| MP:0000272 | abnormal aorta morphology | "structural anomaly of the main trunk of the systemic arteries" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0000364 | abnormal vascular regression | "premature regression or persistence of vessels programmed to regress and/or loss of vessels not programmed to regress" [smb:Susan M. Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0000678 | abnormal parathyroid gland morphology | "anomalous structure of one of the two small, paired endocrine glands, usually found embedded in the connective tissue capsule on the posterior surface of the thyroid gland; they secrete parathyroid hormone (PTH) that regulates calcium and phosphorous metabolism" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0000704 | abnormal thymus development | "anomaly in the formation and/or differentiation of the thymus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0000706 | small thymus | "reduced size of the thymus" [J:36561, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:31167] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0001575 | cyanosis | "a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60159] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0002127 | abnormal cardiovascular system morphology | "abnormal development of the heart or vascular tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ripply3tm1Sjt/Ripply3tm1Sjt,Tbx1tm1Bem/Tbx1tm1Bem
Genetic Background: involves: 129/Sv * 129S1/Sv * C57BL/6J * SJL
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| MP:0002191 | abnormal artery morphology | "malformation of the blood vessels that carry blood away from the heart" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0002950 | abnormal neural crest cell migration | "defect in the dispersion of the transient and migratory group of cells that emerge from the dorsal region of the neural tube and migrate to many peripheral locations to form various tissues of the adult" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0003007 | ectopic thymus | "ectopic location of the thymus primordium, which normally resides in the superior mediastinum and lower part of the neck" [ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator, J:76015] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0003395 | abnormal subclavian artery morphology | "malformation of the right or left subclavian arteries, The right subclavian artery extends from the brachiocephalic artery to the right side of the body. The left subclavian artery extends from the aortic arch to the left side of the body." [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0003955 | abnormal ultimobranchial body | "a sac-like structure emanating from the caudal-most branchial pouch of the embryo; develops into the lateral portion of the thyroid that produced calcitonin in higher vertebrates" [hdene:Howard Dene , Mouse Genome Informatics Curator] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0004157 | interrupted aortic arch | "complete discontinuation/blockage between the ascending and descending aorta; includes Type A, interruption distal to the subclavian artery that is ipsilateral to the second carotid artery, and Type B, interruption between second carotid artery and ipsilateral subclavian artery" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0005561 | increased mean corpuscular hemoglobin | "greater than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Otud7btm1(NCOM)Cmhd/Otud7btm1(NCOM)Cmhd
Genetic Background: C57BL/6N-Otud7btm1(NCOM)Cmhd/Tcp
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| MP:0006031 | abnormal branchial pouch morphology | "malfomation or anomaly in the series of grooves that form between the branchial arches; these endodermal evaginations develop into epithelial tissues and organs" [smb:Susan M Bello, Mouse Genome Informatics Curator, Gray s Anatomy:ISBN 0-914294-08-3] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
Allelic Composition: Ripply3tm1Sjt/Ripply3tm1Sjt,Tbx1tm1Bem/Tbx1tm1Bem
Genetic Background: involves: 129/Sv * 129S1/Sv * C57BL/6J * SJL
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| MP:0006339 | abnormal third branchial arch morphology | "anomaly in the structure of the third are which contributes to the development of the hyoid bone, stylopharyngeus muscle, inferior parathyroid gland, and thymus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0006340 | abnormal fourth branchial arch morphology | "anomaly in the structure of the fourth arch which contributes to development of the cartilage of the larynx, laryngeal, pharyngeal, and soft palate muscles, superior parathyroid gland, and C-cells of the thymus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", zillmusom:http://musom.marshall.edu/anatomy/grosshom/z_devbranc.html] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
Allelic Composition: Ripply3tm1Sjt/Ripply3+,Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129/Sv * 129S1/Sv * C57BL/6J * SJL
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| MP:0006346 | small branchial arch | "reduced size of one or more of the branchial arches" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
Allelic Composition: Ripply3tm1Sjt/Ripply3+,Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129/Sv * 129S1/Sv * C57BL/6J * SJL
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| MP:0009113 | increased pancreatic beta cell mass | "greater total physical bulk or volume of a pancreatic beta cell compared to the normal state" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0010356 | abnormal second branchial arch artery morphology | "any structural anomaly of the vessels formed within the second pair of branchial arches in embryogenesis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0010395 | abnormal branchial arch development | "abnormal formation of the of the transient structures of the embryo that develop into regions of the head, neck and ears" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0010402 | ventricular septal defect | "abnormal communications between the two lower chambers of the heart, including such defects in the perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular regions" [MESH:C14.240.400.560.540] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0010564 | abnormal fetal ductus arteriosus morphology | "any structural anomaly of the fetal vessel that connects the left pulmonary artery with the descending aorta; the ductus arteriosus normally regresses into a fibrous cord, the ligamentum arteriousum after birth" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0011819 | increased pancreatic beta cell proliferation | "increase in the ability of the cells that secrete insulin and are located towards the center of the islets of Langerhans in the pancreas to undergo expansion by cell division" [CL:0000169] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0030335 | absent third pharyngeal arch artery | "failure to develop or absence of the third pharyngeal arch artery" [MGI:anna] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0030340 | absent fourth pharyngeal arch artery | "failure to develop or absence of the fourth pharyngeal arch artery" [MGI:anna] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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| MP:0030589 | increased pancreatic alpha cell mass | "greater total physical bulk or volume of a pancreatic alpha cell compared to the normal state" [MGI:anna] |
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Allelic Composition: Cochtm1.1Stw/Coch+
Genetic Background: CBA/Ca.129S1-Cochtm1.1Stw
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