ENSMUSG00000022765


Mus musculus

Features
Gene ID: ENSMUSG00000022765
  
Biological name :Snap29
  
Synonyms : Q9ERB0 / Snap29 / Synaptosomal-associated protein 29
  
Possible biological names infered from orthology : O95721 / synaptosome associated protein 29
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: A3
Gene start: 17406000
Gene end: 17430810
  
Corresponding Affymetrix probe sets: 10433996 (MoGene1.0st)   1423354_at (Mouse Genome 430 2.0 Array)   1423355_at (Mouse Genome 430 2.0 Array)   1423356_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000023449
NCBI entrez gene - 67474     See in Manteia.
MGI - MGI:1914724
RefSeq - NM_023348
RefSeq Peptide - NP_075837
swissprot - Q9ERB0
Ensembl - ENSMUSG00000022765
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 snap29ENSDARG00000038518Danio rerio
 SNAP29ENSGALG00000040128Gallus gallus
 O95721ENSG00000099940Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000727  Target SNARE coiled-coil homology domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016082 synaptic vesicle priming IBA
 biological_processGO:0016240 autophagosome membrane docking IEA
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0031629 synaptic vesicle fusion to presynaptic active zone membrane IBA
 biological_processGO:0060271 cilium assembly IEA
 biological_processGO:0097352 autophagosome maturation IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0000421 autophagosome membrane IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005776 autophagosome IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0020018 ciliary pocket membrane IEA
 cellular_componentGO:0031201 SNARE complex IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0060170 ciliary membrane IEA
 cellular_componentGO:0098793 presynapse IEA
 molecular_functionGO:0005484 SNAP receptor activity IBA
 molecular_functionGO:0019905 syntaxin binding IBA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Intra-Golgi traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000062 increased bone density "increased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295]
Show

Allelic Composition: Smstm1a(EUCOMM)Wtsi/Y
Genetic Background: B6JTyr;B6N-Smstm1a(EUCOMM)Wtsi/Wtsi

 MP:0000379 reduced hair follicle number "fewer number of the epidermal invaginations from which the hair shaft develops" [J:15108]
Show

Allelic Composition: Podxltm1Kmn/Podxl+
Genetic Background: either: (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlsHsd * C57BL/6)

 MP:0001192 scaly skin "skin covered with shedding scales or flakes" [J:65146]
Show

Allelic Composition: Podxltm1Kmn/Podxl+
Genetic Background: either: (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlsHsd * C57BL/6)

Allelic Composition: Snap29tm1c(EUCOMM)Wtsi/Snap29tm1c(EUCOMM)Wtsi,Tg(KRT14-cre)1Cgn/0
Genetic Background: involves: C57BL/6 * C57BL/6N * DBA/2

 MP:0001198 tight skin "skin has a taut, stretched appearance" [J:65038]
Show

Allelic Composition: Podxltm1Kmn/Podxl+
Genetic Background: either: (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlsHsd * C57BL/6)

Allelic Composition: Snap29tm1c(EUCOMM)Wtsi/Snap29tm1c(EUCOMM)Wtsi,Tg(KRT14-cre)1Cgn/0
Genetic Background: involves: C57BL/6 * C57BL/6N * DBA/2

 MP:0001216 abnormal epidermal layer morphology "anomalous structure or development of the superficial epithelial portion of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Podxltm1Kmn/Podxl+
Genetic Background: either: (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlsHsd * C57BL/6)

 MP:0001239 abnormal granular layer morphology "structural or developmental anomaly of the layer of flattened cells containing basophilic granules of keratohyalin and lying just above the stratum spinosum (spiny layer) of the epidermis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Podxltm1Kmn/Podxl+
Genetic Background: either: (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlsHsd * C57BL/6)

 MP:0001240 abnormal cornified layer morphology "structural or developmental anomaly of the outer layer of the epidermis, consisting of several layers of flat keratinized non-nucleated cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Podxltm1Kmn/Podxl+
Genetic Background: either: (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlsHsd * C57BL/6)

 MP:0001242 hyperkeratosis "increased depth of the corneal layer of the epidermis; thickening of the horny layer of the epidermis" [J:1133]
Show

Allelic Composition: Podxltm1Kmn/Podxl+
Genetic Background: either: (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlsHsd * C57BL/6)

Allelic Composition: Snap29tm1c(EUCOMM)Wtsi/Snap29tm1c(EUCOMM)Wtsi,Tg(KRT14-cre)1Cgn/0
Genetic Background: involves: C57BL/6 * C57BL/6N * DBA/2

 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
Show

Allelic Composition: Smstm1a(EUCOMM)Wtsi/Y
Genetic Background: B6JTyr;B6N-Smstm1a(EUCOMM)Wtsi/Wtsi

 MP:0001874 acanthosis "diffuse hyperplasia of the spinous layer of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Podxltm1Kmn/Podxl+
Genetic Background: either: (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlsHsd * C57BL/6)

Allelic Composition: Snap29tm1c(EUCOMM)Wtsi/Snap29tm1c(EUCOMM)Wtsi,Tg(KRT14-cre)1Cgn/0
Genetic Background: involves: C57BL/6 * C57BL/6N * DBA/2

