ntan1tm1Avar/Ntan1tm1Avar,Ubr1tm1Avar/Ubr1tm1Avar
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0008770 decreased survivor rate "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Ntan1tm1Avar/Ntan1tm1Avar,Ubr1tm1Avar/Ubr1tm1Avar
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0009335 decreased splenocyte proliferation "reduction in the expansion rate of a splenocyte cell population by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ntan1tm1Avar/Ntan1tm1Avar,Ubr1tm1Avar/Ubr1tm1Avar
Genetic Background: involves: 129/Sv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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