ENSMUSG00000023057


Mus musculus

Features
Gene ID: ENSMUSG00000023057
  
Biological name :Fabp2
  
Synonyms : Fabp2 / Fatty acid-binding protein, intestinal / P55050
  
Possible biological names infered from orthology : fatty acid binding protein 2 / P12104
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: G1
Gene start: 122895072
Gene end: 122899506
  
Corresponding Affymetrix probe sets: 10495820 (MoGene1.0st)   1418438_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000023820
NCBI entrez gene - 14079     See in Manteia.
MGI - MGI:95478
RefSeq - NM_007980
RefSeq Peptide - NP_032006
swissprot - P55050
swissprot - Q53YP5
Ensembl - ENSMUSG00000023057
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fabp2ENSDARG00000006427Danio rerio
 FABP2ENSGALG00000011986Gallus gallus
 FABP2ENSG00000145384Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000463  Cytosolic fatty-acid binding
 IPR000566  Lipocalin/cytosolic fatty-acid binding domain
 IPR012674  Calycin
 IPR031259  Intracellular lipid binding protein
 IPR031272  Fatty acid-binding protein, intestinal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0098856 intestinal lipid absorption IEA
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005504 fatty acid binding IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0036041 long-chain fatty acid binding IEA


Pathways (from Reactome)
Pathway description
Triglyceride catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002079 increased circulating insulin level "greater than normal levels of insulin in blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Ift88Tg737Rpw/Ift88Tg737Rpw
Genetic Background: involves: FVB/N

 MP:0002981 increased liver weight "a greater than average weight of the bile-secreting exocrine gland" [il:Ira Lu , Mouse Genome Informatics Curator]
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Allelic Composition: Ift88Tg737Rpw/Ift88Tg737Rpw
Genetic Background: involves: FVB/N

 MP:0003402 decreased liver weight "reduced average weight of the bile-secreting exocrine gland" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ift88Tg737Rpw/Ift88Tg737Rpw
Genetic Background: involves: FVB/N

 MP:0003443 increased circulating glycerol level "higher than normal concentration of glycerol in the blood" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Ift88Tg737Rpw/Ift88Tg737Rpw
Genetic Background: involves: FVB/N

 MP:0003917 increased kidney weight "greater heft of the organs responsible for urine secretion" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Ift88Tg737Rpw/Ift88Tg737Rpw
Genetic Background: involves: FVB/N

 MP:0003949 abnormal circulating lipid level "anomalous concentrations of fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water) in the blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Ift88Tg737Rpw/Ift88Tg737Rpw
Genetic Background: involves: FVB/N

 MP:0005179 decreased total circulating cholesterol level "less than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ift88Tg737Rpw/Ift88Tg737Rpw
Genetic Background: involves: FVB/N

 MP:0005658 susceptibility to diet-induced obesity "more likely to become excessively fat or to increase fat in the subcutaneous connective tissue as a result of consuming a diet geared to increase body fat " [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator]
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Allelic Composition: Ift88Tg737Rpw/Ift88Tg737Rpw
Genetic Background: involves: FVB/N

 MP:0005659 resistance to diet-induced obesity "less likely to become excessively fat or to increase fat in the subcutaneous connective tissue as a result of consuming a diet geared to increase body fat " [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator]
Show

Allelic Composition: Ift88Tg737Rpw/Ift88Tg737Rpw
Genetic Background: involves: FVB/N

 MP:0005669 increased circulating leptin level "greater than the normal blood concentration of the peptide hormone secreted by white adipocytes and believed to regulate food intake and energy balance" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, J:34751]
Show

Allelic Composition: Ift88Tg737Rpw/Ift88Tg737Rpw
Genetic Background: involves: FVB/N

 MP:0009288 increased epididymal fat pad weight 
Show

Allelic Composition: Ift88Tg737Rpw/Ift88Tg737Rpw
Genetic Background: involves: FVB/N

 MP:0009307 decreased uterine fat pad weight 
Show

Allelic Composition: Ift88Tg737Rpw/Ift88Tg737Rpw
Genetic Background: involves: FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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