 MP:0002656 abnormal keratinocyte differentiation "developmental anomaly of the cells of the epidermis that produce keratin in the process of differentiating into the dead and fully keratinized cells of the stratum corneum " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Snap29tm1c(EUCOMM)Wtsi/Snap29tm1c(EUCOMM)Wtsi,Tg(KRT14-cre)1Cgn/0
Genetic Background: involves: C57BL/6 * C57BL/6N * DBA/2

 MP:0002796 impaired skin barrier function "impaired ability of the skin to regulate water loss; frequently leads to dehydration" [J:56641]
Show

Allelic Composition: Snap29tm1c(EUCOMM)Wtsi/Snap29tm1c(EUCOMM)Wtsi,Tg(KRT14-cre)1Cgn/0
Genetic Background: involves: C57BL/6 * C57BL/6N * DBA/2

 MP:0003960 increased lean body mass "more than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
Show

Allelic Composition: Smstm1a(EUCOMM)Wtsi/Y
Genetic Background: B6JTyr;B6N-Smstm1a(EUCOMM)Wtsi/Wtsi

 MP:0005501 abnormal skin physiology "atypical function of the membranous protective covering of the body" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Podxltm1Kmn/Podxl+
Genetic Background: either: (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlsHsd * C57BL/6)

Allelic Composition: Snap29tm1c(EUCOMM)Wtsi/Snap29tm1c(EUCOMM)Wtsi,Tg(KRT14-cre)1Cgn/0
Genetic Background: involves: C57BL/6 * C57BL/6N * DBA/2

 MP:0008260 abnormal autophagy "abnormal catabolic process involving the degradation of a cell s own components through the lysosomal machinery" [MGI:honda "Hiraoki Onda, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Podxltm1Kmn/Podxl+
Genetic Background: either: (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlsHsd * C57BL/6)

 MP:0009546 absent gastric milk in neonates "failure of nursing offspring to ingest milk as indicated by stomach content" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Snap29tm1c(EUCOMM)Wtsi/Snap29tm1c(EUCOMM)Wtsi,Tg(KRT14-cre)1Cgn/0
Genetic Background: involves: C57BL/6 * C57BL/6N * DBA/2

 MP:0009583 increased keratinocyte proliferation "increase in the expansion rate of keratinocytes by cell division" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Snap29tm1c(EUCOMM)Wtsi/Snap29tm1c(EUCOMM)Wtsi,Tg(KRT14-cre)1Cgn/0
Genetic Background: involves: C57BL/6 * C57BL/6N * DBA/2

 MP:0009605 decreased keratohyalin granule number "reduced number of the irregularly shaped basophilic granules in the cells of the stratum granulosum of the epidermis that may play a role in keratinization and barrier function" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Snap29tm1c(EUCOMM)Wtsi/Snap29tm1c(EUCOMM)Wtsi,Tg(KRT14-cre)1Cgn/0
Genetic Background: involves: C57BL/6 * C57BL/6N * DBA/2

 MP:0009608 abnormal lamellar body morphology "any structural anomaly of a membrane-bounded organelle, specialized for the storage and secretion various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae" [GO:0042599]
Show

Allelic Composition: Podxltm1Kmn/Podxl+
Genetic Background: either: (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlsHsd * C57BL/6)

Allelic Composition: Snap29tm1c(EUCOMM)Wtsi/Snap29tm1c(EUCOMM)Wtsi,Tg(KRT14-cre)1Cgn/0
Genetic Background: involves: C57BL/6 * C57BL/6N * DBA/2

 MP:0009703 decreased birth body size "reduction in average body size at birth compared to controls" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Podxltm1Kmn/Podxl+
Genetic Background: either: (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlsHsd * C57BL/6)

Allelic Composition: Snap29tm1c(EUCOMM)Wtsi/Snap29tm1c(EUCOMM)Wtsi,Tg(KRT14-cre)1Cgn/0
Genetic Background: involves: C57BL/6 * C57BL/6N * DBA/2

 MP:0009931 abnormal skin appearance "skin that looks different from the usual state" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Podxltm1Kmn/Podxl+
Genetic Background: either: (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlsHsd * C57BL/6)

Allelic Composition: Snap29tm1c(EUCOMM)Wtsi/Snap29tm1c(EUCOMM)Wtsi,Tg(KRT14-cre)1Cgn/0
Genetic Background: involves: C57BL/6 * C57BL/6N * DBA/2

 MP:0010123 increased bone mineral content "elevation in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Smstm1a(EUCOMM)Wtsi/Y
Genetic Background: B6JTyr;B6N-Smstm1a(EUCOMM)Wtsi/Wtsi

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Snap29tm1c(EUCOMM)Wtsi/Snap29tm1c(EUCOMM)Wtsi,Tg(KRT14-cre)1Cgn/0
Genetic Background: involves: C57BL/6 * C57BL/6N * DBA/2

 MP:0020352 abnormal endoplasmic reticulum physiology "any functional anomaly of the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells" [GO:0005783, ORCID: orcid.org/0000-0003-4606-0597]
Show

Allelic Composition: Podxltm1Kmn/Podxl+
Genetic Background: either: (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlsHsd * C57BL/6)

 MP:0020354 increased endoplasmic reticulum stress "increase in in the accumulation of misfolded or unfolded proteins in the endoplasmic reticulum lumen; this accumulation may be stimulated by genetic or enviromental factors" [ORCID: orcid.org/0000-0003-4606-0597]
Show

Allelic Composition: Podxltm1Kmn/Podxl+
Genetic Background: either: (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlsHsd * C57BL/6)

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
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